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PDB: 871 results

2QGD
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Human transthyretin (TTR) complexed with 2-(3,5-Dibromo-4-hydroxyphenyl)benzoxazole
Descriptor: 4-(1,3-BENZOXAZOL-2-YL)-2,6-DIBROMOPHENOL, Transthyretin
Authors:Connelly, S, Wilson, I.A.
Deposit date:2007-06-28
Release date:2008-02-05
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Biochemical and structural evaluation of highly selective 2-arylbenzoxazole-based transthyretin amyloidogenesis inhibitors.
J.Med.Chem., 51, 2008
2QGC
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Human transthyretin (TTR) complexed with 2-(3,5-Dimethyl-4-hydroxyphenyl)benzoxazole
Descriptor: 4-(1,3-BENZOXAZOL-2-YL)-2,6-DIMETHYLPHENOL, Transthyretin
Authors:Connelly, S, Wilson, I.A.
Deposit date:2007-06-28
Release date:2008-02-05
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Biochemical and structural evaluation of highly selective 2-arylbenzoxazole-based transthyretin amyloidogenesis inhibitors.
J.Med.Chem., 51, 2008
2QSC
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BU of 2qsc by Molmil
Crystal structure analysis of anti-HIV-1 V3-Fab F425-B4e8 in complex with a V3-peptide
Descriptor: CHLORIDE ION, Envelope glycoprotein gp120, Fab F425-B4e8, ...
Authors:Bell, C.H, Schiefner, A, Stanfield, R.L, Wilson, I.A.
Deposit date:2007-07-30
Release date:2008-01-15
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structure of antibody F425-B4e8 in complex with a V3 peptide reveals a new binding mode for HIV-1 neutralization.
J.Mol.Biol., 375, 2008
2R6Q
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Crystal Structure of BclA-island Construct
Descriptor: BclA protein
Authors:Han, B.W, Herrin, B.R, Turnbough Jr, C.L, Cooper, M.D, Wilson, I.A.
Deposit date:2007-09-06
Release date:2009-03-10
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.43 Å)
Cite:Crystal structure of BclA-island Construct
To be Published
2R9U
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BU of 2r9u by Molmil
Crystal Structure of Lamprey Variable Lymphocyte Receptor 2913 Ectodomain
Descriptor: Variable lymphocyte receptor
Authors:Han, B.W, Herrin, B.R, Choe, J, Cooper, M.D, Wilson, I.A.
Deposit date:2007-09-13
Release date:2009-03-10
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal Structure of Lamprey Variable Lymphocyte Receptor 2913 Ectodomain.
To be Published
8F0I
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Crystal structure of SARS-CoV-2 receptor binding domain in complex with human antibody COVA309-22
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, COVA309-22 heavy chain, COVA309-22 light chain, ...
Authors:Yuan, M, Wilson, I.A.
Deposit date:2022-11-03
Release date:2023-09-13
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (3.7 Å)
Cite:Broad SARS-CoV-2 neutralization by monoclonal and bispecific antibodies derived from a Gamma-infected individual.
Iscience, 26, 2023
2YMN
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BU of 2ymn by Molmil
Organization of the Influenza Virus Replication Machinery
Descriptor: NUCLEOPROTEIN
Authors:Moeller, A, Kirchdoerfer, R.N, Potter, C.S, Carragher, B, Wilson, I.A.
Deposit date:2012-10-09
Release date:2012-12-05
Last modified:2024-05-08
Method:ELECTRON MICROSCOPY (20 Å)
Cite:Organization of the Influenza Virus Replication Machinery.
Science, 338, 2012
5AWN
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BU of 5awn by Molmil
Crystal structure of Human anti-HIV-1 broadly neutralizing antibody 3BC176 Fab
Descriptor: Heavy chain of 3BC176 Fab, Light chain of 3BC176 Fab
Authors:Lee, J.H, Wilson, I.A, Ward, A.B.
Deposit date:2015-07-06
Release date:2015-11-11
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.887 Å)
Cite:Antibodies to a conformational epitope on gp41 neutralize HIV-1 by destabilizing the Env spike.
Nat Commun, 6, 2015
6KVA
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Structure of anti-hCXCR2 abN48-2 in complex with its CXCR2 epitope
Descriptor: 1,2-ETHANEDIOL, Peptide from C-X-C chemokine receptor type 2, heavy chain, ...
