6D4O

Eubacterium eligens beta-glucuronidase bound to an amoxapine-glucuronide conjugate

Summary for 6D4O

• Entry DOI: 10.2210/pdb6d4o/pdb
• Descriptor: Beta-glucuronidase, (5aR,9aR)-2-chloro-11-(4-beta-D-glucopyranuronosylpiperazin-1-yl)-5a,6,9,9a-tetrahydrodibenzo[b,f][1,4]oxazepine, CHLORIDE ION, ... (5 entities in total)
• Functional Keywords: glycosyl hydrolase, hydrolase
• Biological source: [Eubacterium] eligens
• Total number of polymer chains: 1
• Total formula weight: 70387.50

Authors

Pellock, S.J.,Walton, W.G.,Redinbo, M.R. (deposition date: 2018-04-18, release date: 2018-07-25, Last modification date: 2024-03-13)

• Primary citation: Pellock, S.J.,Creekmore, B.C.,Walton, W.G.,Mehta, N.,Biernat, K.A.,Cesmat, A.P.,Ariyarathna, Y.,Dunn, Z.D.,Li, B.,Jin, J.,James, L.I.,Redinbo, M.R.; Gut Microbial beta-Glucuronidase Inhibition via Catalytic Cycle Interception.; ACS Cent Sci, 4:868-879, 2018; PubMed: 30062115; DOI: 10.1021/acscentsci.8b00239

Experimental method

X-RAY DIFFRACTION (2.9 Å)