6DTF
| Crystal structure of Haemophilus influenzae OppA complex with KKK | Descriptor: | LYS-LYS-LYS, Periplasmic oligopeptide-binding protein, SULFATE ION | Authors: | Tanaka, K.J, Pinkett, H.W. | Deposit date: | 2018-06-16 | Release date: | 2018-11-28 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Oligopeptide-binding protein from nontypeableHaemophilus influenzaehas ligand-specific sites to accommodate peptides and heme in the binding pocket. J. Biol. Chem., 294, 2019
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6DVO
| Crystal structure of Danio rerio histone deacetylase 6 catalytic domain 2 in complex with Bavarostat | Descriptor: | 1,2-ETHANEDIOL, 3-fluoro-N-hydroxy-4-[(methyl{[(3s,5s,7s)-tricyclo[3.3.1.1~3,7~]decan-1-yl]methyl}amino)methyl]benzamide, Hdac6 protein, ... | Authors: | Porter, N.J, Christianson, D.W. | Deposit date: | 2018-06-24 | Release date: | 2018-08-29 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.98 Å) | Cite: | Histone Deacetylase 6-Selective Inhibitors and the Influence of Capping Groups on Hydroxamate-Zinc Denticity. J. Med. Chem., 61, 2018
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6DP0
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6DPJ
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6DHW
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8S9W
| Murine S100A7/S100A15 in presence of calcium | Descriptor: | ACETATE ION, CALCIUM ION, GLYCEROL, ... | Authors: | Harrison, S.A, Naretto, A, Balakrishnan, S, Chazin, W.J. | Deposit date: | 2023-03-30 | Release date: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.69 Å) | Cite: | Comparative analysis of the physical properties of murine and human S100A7: Insight into why zinc piracy is mediated by human but not murine S100A7. J.Biol.Chem., 299, 2023
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6D4O
| Eubacterium eligens beta-glucuronidase bound to an amoxapine-glucuronide conjugate | Descriptor: | (5aR,9aR)-2-chloro-11-(4-beta-D-glucopyranuronosylpiperazin-1-yl)-5a,6,9,9a-tetrahydrodibenzo[b,f][1,4]oxazepine, Beta-glucuronidase, CHLORIDE ION, ... | Authors: | Pellock, S.J, Walton, W.G, Redinbo, M.R. | Deposit date: | 2018-04-18 | Release date: | 2018-07-25 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Gut Microbial beta-Glucuronidase Inhibition via Catalytic Cycle Interception. ACS Cent Sci, 4, 2018
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8SCZ
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6DEM
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8SD0
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6DI6
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8SR6
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6DB0
| N-Terminal bromodomain of Human BRD2 with a Tetrahydroquinoline analogue | Descriptor: | 1,2-ETHANEDIOL, 1-[(2S,4R)-4-[(2-chlorophenyl)amino]-2-methyl-6-(1H-pyrazol-3-yl)-3,4-dihydroquinolin-1(2H)-yl]ethan-1-one, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ... | Authors: | White, S.W, Yun, M. | Deposit date: | 2018-05-02 | Release date: | 2019-11-13 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | N-Terminal bromodomain of Human BRD2 with a Tetrahydroquinoline analogue To Be Published
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6DBC
| Second bromodomain of Human BRD2 with a Tetrahydroquinoline analogue | Descriptor: | 1,2-ETHANEDIOL, 1-[(2S,4R)-4-[(2-chlorophenyl)amino]-2-methyl-6-(1H-pyrazol-3-yl)-3,4-dihydroquinolin-1(2H)-yl]ethan-1-one, Bromodomain-containing protein 2 | Authors: | White, S.W, Yun, M. | Deposit date: | 2018-05-03 | Release date: | 2019-11-13 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.05 Å) | Cite: | Second bromodomain of Human BRD2 with a Tetrahydroquinoline analogue To Be Published
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6DOK
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6DOY
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6DQT
| Crystal structure of Haemophilus influenzae OppA complex with LGG | Descriptor: | ACETATE ION, LEU-GLY-GLY, Periplasmic oligopeptide-binding protein, ... | Authors: | Tanaka, K.J, Pinkett, H.W. | Deposit date: | 2018-06-11 | Release date: | 2018-11-28 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Oligopeptide-binding protein from nontypeableHaemophilus influenzaehas ligand-specific sites to accommodate peptides and heme in the binding pocket. J. Biol. Chem., 294, 2019
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8SEI
| SF Tau from Down Syndrome | Descriptor: | Microtubule-associated protein tau | Authors: | Hoq, M.R, Bharath, S.R, Jiang, W, Vago, F.S, Bharath, S.R. | Deposit date: | 2023-04-10 | Release date: | 2024-04-03 | Last modified: | 2024-06-26 | Method: | ELECTRON MICROSCOPY (2.9 Å) | Cite: | Cryo-EM structures of amyloid-beta and tau filaments in Down syndrome. Nat.Struct.Mol.Biol., 31, 2024
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6DSS
| Re-refinement of P. falciparum orotidine 5'-monophosphate decarboxylase | Descriptor: | Orotidine 5'-monophosphate decarboxylase, URIDINE-5'-MONOPHOSPHATE | Authors: | Brandt, G.S, Novak, W.R.P. | Deposit date: | 2018-06-14 | Release date: | 2018-10-17 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.599 Å) | Cite: | Re-refinement of Plasmodium falciparum orotidine 5'-monophosphate decarboxylase provides a clearer picture of an important malarial drug target. Acta Crystallogr F Struct Biol Commun, 74, 2018
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8SEH
| PHF Tau from Down Syndrome | Descriptor: | Microtubule-associated protein tau | Authors: | Hoq, M.R, Bharath, S.R, Jiang, W, Vago, F.S. | Deposit date: | 2023-04-10 | Release date: | 2024-04-03 | Last modified: | 2024-06-26 | Method: | ELECTRON MICROSCOPY (2.9 Å) | Cite: | Cryo-EM structures of amyloid-beta and tau filaments in Down syndrome. Nat.Struct.Mol.Biol., 31, 2024
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8SEK
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8SEL
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6D79
| Structure of CysZ, a sulfate permease from Pseudomonas Fragi | Descriptor: | Sulfate transporter CysZ | Authors: | Sanghai, Z.A, Liu, Q, Clarke, O.B, Banerjee, S, Rajashankar, K.R, Hendrickson, W.A, Mancia, F. | Deposit date: | 2018-04-24 | Release date: | 2018-05-16 | Last modified: | 2020-01-01 | Method: | X-RAY DIFFRACTION (3.501 Å) | Cite: | Structure-based analysis of CysZ-mediated cellular uptake of sulfate. Elife, 7, 2018
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8SEJ
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6DP7
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