8EQA
Crystal structure of human anti-N1 neuraminidase 2H08 Fab
Summary for 8EQA
Entry DOI | 10.2210/pdb8eqa/pdb |
Related | 8e6k |
Descriptor | 2H08 Fab light chain, 2H08 Fab heavy chain, ZINC ION, ... (4 entities in total) |
Functional Keywords | antibody, neuraminidase, h1n1, broad protection, pandemic, immune system |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 4 |
Total formula weight | 95142.85 |
Authors | Zhu, X.,Wilson, I.A. (deposition date: 2022-10-07, release date: 2023-08-09, Last modification date: 2023-08-23) |
Primary citation | Hansen, L.,McMahon, M.,Turner, H.L.,Zhu, X.,Turner, J.S.,Ozorowski, G.,Stadlbauer, D.,Vahokoski, J.,Schmitz, A.J.,Rizk, A.A.,Alsoussi, W.B.,Strohmeier, S.,Yu, W.,Choreno-Parra, J.A.,Jimenez-Alvarez, L.,Cruz-Lagunas, A.,Zuniga, J.,Mudd, P.A.,Cox, R.J.,Wilson, I.A.,Ward, A.B.,Ellebedy, A.H.,Krammer, F. Human anti-N1 monoclonal antibodies elicited by pandemic H1N1 virus infection broadly inhibit HxN1 viruses in vitro and in vivo. Immunity, 56:1927-, 2023 Cited by PubMed: 37506693DOI: 10.1016/j.immuni.2023.07.004 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.55 Å) |
Structure validation
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