7L0R

Structure of NTS-NTSR1-Gi complex in lipid nanodisc, noncanonical state, without AHD

Summary for 7L0R

Entry DOI	10.2210/pdb7l0r/pdb
EMDB information	23099 23100 23101
Descriptor	Neurotensin receptor type 1, Neurotensin, Guanine nucleotide-binding protein G(i) subunit alpha-1, ... (5 entities in total)
Functional Keywords	gpcr, ntsr1, nts, g protein, nanodisc, signaling protein
Biological source	Rattus norvegicus (Rat) More
Total number of polymer chains	5
Total formula weight	128562.06
Authors	Zhang, M.,Gui, M.,Wang, Z.,Gorgulla, C.,Yu, J.J.,Wu, H.,Sun, Z.,Klenk, C.,Merklinger, L.,Morstein, L.,Hagn, F.,Pluckthun, A.,Brown, A.,Nasr, M.L.,Wagner, G. (deposition date: 2020-12-12, release date: 2021-01-06, Last modification date: 2021-03-24)
Primary citation	Zhang, M.,Gui, M.,Wang, Z.F.,Gorgulla, C.,Yu, J.J.,Wu, H.,Sun, Z.J.,Klenk, C.,Merklinger, L.,Morstein, L.,Hagn, F.,Pluckthun, A.,Brown, A.,Nasr, M.L.,Wagner, G. Cryo-EM structure of an activated GPCR-G protein complex in lipid nanodiscs. Nat.Struct.Mol.Biol., 28:258-267, 2021 Cited by PubMed: 33633398 DOI: 10.1038/s41594-020-00554-6 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (4.2 Å)

Structure validation