Authors:Xiang, J.C, Yan, L, Yang, B, Wilson, I.A.
Deposit date:2019-09-03
Release date:2020-09-09
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Selection of a picomolar antibody that targets CXCR2-mediated neutrophil activation and alleviates EAE symptoms.
Nat Commun, 12, 2021
6KZ0
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HRV14 3C in complex with single chain antibody GGVV
Descriptor: GGVV H chain, GGVV L chain, Genome polyprotein
Authors:Meng, B, Yang, B, Wilson, I.A.
Deposit date:2019-09-21
Release date:2020-05-27
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Inhibitory antibodies identify unique sites of therapeutic vulnerability in rhinovirus and other enteroviruses.
Proc.Natl.Acad.Sci.USA, 117, 2020
6KVF
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Structure of anti-hCXCR2 abN48 in complex with its CXCR2 epitope
Descriptor: Peptide from C-X-C chemokine receptor type 2, heavy chain, light chain
Authors:Xiang, J.C, Yan, L, Yang, B, Wilson, I.A.
Deposit date:2019-09-04
Release date:2020-09-09
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.79 Å)
Cite:Selection of a picomolar antibody that targets CXCR2-mediated neutrophil activation and alleviates EAE symptoms.
Nat Commun, 12, 2021
6KYZ
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HRV14 3C in complex with single chain antibody YDF
Descriptor: Genome polyprotein, YDF H chain, YDF L chain
Authors:Meng, B, Yang, B, Wilson, I.A.
Deposit date:2019-09-20
Release date:2020-05-27
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.845 Å)
Cite:Inhibitory antibodies identify unique sites of therapeutic vulnerability in rhinovirus and other enteroviruses.
Proc.Natl.Acad.Sci.USA, 117, 2020
6M87
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Fab 10A6 in complex with MPTS
Descriptor: 8-methoxypyrene-1,3,6-trisulfonic acid, Fab 10A6 heavy chain, Fab 10A6 light chain, ...
Authors:Stanfield, R.L, Wilson, I.A.
Deposit date:2018-08-21
Release date:2019-07-03
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.609 Å)
Cite:Structure and Dynamics of Stacking Interactions in an Antibody Binding Site.
Biochemistry, 58, 2019
5C7K
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Crystal structure BG505 SOSIP gp140 HIV-1 Env trimer bound to broadly neutralizing antibodies PGT128 and 8ANC195
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Antibody Fab 8ANC195 heavy chain, ...
Authors:Kong, L, Stanfield, R.L, Wilson, I.A.
Deposit date:2015-06-24
Release date:2015-10-07
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (4.6019 Å)
Cite:Complete epitopes for vaccine design derived from a crystal structure of the broadly neutralizing antibodies PGT128 and 8ANC195 in complex with an HIV-1 Env trimer.
Acta Crystallogr.,Sect.D, 71, 2015
5BZD
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Crystal Structure of PCDN-27A, an antibody from the PCDN family of HIV-1 antibodies
Descriptor: 5G8 HIV Antibody heavy chain, 5G8 HIV Antibody light chain, GLYCEROL
Authors:Garces, F, WILSON, I.A.
Deposit date:2015-06-11
Release date:2016-05-25
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Early Antibody Lineage Diversification and Independent Limb Maturation Lead to Broad HIV-1 Neutralization Targeting the Env High-Mannose Patch
Immunity, 44, 2016
5BZW
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BU of 5bzw by Molmil
Crystal Structure of PCDN-27B, an antibody from the PCDN family of HIV-1 antibodies
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2B3 HIV Antibody heavy chain, 2B3 HIV Antibody light chain, ...
Authors:Garces, F, WILSON, I.A.
Deposit date:2015-06-11
Release date:2016-05-25
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Early Antibody Lineage Diversification and Independent Limb Maturation Lead to Broad HIV-1 Neutralization Targeting the Env High-Mannose Patch.
Immunity, 44, 2016
6ME1
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BU of 6me1 by Molmil
Crystal structure of the clade B isolate B41 mutant fusion peptide (residues 512-521) in complex with VRC34.01
Descriptor: Envelope glycoprotein gp160, VRC34.01 Fab heavy chain, VRC34.01 Fab light chain
Authors:Kumar, S, Sarkar, A, Wilson, I.A.
Deposit date:2018-09-05
Release date:2019-02-27
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.97 Å)
Cite:Capturing the inherent structural dynamics of the HIV-1 envelope glycoprotein fusion peptide.
