7L0Q

Structure of NTS-NTSR1-Gi complex in lipid nanodisc, canonical state, with AHD

Summary for 7L0Q

• Entry DOI: 10.2210/pdb7l0q/pdb
• Related: 7L0P
• EMDB information: 23099 23100
• Descriptor: Neurotensin receptor type 1, Neurotensin, Guanine nucleotide-binding protein G(i) subunit alpha-1, ... (5 entities in total)
• Functional Keywords: gpcr, ntsr1, nts, g protein, nanodisc, signaling protein
• Biological source: Rattus norvegicus (Rat); More
• Total number of polymer chains: 5
• Total formula weight: 128562.06

Authors

Zhang, M.,Gui, M.,Wang, Z.,Gorgulla, C.,Yu, J.J.,Wu, H.,Sun, Z.,Klenk, C.,Merklinger, L.,Morstein, L.,Hagn, F.,Pluckthun, A.,Brown, A.,Nasr, M.L.,Wagner, G. (deposition date: 2020-12-12, release date: 2021-01-06, Last modification date: 2021-03-31)

• Primary citation: Zhang, M.,Gui, M.,Wang, Z.F.,Gorgulla, C.,Yu, J.J.,Wu, H.,Sun, Z.J.,Klenk, C.,Merklinger, L.,Morstein, L.,Hagn, F.,Pluckthun, A.,Brown, A.,Nasr, M.L.,Wagner, G.; Cryo-EM structure of an activated GPCR-G protein complex in lipid nanodiscs.; Nat.Struct.Mol.Biol., 28:258-267, 2021; PubMed: 33633398; DOI: 10.1038/s41594-020-00554-6

Experimental method

ELECTRON MICROSCOPY (4.3 Å)