6C6L
 
 | | Yeast Vacuolar ATPase Vo in lipid nanodisc | | 分子名称: | V-type proton ATPase subunit a, vacuolar isoform, V-type proton ATPase subunit c, ... | | 著者 | Roh, S, Stam, N.J, Hryc, C, Couoh-Cardel, S, Pintilie, G, Chiu, W, Wilkens, S. | | 登録日 | 2018-01-19 | | 公開日 | 2018-03-21 | | 最終更新日 | 2024-03-13 | | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | | 主引用文献 | The 3.5- angstrom CryoEM Structure of Nanodisc-Reconstituted Yeast Vacuolar ATPase VoProton Channel.
Mol. Cell, 69, 2018
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4RLN
 | | Hen egg-white lysozyme solved from serial crystallography at a synchrotron source, data processed with nXDS | | 分子名称: | Lysozyme C | | 著者 | Botha, S, Nass, K, Barends, T, Kabsch, W, Latz, B, Dworkowski, F, Foucar, L, Panepucci, E, Wang, M, Shoeman, R, Schlichting, I, Doak, R.B. | | 登録日 | 2014-10-17 | | 公開日 | 2015-02-25 | | 最終更新日 | 2024-11-06 | | 実験手法 | X-RAY DIFFRACTION (2.17 Å) | | 主引用文献 | Room-temperature serial crystallography at synchrotron X-ray sources using slowly flowing free-standing high-viscosity microstreams.
Acta Crystallogr.,Sect.D, 71, 2015
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6C7K
 | | Crystal structure of an ACO/RPE65 chimera | | 分子名称: | Apocarotenoid-15,15'-oxygenase, CHLORIDE ION, FE (II) ION | | 著者 | Kiser, P.D, Shi, W. | | 登録日 | 2018-01-22 | | 公開日 | 2018-04-25 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Insights into the pathogenesis of dominant retinitis pigmentosa associated with a D477G mutation in RPE65.
Hum.Mol.Genet., 27, 2018
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5UGT
 | | Crystal structure of M. tuberculosis InhA inhibited by PT504 | | 分子名称: | 2-(2-chloranylphenoxy)-5-[(4-cyclopropyl-1,2,3-triazol-1-yl)methyl]phenol, Enoyl-[acyl-carrier-protein] reductase [NADH], NICOTINAMIDE-ADENINE-DINUCLEOTIDE | | 著者 | Eltschkner, S, Pschibul, A, Spagnuolo, L.A, Yu, W, Tonge, P.J, Kisker, C. | | 登録日 | 2017-01-10 | | 公開日 | 2017-02-15 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Evaluating the Contribution of Transition-State Destabilization to Changes in the Residence Time of Triazole-Based InhA Inhibitors.
J. Am. Chem. Soc., 139, 2017
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6C2U
 | | Solution structure of a phosphate-loop protein | | 分子名称: | phosphate-loop protein | | 著者 | Yang, F, Yang, W, Lin, Y.R, Romero Romero, M.L, Tawfik, D, Baker, D, Varani, G. | | 登録日 | 2018-01-09 | | 公開日 | 2018-11-21 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Simple yet functional phosphate-loop proteins.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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6C8M
 | | RNA-activated 2-AIpG monomer, 1.5h soaking | | 分子名称: | 2-amino-1-[(R)-{[(2R,3S,4R,5R)-5-(2-amino-6-oxo-1,6-dihydro-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}(hydroxy)phosphoryl]-3-[(S)-{[(2R,3S,4R,5R)-5-(2-amino-6-oxo-1,6-dihydro-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}(hydroxy)phosphoryl]-1H-imidazol-3-ium, 5'-O-[(R)-(2-amino-1H-imidazol-1-yl)(hydroxy)phosphoryl]guanosine, RNA (5'-R(*(LCC)P*(LCC)P*(LCC)P*(LCG)P*AP*CP*UP*UP*AP*AP*GP*UP*CP*G)-3'), ... | | 著者 | Zhang, W, Szostak, J.W. | | 登録日 | 2018-01-25 | | 公開日 | 2018-05-30 | | 最終更新日 | 2024-05-01 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Crystallographic observation of nonenzymatic RNA primer extension.
