3NXF
Robust computational design, optimization, and structural characterization of retroaldol enzymes
Summary for 3NXF
Entry DOI | 10.2210/pdb3nxf/pdb |
Related | 3O6Y 3UD6 |
Descriptor | Retro-Aldolase, SULFATE ION (3 entities in total) |
Functional Keywords | computationally designed, retroaldolase, tim barrel, lyase |
Biological source | artificial gene |
Total number of polymer chains | 1 |
Total formula weight | 29931.47 |
Authors | Althoff, E.A.,Jiang, L.,Wang, L.,Lassila, J.K.,Moody, J.,Bolduc, J.,Wang, Z.Z.,Smith, M.,Hari, S.,Herschlag, D.,Stoddard, B.L.,Baker, D. (deposition date: 2010-07-13, release date: 2011-06-29, Last modification date: 2023-09-06) |
Primary citation | Wang, L.,Althoff, E.A.,Bolduc, J.,Jiang, L.,Moody, J.,Lassila, J.K.,Giger, L.,Hilvert, D.,Stoddard, B.,Baker, D. Structural analyses of covalent enzyme-substrate analog complexes reveal strengths and limitations of de novo enzyme design. J.Mol.Biol., 415:615-625, 2012 Cited by PubMed: 22075445DOI: 10.1016/j.jmb.2011.10.043 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.4 Å) |
Structure validation
Download full validation report