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PDB: 901 results

4N62
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Crystal structure of hemagglutinin from an H7N9 influenza virus in complex with a sulfated receptor analog
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin HA1, Hemagglutinin HA2, ...
Authors:Xu, R, Wilson, I.A.
Deposit date:2013-10-11
Release date:2013-12-18
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.5026 Å)
Cite:Preferential recognition of avian-like receptors in human influenza A H7N9 viruses.
Science, 342, 2013
4N60
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BU of 4n60 by Molmil
Crystal structure of hemagglutinin from an H7N9 influenza virus in complex with LSTc
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin HA1, Hemagglutinin HA2, ...
Authors:Xu, R, Wilson, I.A.
Deposit date:2013-10-11
Release date:2013-12-18
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.9032 Å)
Cite:Preferential recognition of avian-like receptors in human influenza A H7N9 viruses.
Science, 342, 2013
4MAS
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BU of 4mas by Molmil
High Resolution Structure of Wild Type Human Transthyretin in Complex with 3,3',5,5'-tetrachloro-[1,1'-biphenyl]-4,4'diol
Descriptor: 3,5,3',5'-TETRACHLORO-BIPHENYL-4,4'-DIOL, Transthyretin
Authors:Connelly, S, Bradbury, N.C, Wilson, I.A.
Deposit date:2013-08-16
Release date:2013-09-25
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.22 Å)
Cite:High Resolution Structure of Wild Type Human Transthyretin in Complex with 3,3',5,5'-tetrachloro-[1,1'-biphenyl]-4,4'diol
To be Published
4QDH
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BU of 4qdh by Molmil
Crystal Structure of the C-terminal Domain of Mouse TLR9
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, SULFATE ION, Variable lymphocyte receptor B, ...
Authors:Collins, B.C, Wilson, I.A.
Deposit date:2014-05-13
Release date:2014-06-11
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.399 Å)
Cite:Crystal structure of the C-terminal domain of mouse TLR9.
Proteins, 82, 2014
6AVN
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BU of 6avn by Molmil
Crystal structure of unbound anti-HIV antibody Fab PGV19 at 2.5 A
Descriptor: GLYCEROL, PENTAETHYLENE GLYCOL, PGV19 Fab heavy chain, ...
Authors:Sarkar, A, Wilson, I.A.
Deposit date:2017-09-03
Release date:2018-06-27
Last modified:2024-10-09
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structure of a cleavage-independent HIV Env recapitulates the glycoprotein architecture of the native cleaved trimer.
Nat Commun, 9, 2018
6AOP
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Crystal structure of the A/Brisbane/10/2007 (H3N2) influenza virus hemagglutinin L194P mutant apo form
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin HA1 chain, ...
Authors:Wu, N.C, Wilson, I.A.
Deposit date:2017-08-16
Release date:2017-10-18
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:A structural explanation for the low effectiveness of the seasonal influenza H3N2 vaccine.
PLoS Pathog., 13, 2017
6AOS
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BU of 6aos by Molmil
Crystal structure of the A/Brisbane/10/2007 (H3N2) influenza virus hemagglutinin L194P mutant in complex with 3'-SLNLN
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin HA1 chain, ...
Authors:Wu, N.C, Wilson, I.A.
Deposit date:2017-08-16
Release date:2017-10-18
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:A structural explanation for the low effectiveness of the seasonal influenza H3N2 vaccine.
PLoS Pathog., 13, 2017
6AOQ
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Crystal structure of the A/Brisbane/10/2007 (H3N2) influenza virus hemagglutinin apo form
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin HA2 chain, ...
Authors:Wu, N.C, Wilson, I.A.
Deposit date:2017-08-16
Release date:2017-10-18
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:A structural explanation for the low effectiveness of the seasonal influenza H3N2 vaccine.
PLoS Pathog., 13, 2017
6AOU
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BU of 6aou by Molmil
Crystal structure of the A/Brisbane/10/2007 (H3N2) influenza virus hemagglutinin in complex with 3'-SLNLN
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin HA1 chain, ...
Authors:Wu, N.C, Wilson, I.A.
Deposit date:2017-08-16
Release date:2017-10-18
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:A structural explanation for the low effectiveness of the seasonal influenza H3N2 vaccine.