Elife, 7, 2018
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5UHY
 | | A Human Antibody Against Zika Virus Crosslinks the E Protein to Prevent Infection | | 分子名称: | ZV67 Fab chain 1, ZV67 Fab chain 2, envelope protein | | 著者 | Hasan, S.S, Miller, A, Sapparapu, G, Fernandez, E, Klose, T, Long, F, Fokine, A, Porta, J.C, Jiang, W, Diamond, M.S, Crowe Jr, J.E, Kuhn, R.J, Rossmann, M.G. | | 登録日 | 2017-01-12 | | 公開日 | 2017-03-29 | | 最終更新日 | 2024-11-13 | | 実験手法 | ELECTRON MICROSCOPY (6.2 Å) | | 主引用文献 | A human antibody against Zika virus crosslinks the E protein to prevent infection.
Nat Commun, 8, 2017
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5UHC
 | | Crystal structure of Mycobacterium tuberculosis transcription initiation complex containing 3nt RNA in complex with Rifampin | | 分子名称: | DNA (5'-D(*CP*AP*TP*CP*CP*GP*TP*GP*AP*GP*TP*CP*CP*AP*GP*G)-3'), DNA (5'-D(*TP*AP*TP*AP*AP*TP*GP*GP*GP*AP*GP*CP*TP*GP*TP*CP*AP*CP*GP*GP*AP*TP*G)-3'), DNA-directed RNA polymerase subunit alpha, ... | | 著者 | Lin, W, Das, K, Feng, Y, Ebright, R.H. | | 登録日 | 2017-01-11 | | 公開日 | 2017-04-12 | | 最終更新日 | 2024-10-09 | | 実験手法 | X-RAY DIFFRACTION (3.796 Å) | | 主引用文献 | Structural Basis of Mycobacterium tuberculosis Transcription and Transcription Inhibition.
Mol. Cell, 66, 2017
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2NWA
 | | X-ray Crystal Structure of Protein ytmB from Bacillus subtilis. Northeast Structural Genomics Consortium Target SR466 | | 分子名称: | Hypothetical protein ytmB, SULFATE ION | | 著者 | Zhou, W, Forouhar, F, Seetharaman, J, Wang, D, Cunningham, K, Ma, L.-C, Fang, Y, Xiao, R, Baran, M.C, Acton, T.B, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG) | | 登録日 | 2006-11-14 | | 公開日 | 2007-01-09 | | 最終更新日 | 2024-10-16 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Crystal Structure of the Hypothetical protein YtmB from Bacillus subtilis subsp. (subtilis str. 168), Northeast Structural Genomics target SR466
To be Published
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5UH7
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5UHD
 | | Crystal structure of Mycobacterium tuberculosis transcription initiation complex containing 4nt RNA in complex with Rifampin | | 分子名称: | DNA (5'-D(*CP*AP*TP*CP*CP*GP*TP*GP*AP*GP*TP*CP*GP*AP*GP*G)-3'), DNA (5'-D(*TP*AP*TP*AP*AP*TP*GP*GP*GP*AP*GP*CP*TP*GP*TP*CP*AP*CP*GP*GP*AP*TP*G)-3'), DNA-directed RNA polymerase subunit alpha, ... | | 著者 | Lin, W, Das, K, Feng, Y, Ebright, R.H. | | 登録日 | 2017-01-11 | | 公開日 | 2017-04-12 | | 最終更新日 | 2024-10-16 | | 実験手法 | X-RAY DIFFRACTION (4.01 Å) | | 主引用文献 | Structural Basis of Mycobacterium tuberculosis Transcription and Transcription Inhibition.
Mol. Cell, 66, 2017
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6JAW
 | | Crystal structure of Ostrinia furnacalis Group II chitinase catalytic domain 1 in complex with a napthalimide derivative | | 分子名称: | 2-[3-(morpholin-4-yl)propyl]-1H-benzo[de]isoquinoline-1,3(2H)-dione, 2-acetamido-2-deoxy-beta-D-glucopyranose, Group II chitinase | | 著者 | Chen, W, Zhou, Y, Yang, Q. | | 登録日 | 2019-01-25 | | 公開日 | 2019-05-15 | | 最終更新日 | 2024-10-16 | | 実験手法 | X-RAY DIFFRACTION (1.981 Å) | | 主引用文献 | Structural dissection reveals a general mechanistic principle for group II chitinase (ChtII) inhibition.
