8H08
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8H07
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3Q53
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6U6Y
| Human SAMHD1 bound to ribo(CGCCU)-oligonucleotide | 分子名称: | 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, Deoxynucleoside triphosphate triphosphohydrolase SAMHD1, RNA CGCCU, ... | 著者 | Taylor, A.B, Bhattacharya, A, Wang, Z, Ivanov, D.N. | 登録日 | 2019-08-30 | 公開日 | 2020-09-02 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.47 Å) | 主引用文献 | Nucleic acid binding by SAMHD1 contributes to the antiretroviral activity and is enhanced by the GpsN modification. Nat Commun, 12, 2021
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3NXF
| Robust computational design, optimization, and structural characterization of retroaldol enzymes | 分子名称: | Retro-Aldolase, SULFATE ION | 著者 | Althoff, E.A, Jiang, L, Wang, L, Lassila, J.K, Moody, J, Bolduc, J, Wang, Z.Z, Smith, M, Hari, S, Herschlag, D, Stoddard, B.L, Baker, D. | 登録日 | 2010-07-13 | 公開日 | 2011-06-29 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Structural analyses of covalent enzyme-substrate analog complexes reveal strengths and limitations of de novo enzyme design. J.Mol.Biol., 415, 2012
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3O7R
| Crystal structure of Ru(p-cymene)/apo-H49AFr | 分子名称: | 1,2-ETHANEDIOL, CADMIUM ION, Ferritin light chain, ... | 著者 | Takezawa, Y, Bockmann, P, Sugi, N, Wang, Z, Abe, S, Murakami, T, Hikage, T, Erker, G, Watanabe, Y, Kitagawa, S, Ueno, T. | 登録日 | 2010-07-31 | 公開日 | 2011-04-20 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Incorporation of organometallic Ru complexes into apo-ferritin cage. J.CHEM.SOC.,DALTON TRANS., 40, 2011
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7L0R
| Structure of NTS-NTSR1-Gi complex in lipid nanodisc, noncanonical state, without AHD | 分子名称: | Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(T) subunit gamma-T1, Guanine nucleotide-binding protein G(i) subunit alpha-1, ... | 著者 | Zhang, M, Gui, M, Wang, Z, Gorgulla, C, Yu, J.J, Wu, H, Sun, Z, Klenk, C, Merklinger, L, Morstein, L, Hagn, F, Pluckthun, A, Brown, A, Nasr, M.L, Wagner, G. | 登録日 | 2020-12-12 | 公開日 | 2021-01-06 | 最終更新日 | 2021-03-24 | 実験手法 | ELECTRON MICROSCOPY (4.2 Å) | 主引用文献 | Cryo-EM structure of an activated GPCR-G protein complex in lipid nanodiscs. Nat.Struct.Mol.Biol., 28, 2021
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7L0Q
| Structure of NTS-NTSR1-Gi complex in lipid nanodisc, canonical state, with AHD | 分子名称: | Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(T) subunit gamma-T1, Guanine nucleotide-binding protein G(i) subunit alpha-1, ... | 著者 | Zhang, M, Gui, M, Wang, Z, Gorgulla, C, Yu, J.J, Wu, H, Sun, Z, Klenk, C, Merklinger, L, Morstein, L, Hagn, F, Pluckthun, A, Brown, A, Nasr, M.L, Wagner, G. | 登録日 | 2020-12-12 | 公開日 | 2021-01-06 | 最終更新日 | 2021-03-31 | 実験手法 | ELECTRON MICROSCOPY (4.3 Å) | 主引用文献 | Cryo-EM structure of an activated GPCR-G protein complex in lipid nanodiscs. Nat.Struct.Mol.Biol., 28, 2021
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3O7S
| Crystal structure of Ru(p-cymene)/apo-Fr | 分子名称: | 1,2-ETHANEDIOL, 1-methyl-4-(1-methylethyl)benzene, CADMIUM ION, ... | 著者 | Takezawa, Y, Bockmann, P, Sugi, N, Wang, Z, Abe, S, Murakami, T, Hikage, T, Erker, G, Watanabe, Y, Kitagawa, S, Ueno, T. | 登録日 | 2010-07-31 | 公開日 | 2011-04-20 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (1.73 Å) | 主引用文献 | Incorporation of organometallic Ru complexes into apo-ferritin cage. J.Chem.Soc.,Dalton Trans., 40, 2011
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7EVP