PLoS Pathog., 13, 2017
6AOV
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BU of 6aov by Molmil
Crystal structure of the A/Brisbane/10/2007 (H3N2) influenza virus hemagglutinin in complex with 6'-SLNLN
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin HA1 chain, ...
Authors:Wu, N.C, Wilson, I.A.
Deposit date:2017-08-16
Release date:2017-10-18
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:A structural explanation for the low effectiveness of the seasonal influenza H3N2 vaccine.
PLoS Pathog., 13, 2017
6B3D
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BU of 6b3d by Molmil
Crystal structure of anti-HIV antibody PGT128 in complex with a bacterially derived synthetic mimetic of Man9.
Descriptor: 1,2-ETHANEDIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, GLYCEROL, ...
Authors:Murrell, S, Wilson, I.A.
Deposit date:2017-09-21
Release date:2017-12-06
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.271 Å)
Cite:Bacterially derived synthetic mimetics of mammalian oligomannose prime antibody responses that neutralize HIV infectivity.
Nat Commun, 8, 2017
6AOR
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Crystal structure of the A/Brisbane/10/2007 (H3N2) influenza virus hemagglutinin apo form
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin HA2 chain, ...
Authors:Wu, N.C, Wilson, I.A.
Deposit date:2017-08-16
Release date:2017-10-18
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:A structural explanation for the low effectiveness of the seasonal influenza H3N2 vaccine.
PLoS Pathog., 13, 2017
6AXL
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BU of 6axl by Molmil
Crystal structure of Fab317 complex
Descriptor: Fab317 heavy chain, Fab317 light chains, Peptide ACE-ASN-PRO-ASN-ALA-ASN-PRO-ASN-ALA-ASN-PRO-ASN-ALA-NH2
Authors:Oyen, D, Wilson, I.A.
Deposit date:2017-09-07
Release date:2017-11-22
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural basis for antibody recognition of the NANP repeats in Plasmodium falciparum circumsporozoite protein.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
6AXK
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BU of 6axk by Molmil
Crystal structure of Fab311 complex
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ACE-ASN-PRO-ASN-ALA-ASN-PRO-ASN-ALA-ASN-PRO-ASN, Fab311 heavy chain, ...
Authors:Oyen, D, Wilson, I.A.
Deposit date:2017-09-07
Release date:2017-11-22
Last modified:2024-10-09
Method:X-RAY DIFFRACTION (2.103 Å)
Cite:Structural basis for antibody recognition of the NANP repeats in Plasmodium falciparum circumsporozoite protein.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
6AOT
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BU of 6aot by Molmil
Crystal structure of the A/Brisbane/10/2007 (H3N2) influenza virus hemagglutinin L194P mutant in complex with 6'-SLNLN
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin HA1 chain, ...
Authors:Wu, N.C, Wilson, I.A.
Deposit date:2017-08-16
Release date:2017-10-18
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:A structural explanation for the low effectiveness of the seasonal influenza H3N2 vaccine.
PLoS Pathog., 13, 2017
6BKB
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BU of 6bkb by Molmil
Structure of Hepatitis C Virus Envelope Glycoprotein E2 core from genotype 6a bound to broadly neutralizing antibody AR3A
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Fab AR3A heavy chain, ...
Authors:Tzarum, N, Wilson, I.A, Law, M.
Deposit date:2017-11-08
Release date:2018-12-26
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.799 Å)
Cite:Genetic and structural insights into broad neutralization of hepatitis C virus by human VH1-69 antibodies.
Sci Adv, 5, 2019
6BZV
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BU of 6bzv by Molmil
Structure of the Hepatitis C virus envelope glycoprotein E2 antigenic region 412-423 bound to the GL precursor of the broadly neutralizing antibody 19B3
Descriptor: 19B3 GL Heavy Chain, 19B3 GL Light Chain, E2 AS412 peptide
Authors:Tzarum, N, Aleman, F, Wilson, I.A, Law, M.
Deposit date:2017-12-26
Release date:2018-06-20
Last modified:2022-02-02
Method:X-RAY DIFFRACTION (2.654 Å)
Cite:Immunogenetic and structural analysis of a class of HCV broadly neutralizing antibodies and their precursors.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6BKP
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BU of 6bkp by Molmil
Crystal structure of the A/Michigan/15/2014 (H3N2) influenza virus hemagglutinin apo form
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin, ...