J.Biol.Chem., 294, 2019
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5UH5
 | | Crystal structure of Mycobacterium tuberculosis transcription initiation complex containing 3 nt of RNA | | 分子名称: | DNA (5'-D(*CP*AP*TP*CP*CP*GP*TP*GP*AP*GP*TP*CP*CP*AP*GP*G)-3'), DNA (5'-D(*TP*AP*TP*AP*AP*TP*GP*GP*GP*AP*GP*CP*TP*GP*TP*CP*AP*CP*GP*GP*AP*TP*G)-3'), DNA-directed RNA polymerase subunit alpha, ... | | 著者 | Lin, W, Das, K, Feng, Y, Ebright, R.H. | | 登録日 | 2017-01-10 | | 公開日 | 2017-04-12 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (3.746 Å) | | 主引用文献 | Structural Basis of Mycobacterium tuberculosis Transcription and Transcription Inhibition.
Mol. Cell, 66, 2017
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6BSQ
 | | Enterococcus faecalis Penicillin Binding Protein 4 (PBP4) | | 分子名称: | CHLORIDE ION, GLYCEROL, PBP4 protein | | 著者 | Moon, T.M, D'Andrea, E.D, Peti, W, Page, R. | | 登録日 | 2017-12-04 | | 公開日 | 2018-10-31 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | The structures of penicillin-binding protein 4 (PBP4) and PBP5 fromEnterococciprovide structural insights into beta-lactam resistance.
J. Biol. Chem., 293, 2018
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6JE9
 | | Crystal structure of Nme1Cas9-sgRNA dimer mediated by double protein inhibitor AcrIIC3 monomers | | 分子名称: | AcrIIC3, CRISPR-associated endonuclease Cas9, sgRNA | | 著者 | Sun, W, Yang, J, Cheng, Z, Liu, C, Wang, K, Huang, X, Wang, Y. | | 登録日 | 2019-02-04 | | 公開日 | 2019-11-06 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (3.46 Å) | | 主引用文献 | Structures of Neisseria meningitidis Cas9 Complexes in Catalytically Poised and Anti-CRISPR-Inhibited States.
Mol.Cell, 76, 2019
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3HTQ
 | | the hemagglutinin structure of an avian H1N1 influenza A virus in complex with LSTc | | 分子名称: | 2-acetamido-2-deoxy-alpha-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin, ... | | 著者 | Wang, G, Li, A, Zhang, Q, Wu, C, Zhang, R, Cai, Q, Song, W, Yuen, K.-Y. | | 登録日 | 2009-06-12 | | 公開日 | 2009-08-11 | | 最終更新日 | 2024-11-13 | | 実験手法 | X-RAY DIFFRACTION (2.955 Å) | | 主引用文献 | The hemagglutinin structure of an avian H1N1 influenza A virus
Virology, 392, 2009
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4PIW
 | | Crystal structure of sugar aminotransferase WecE from Escherichia coli K-12 | | 分子名称: | TDP-4-keto-6-deoxy-D-glucose transaminase family protein | | 著者 | Wang, F, Xu, W, Helmich, K.E, Singh, S, Yennamalli, R.M, Miller, M.D, Bingman, C.A, Thorson, J.S, Phillips Jr, G.N, Enzyme Discovery for Natural Product Biosynthesis (NatPro) | | 登録日 | 2014-05-09 | | 公開日 | 2014-07-16 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Crystal structure of sugar aminotransferase WecE from Escherichia coli K-12
To Be Published
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2O1E
 | | Crystal Structure of the Metal-dependent Lipoprotein YcdH from Bacillus subtilis, Northeast Structural Genomics Target SR583 | | 分子名称: | MANGANESE (II) ION, YcdH | | 著者 | Forouhar, F, Zhou, W, Seetharaman, J, Chen, C.X, Fang, Y, Cunningham, K, Ma, L.-C, Janjua, H, Xiao, R, Baran, M.C, Liu, J, Acton, T.B, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG) | | 登録日 | 2006-11-28 | | 公開日 | 2006-12-12 | | 最終更新日 | 2024-11-06 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Crystal Structure of the Metal-dependent Lipoprotein YcdH from Bacillus subtilis, Northeast Structural Genomics Target SR583
To be Published
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3HXI
 | | Crystal structure of Schistosome eIF4E complexed with m7GpppG and 4E-BP | | 分子名称: | 7-METHYL-GUANOSINE-5'-TRIPHOSPHATE-5'-GUANOSINE, Eukaryotic Translation Initiation 4E, Eukaryotic translation initiation factor 4E-binding protein 1 | | 著者 | Liu, W, Zhao, R, Jones, D.N.M, Davis, R.E. | | 登録日 | 2009-06-20 | | 公開日 | 2009-08-25 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Structural insights into parasite EIF4E binding specificity for m7G and m2,2,7G mRNA cap.
