7L0P
Structure of NTS-NTSR1-Gi complex in lipid nanodisc, canonical state, without AHD
Summary for 7L0P
Entry DOI | 10.2210/pdb7l0p/pdb |
EMDB information | 23099 |
Descriptor | Neurotensin receptor type 1, Neurotensin, Guanine nucleotide-binding protein G(i) subunit alpha-1, ... (5 entities in total) |
Functional Keywords | gpcr, ntsr1, nts, g protein, nanodisc, signaling protein |
Biological source | Rattus norvegicus (Rat) More |
Total number of polymer chains | 5 |
Total formula weight | 128562.06 |
Authors | Zhang, M.,Gui, M.,Wang, Z.,Gorgulla, C.,Yu, J.J.,Wu, H.,Sun, Z.,Klenk, C.,Merklinger, L.,Morstein, L.,Hagn, F.,Pluckthun, A.,Brown, A.,Nasr, M.L.,Wagner, G. (deposition date: 2020-12-12, release date: 2021-01-06, Last modification date: 2021-03-24) |
Primary citation | Zhang, M.,Gui, M.,Wang, Z.F.,Gorgulla, C.,Yu, J.J.,Wu, H.,Sun, Z.J.,Klenk, C.,Merklinger, L.,Morstein, L.,Hagn, F.,Pluckthun, A.,Brown, A.,Nasr, M.L.,Wagner, G. Cryo-EM structure of an activated GPCR-G protein complex in lipid nanodiscs. Nat.Struct.Mol.Biol., 28:258-267, 2021 Cited by PubMed: 33633398DOI: 10.1038/s41594-020-00554-6 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (4.1 Å) |
Structure validation
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