Authors:Wu, N.C, Wilson, I.A.
Deposit date:2017-11-09
Release date:2018-02-28
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:A complex epistatic network limits the mutational reversibility in the influenza hemagglutinin receptor-binding site.
Nat Commun, 9, 2018
6BKD
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BU of 6bkd by Molmil
Structure of Hepatitis C Virus Envelope Glycoprotein E2 core from genotype 6a bound to broadly neutralizing antibody AR3D
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Fab AR3D heavy chain, Fab AR3D light chain, ...
Authors:Tzarum, N, Wilson, I.A, Law, M.
Deposit date:2017-11-08
Release date:2018-12-26
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (3.25 Å)
Cite:Genetic and structural insights into broad neutralization of hepatitis C virus by human VH1-69 antibodies.
Sci Adv, 5, 2019
6BKN
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BU of 6bkn by Molmil
Crystal structure of the A/Wyoming/3/2003 (H3N2) influenza virus hemagglutinin apo form
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin, ...
Authors:Wu, N.C, Wilson, I.A.
Deposit date:2017-11-09
Release date:2018-02-28
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:A complex epistatic network limits the mutational reversibility in the influenza hemagglutinin receptor-binding site.
Nat Commun, 9, 2018
6CE0
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BU of 6ce0 by Molmil
Crystal structure of a HIV-1 clade B tier-3 isolate H078.14 UFO-BG Env trimer in complex with broadly neutralizing Fabs PGT124 and 35O22 at 4.6 Angstrom
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 35O22 Heavy chain, ...
Authors:Kumar, S, Sarkar, A, Wilson, I.A.
Deposit date:2018-02-09
Release date:2018-12-05
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (4.602 Å)
Cite:HIV-1 vaccine design through minimizing envelope metastability.
Sci Adv, 4, 2018
6CJK
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BU of 6cjk by Molmil
Anti HIV Fab 10A
Descriptor: ACETATE ION, GLYCEROL, Immunoglobulin Fab heavy chain, ...
Authors:Hangartner, L, Ward, A.B, Wilson, I.A, Oyen, D.
Deposit date:2018-02-26
Release date:2018-08-15
Last modified:2019-12-18
Method:X-RAY DIFFRACTION (1.795 Å)
Cite:Electron-Microscopy-Based Epitope Mapping Defines Specificities of Polyclonal Antibodies Elicited during HIV-1 BG505 Envelope Trimer Immunization.
Immunity, 49, 2018
6CA9
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BU of 6ca9 by Molmil
Crystal structure of Fab PCT64_LMCA (SAR), the least mutated common ancestor of the HIV-1 broadly neutralizing antibody lineage PCT64
Descriptor: DI(HYDROXYETHYL)ETHER, GLYCEROL, PCT64_LMCA Fab heavy chain, ...
Authors:Omorodion, O, Wilson, I.A.
Deposit date:2018-01-29
Release date:2018-06-27
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.702 Å)
Cite:Co-evolution of HIV Envelope and Apex-Targeting Neutralizing Antibody Lineage Provides Benchmarks for Vaccine Design.
Cell Rep, 23, 2018
6CA7
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BU of 6ca7 by Molmil
Crystal structure of PCT64_13C, a strain specific anti-HIV antibody
Descriptor: PCT64_13C heavy chain, PCT64_13C light chain
Authors:Murrell, S, Wilson, I.A.
Deposit date:2018-01-29
Release date:2018-06-27
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.643 Å)
Cite:Co-evolution of HIV Envelope and Apex-Targeting Neutralizing Antibody Lineage Provides Benchmarks for Vaccine Design.
Cell Rep, 23, 2018
6CFG
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BU of 6cfg by Molmil
Crystal structure of the A/Vietnam/1203/2004 (H5N1) influenza virus hemagglutinin in complex with small molecule JNJ4796
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, DI(HYDROXYETHYL)ETHER, ...
Authors:Kadam, R.U, Wilson, I.A.
Deposit date:2018-02-14
Release date:2019-02-13
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.32 Å)
Cite:A small-molecule fusion inhibitor of influenza virus is orally active in mice.
Science, 363, 2019

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