J.Biol.Chem., 284, 2009
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6BY9
 | | Crystal structure of EHMT1 | | 分子名称: | Histone-lysine N-methyltransferase EHMT1, UNKNOWN ATOM OR ION | | 著者 | Dong, A, Wei, Y, Li, A, Tempel, W, Han, S, Sunnerhagen, M, Penn, L, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Tong, Y, Structural Genomics Consortium (SGC) | | 登録日 | 2017-12-20 | | 公開日 | 2018-01-31 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Crystal structure of EHMT1
to be published
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2O6U
 | | Crystal structure of the PA5185 protein from Pseudomonas Aeruginosa strain PAO1- new crystal form. | | 分子名称: | THIOESTERASE | | 著者 | Chruszcz, M, Koclega, K.D, Evdokimova, E, Cymborowski, M, Kudritska, M, Savchenko, A, Edwards, A, Minor, W. | | 登録日 | 2006-12-08 | | 公開日 | 2007-12-11 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (3.01 Å) | | 主引用文献 | Function-biased choice of additives for optimization of protein crystallization - the case of the putative thioesterase PA5185 from Pseudomonas aeruginosa PAO1.
Cryst.Growth Des., 8, 2008
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2O6T
 | | Crystal structure of the PA5185 protein from Pseudomonas Aeruginosa strain PAO1- orthorhombic form (P2221). | | 分子名称: | CHLORIDE ION, THIOESTERASE | | 著者 | Chruszcz, M, Koclega, K.D, Evdokimova, E, Cymborowski, M, Kudritska, M, Savchenko, A, Edwards, A, Minor, W. | | 登録日 | 2006-12-08 | | 公開日 | 2007-12-11 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.55 Å) | | 主引用文献 | Function-biased choice of additives for optimization of protein crystallization - the case of the putative thioesterase PA5185 from Pseudomonas aeruginosa PAO1.
Cryst.Growth Des., 8, 2008
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5JNC
 | | Crystal structure for the complex of human carbonic anhydrase IV and 4-aminomethylbenzene sulfonamide | | 分子名称: | 4-(aminomethyl)benzene-1-sulfonamide, ACETATE ION, Carbonic anhydrase 4, ... | | 著者 | Chen, Z, Waheed, A, Di Cera, E, Sly, W.S. | | 登録日 | 2016-04-29 | | 公開日 | 2017-05-03 | | 最終更新日 | 2024-11-13 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Intrinsic thermodynamics of high affinity inhibitor binding to recombinant human carbonic anhydrase IV.
Eur. Biophys. J., 47, 2018
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4P8X
 | | The crystal structures of YKL-39 in the presence of chitooligosaccharides (GlcNAc6) were solved to resolutions of 2.48 angstrom | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Chitinase-3-like protein 2, SULFATE ION | | 著者 | Suginta, W, Ranok, A, Robinson, R.C, Wongsantichon, J. | | 登録日 | 2014-04-01 | | 公開日 | 2014-12-03 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (2.48 Å) | | 主引用文献 | Structural and Thermodynamic Insights into Chitooligosaccharide Binding to Human Cartilage Chitinase 3-like Protein 2 (CHI3L2 or YKL-39).
J.Biol.Chem., 290, 2015
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3I4A
 | | Crystal structure of dimethylarginine dimethylaminohydrolase-1 (DDAH-1) in complex with N5-(1-iminopropyl)-L-ornithine | | 分子名称: | N(G),N(G)-dimethylarginine dimethylaminohydrolase 1, N5-(1-iminopropyl)-L-ornithine | | 著者 | Monzingo, A.F, Wang, Y, Hu, S, Schaller, T.H, Fast, W, Robertus, J.D. | | 登録日 | 2009-07-01 | | 公開日 | 2009-08-25 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (1.898 Å) | | 主引用文献 | Developing dual and specific inhibitors of dimethylarginine dimethylaminohydrolase-1 and nitric oxide synthase: toward a targeted polypharmacology to control nitric oxide.
Biochemistry, 48, 2009
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