7FAP

Structure of VAR2CSA-CSA 3D7

Summary for 7FAP

• Entry DOI: 10.2210/pdb7fap/pdb
• EMDB information: 31504
• Descriptor: Erythrocyte membrane protein 1, PfEMP1, 2-acetamido-2-deoxy-4-O-sulfo-beta-D-galactopyranose-(1-3)-beta-D-glucopyranuronic acid-(1-3)-2-acetamido-2-deoxy-4-O-sulfo-beta-D-galactopyranose-(1-4)-beta-D-glucopyranuronic acid-(1-3)-2-acetamido-2-deoxy-4-O-sulfo-beta-D-galactopyranose-(1-4)-beta-D-glucopyranuronic acid-(1-3)-2-acetamido-2-deoxy-4-O-sulfo-beta-D-galactopyranose-(1-4)-beta-D-glucopyranuronic acid-(1-3)-2-acetamido-2-deoxy-4-O-sulfo-beta-D-galactopyranose-(1-4)-beta-D-glucopyranuronic acid-(1-3)-2-acetamido-2-deoxy-4-O-sulfo-beta-D-galactopyranose-(1-4)-beta-D-glucopyranuronic acid (2 entities in total)
• Functional Keywords: plasmodium falciparum, complex, csa binding, cell adhesion
• Biological source: Plasmodium falciparum 3D7
• Total number of polymer chains: 1
• Total formula weight: 308964.51

Authors

Wang, L.,Wang, Z. (deposition date: 2021-07-07, release date: 2022-05-04, Last modification date: 2024-10-09)

• Primary citation: Wang, W.,Wang, Z.,Yang, X.,Gao, Y.,Zhang, X.,Cao, L.,Dai, A.,Sun, J.,Sun, L.,Jiang, L.,Chen, Z.,Wang, L.; The molecular mechanism of cytoadherence to placental or tumor cells through VAR2CSA from Plasmodium falciparum.; Cell Discov, 7:94-94, 2021; PubMed: 34663782; DOI: 10.1038/s41421-021-00324-8

Experimental method

ELECTRON MICROSCOPY (3.4 Å)