Nat Commun, 10, 2019
6MG4
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Structure of full-length human lambda-6A light chain JTO
Descriptor: JTO light chain
Authors:Morgan, G.J, Yan, N.L, Mortenson, D.E, Stanfield, R.L, Wilson, I.A, Kelly, J.W.
Deposit date:2018-09-12
Release date:2019-04-10
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Stabilization of amyloidogenic immunoglobulin light chains by small molecules.
Proc.Natl.Acad.Sci.USA, 116, 2019
5CCK
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Crystal structure of Human anti-HIV-1 broadly neutralizing antibody 3BC315 Fab
Descriptor: 3-CYCLOHEXYL-1-PROPYLSULFONIC ACID, Antibody 3BC315 Fab heavy chain, Antibody 3BC315 Fab light chain
Authors:Lee, J.H, Ward, A.B, Wilson, I.A.
Deposit date:2015-07-02
Release date:2015-10-07
Last modified:2019-12-11
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Antibodies to a conformational epitope on gp41 neutralize HIV-1 by destabilizing the Env spike.
Nat Commun, 6, 2015
5CJQ
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BU of 5cjq by Molmil
Crystal structure of a trimeric influenza hemagglutinin stem in complex with an broadly neutralizing antibody CR9114
Descriptor: CR9114 heavy chain, CR9114 light chain, Designed influenza hemagglutinin stem #4900, ...
Authors:Zhu, X, Wilson, I.A.
Deposit date:2015-07-14
Release date:2015-09-09
Last modified:2015-09-30
Method:X-RAY DIFFRACTION (3.6 Å)
Cite:A stable trimeric influenza hemagglutinin stem as a broadly protective immunogen.
Science, 349, 2015
6MCO
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Crystal structure of the B41 SOSIP.664 Env trimer with PGT124 and 35O22 Fabs, in P23 space group
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 35O22 Fab heavy chain, ...
Authors:Kumar, S, Sarkar, A, Wilson, I.A.
Deposit date:2018-08-31
Release date:2019-02-27
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (3.526 Å)
Cite:Capturing the inherent structural dynamics of the HIV-1 envelope glycoprotein fusion peptide.
Nat Commun, 10, 2019
6MG5
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Structure of full-length human lambda-6A light chain JTO in complex with coumarin 1
Descriptor: 7-(diethylamino)-4-methyl-2H-1-benzopyran-2-one, Light chain JTO, PHOSPHATE ION
Authors:Morgan, G.J, Yan, N.L, Mortenson, D.E, Stanfield, R.L, Wilson, I.A, Kelly, J.W.
Deposit date:2018-09-12
Release date:2019-04-10
Last modified:2019-12-25
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Stabilization of amyloidogenic immunoglobulin light chains by small molecules.
Proc.Natl.Acad.Sci.USA, 116, 2019
6MDT
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BU of 6mdt by Molmil
Crystal structure of the B41 SOSIP.664 Env trimer with PGT124 and 35O22 Fabs, in P63 space group
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 35O22 Fab heavy chain, ...
Authors:Kumar, S, Sarkar, A, Wilson, I.A.
Deposit date:2018-09-05
Release date:2019-02-27
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (3.816 Å)
Cite:Capturing the inherent structural dynamics of the HIV-1 envelope glycoprotein fusion peptide.
Nat Commun, 10, 2019
5CEX
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BU of 5cex by Molmil
Crystal Structure of Fab 32H+109L, a putative precursor of the PGT121 family of potent HIV-1 antibodies
Descriptor: Antibody 9H+3L Fab heavy chain, Antibody 9H+3L Fab light chain, GLYCEROL, ...
Authors:Garces, F, Wilson, I.A.
Deposit date:2015-07-07
Release date:2015-12-23
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.105 Å)
Cite:Affinity Maturation of a Potent Family of HIV Antibodies Is Primarily Focused on Accommodating or Avoiding Glycans.
Immunity, 43, 2015
5CJS
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Crystal structure of a monomeric influenza hemagglutinin stem in complex with an broadly neutralizing antibody CR9114
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CR9114 heavy chain, CR9114 light chain, ...
Authors:Zhu, X, Wilson, I.A.
Deposit date:2015-07-15
Release date:2015-09-09
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (4.3 Å)
Cite:A stable trimeric influenza hemagglutinin stem as a broadly protective immunogen.
Science, 349, 2015

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