| Cryo-EM structure of the Gp168-beta-clamp complex | 分子名称: | Beta sliding clamp, Sliding clamp inhibitor | 著者 | Liu, B, Li, S, Liu, Y, Chen, H, Hu, Z, Wang, Z, Gou, L, Zhang, L, Ma, B, Wang, H, Matthews, S, Wang, Y, Zhang, K. | 登録日 | 2021-05-21 | 公開日 | 2022-02-16 | 最終更新日 | 2024-06-05 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Bacteriophage Twort protein Gp168 is a beta-clamp inhibitor by occupying the DNA sliding channel. Nucleic Acids Res., 49, 2021
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1PJP
| THE 2.2 A CRYSTAL STRUCTURE OF HUMAN CHYMASE IN COMPLEX WITH SUCCINYL-ALA-ALA-PRO-PHE-CHLOROMETHYLKETONE | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Chymase, SUCCINYL-ALA-ALA-PRO-PHE-CHLOROMETHYLKETONE INHIBITOR, ... | 著者 | Pereira, P.J.B, Wang, Z.M, Rubin, H, Huber, R, Bode, W, Schechter, N.M, Strobl, S. | 登録日 | 1998-09-07 | 公開日 | 1999-03-02 | 最終更新日 | 2024-04-24 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | The 2.2 A crystal structure of human chymase in complex with succinyl-Ala-Ala-Pro-Phe-chloromethylketone: structural explanation for its dipeptidyl carboxypeptidase specificity. J.Mol.Biol., 286, 1999
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1TIO
| HIGH PACKING DENSITY FORM OF BOVINE BETA-TRYPSIN IN CYCLOHEXANE | 分子名称: | BENZAMIDINE, CALCIUM ION, CYCLOHEXANE, ... | 著者 | Huang, Q, Zhu, G, Wang, Z, Tang, Q. | 登録日 | 1998-09-17 | 公開日 | 1998-09-23 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (1.93 Å) | 主引用文献 | X-ray studies on two forms of bovine beta-trypsin crystals in neat cyclohexane. Biochim.Biophys.Acta, 1429, 1998
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7L0P
| Structure of NTS-NTSR1-Gi complex in lipid nanodisc, canonical state, without AHD | 分子名称: | Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(T) subunit gamma-T1, Guanine nucleotide-binding protein G(i) subunit alpha-1, ... | 著者 | Zhang, M, Gui, M, Wang, Z, Gorgulla, C, Yu, J.J, Wu, H, Sun, Z, Klenk, C, Merklinger, L, Morstein, L, Hagn, F, Pluckthun, A, Brown, A, Nasr, M.L, Wagner, G. | 登録日 | 2020-12-12 | 公開日 | 2021-01-06 | 最終更新日 | 2021-03-24 | 実験手法 | ELECTRON MICROSCOPY (4.1 Å) | 主引用文献 | Cryo-EM structure of an activated GPCR-G protein complex in lipid nanodiscs. Nat.Struct.Mol.Biol., 28, 2021
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7L0S
| Structure of NTS-NTSR1-Gi complex in lipid nanodisc, noncanonical state, with AHD | 分子名称: | Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(T) subunit gamma-T1, Guanine nucleotide-binding protein G(i) subunit alpha-1, ... | 著者 | Zhang, M, Gui, M, Wang, Z, Gorgulla, C, Yu, J.J, Wu, H, Sun, Z, Klenk, C, Merklinger, L, Morstein, L, Hagn, F, Pluckthun, A, Brown, A, Nasr, M.L, Wagner, G. | 登録日 | 2020-12-12 | 公開日 | 2021-01-06 | 最終更新日 | 2021-03-24 | 実験手法 | ELECTRON MICROSCOPY (4.5 Å) | 主引用文献 | Cryo-EM structure of an activated GPCR-G protein complex in lipid nanodiscs. Nat.Struct.Mol.Biol., 28, 2021
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3Q52
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2VYA
| Crystal Structure of fatty acid amide hydrolase conjugated with the drug-like inhibitor PF-750 | 分子名称: | 4-(quinolin-3-ylmethyl)piperidine-1-carboxylic acid, CHLORIDE ION, FATTY-ACID AMIDE HYDROLASE 1, ... | 著者 | Mileni, M, Johnson, D.S, Wang, Z, Everdeen, D.S, Liimatta, M, Pabst, B, Bhattacharya, K, Nugent, R.A, Kamtekar, S, Cravatt, B.F, Ahn, K, Stevens, R.C. | 登録日 | 2008-07-22 | 公開日 | 2008-09-09 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.75 Å) | 主引用文献 | Structure-Guided Inhibitor Design for Human Faah by Interspecies Active Site Conversion. Proc.Natl.Acad.Sci.USA, 105, 2008
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3O6Y
| Robust computational design, optimization, and structural characterization of retroaldol enzymes | 分子名称: | Retro-Aldolase, SULFATE ION | 著者 | Althoff, E.A, Wang, L, Jiang, L, Moody, J, Bolduc, J, Lassila, J.K, Wang, Z.Z, Smith, M, Hari, S, Herschlag, D, Stoddard, B.L, Baker, D. | 登録日 | 2010-07-29 | 公開日 | 2011-06-29 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.091 Å) | 主引用文献 | Structural analyses of covalent enzyme-substrate analog complexes reveal strengths and limitations of de novo enzyme design. J.Mol.Biol., 415, 2012
