7S0I

CRYSTAL STRUCTURE OF N1 NEURAMINIDASE FROM A/Michigan/45/2015(H1N1)

Summary for 7S0I

• Entry DOI: 10.2210/pdb7s0i/pdb
• Descriptor: Neuraminidase, alpha-D-mannopyranose-(1-3)-alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (5 entities in total)
• Functional Keywords: influenza a virus, h1n1, neuraminidase, head domain, measles virus phosphoprotein tetramerization domain, hydrolase
• Biological source: Influenza A virus (A/Michigan/45/2015(H1N1))
• Total number of polymer chains: 1
• Total formula weight: 44354.46

Authors

Zhu, X.,Wilson, I.A. (deposition date: 2021-08-30, release date: 2021-12-08, Last modification date: 2023-10-18)

• Primary citation: Strohmeier, S.,Amanat, F.,Zhu, X.,McMahon, M.,Deming, M.E.,Pasetti, M.F.,Neuzil, K.M.,Wilson, I.A.,Krammer, F.; A Novel Recombinant Influenza Virus Neuraminidase Vaccine Candidate Stabilized by a Measles Virus Phosphoprotein Tetramerization Domain Provides Robust Protection from Virus Challenge in the Mouse Model.; Mbio, 12:e0224121-e0224121, 2021; PubMed: 34809451; DOI: 10.1128/mBio.02241-21

Experimental method

X-RAY DIFFRACTION (2.892 Å)