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4N4R
| Structure basis of lipopolysaccharide biogenesis | 分子名称: | CACODYLATE ION, LPS-assembly lipoprotein LptE, LPS-assembly protein LptD, ... | 著者 | Dong, H, Xiang, Q, Wang, Z, Paterson, N.G, He, C, Zhang, Y, Wang, W, Dong, C. | 登録日 | 2013-10-08 | 公開日 | 2014-06-25 | 最終更新日 | 2014-07-16 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Structural basis for outer membrane lipopolysaccharide insertion. Nature, 511, 2014
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2HZ5
| Crystal structure of human dynein light chain Dnlc2A | 分子名称: | CESIUM ION, Dynein light chain 2A, cytoplasmic | 著者 | Liu, J.-F, Wang, Z.-X, Wang, X.-Q, Tang, Q, An, X.-M, Gui, L.-L, Liang, D.-C. | 登録日 | 2006-08-08 | 公開日 | 2007-08-14 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Crystal structure of human dynein light chain Dnlc2A: Structural insights into the interaction with IC74 Biochem.Biophys.Res.Commun., 349, 2006
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6LJG
| Crassostrea gigas ferritin mutant-D119G | 分子名称: | FE (III) ION, Ferritin | 著者 | Li, H, Zang, J, Tan, X, Wang, Z, Du, M. | 登録日 | 2019-12-15 | 公開日 | 2020-12-16 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.799 Å) | 主引用文献 | Crassostrea gigas ferritin mutant-D119G To Be Published
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6LIJ
| Crassostrea gigas ferritin | 分子名称: | Ferritin, MAGNESIUM ION | 著者 | Li, H, Zang, J, Tan, X, Wang, Z, Du, M. | 登録日 | 2019-12-11 | 公開日 | 2020-12-16 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Crassostrea gigas ferritin To Be Published
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6U6X
| Human SAMHD1 bound to deoxyribo(C*G*C*C*T)-oligonucleotide | 分子名称: | DNA SC-GS-SC-SC-DT, Deoxynucleoside triphosphate triphosphohydrolase SAMHD1, ZINC ION | 著者 | Taylor, A.B, Bhattacharya, A, Wang, Z, Ivanov, D.N. | 登録日 | 2019-08-30 | 公開日 | 2020-09-02 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.58 Å) | 主引用文献 | Nucleic acid binding by SAMHD1 contributes to the antiretroviral activity and is enhanced by the GpsN modification. Nat Commun, 12, 2021
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6A6H
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3VZB
| Crystal structure of Sphingosine Kinase 1 | 分子名称: | (2S,3R,4E)-2-aminooctadec-4-ene-1,3-diol, 1,2-ETHANEDIOL, SULFATE ION, ... | 著者 | Min, X, Walker, N.P, Wang, Z. | 登録日 | 2012-10-10 | 公開日 | 2013-05-08 | 最終更新日 | 2024-05-29 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Molecular basis of sphingosine kinase 1 substrate recognition and catalysis. Structure, 21, 2013
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7FAP
| Structure of VAR2CSA-CSA 3D7 | 分子名称: | 2-acetamido-2-deoxy-4-O-sulfo-beta-D-galactopyranose-(1-3)-beta-D-glucopyranuronic acid-(1-3)-2-acetamido-2-deoxy-4-O-sulfo-beta-D-galactopyranose-(1-4)-beta-D-glucopyranuronic acid-(1-3)-2-acetamido-2-deoxy-4-O-sulfo-beta-D-galactopyranose-(1-4)-beta-D-glucopyranuronic acid-(1-3)-2-acetamido-2-deoxy-4-O-sulfo-beta-D-galactopyranose-(1-4)-beta-D-glucopyranuronic acid-(1-3)-2-acetamido-2-deoxy-4-O-sulfo-beta-D-galactopyranose-(1-4)-beta-D-glucopyranuronic acid-(1-3)-2-acetamido-2-deoxy-4-O-sulfo-beta-D-galactopyranose-(1-4)-beta-D-glucopyranuronic acid, Erythrocyte membrane protein 1, PfEMP1 | 著者 | Wang, L, Wang, Z. | 登録日 | 2021-07-07 | 公開日 | 2022-05-04 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | The molecular mechanism of cytoadherence to placental or tumor cells through VAR2CSA from Plasmodium falciparum. Cell Discov, 7, 2021
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