6DP0
Crystal Structure of Bacillus Halodurans Ribonuclease H1 in Complex with an RNA/DNA Hybrid: Reaction in 2.5 mM Mg2+ and 75 mM K+ for 40 s at 21 C
Summary for 6DP0
Entry DOI | 10.2210/pdb6dp0/pdb |
Group deposition | Cleavage of RNA by B. Halodurans Ribonuclease H1 (G_1001001) |
Descriptor | Ribonuclease H, 5'-R(*AP*CP*AP*U)-3' portion of uncleaved RNA 5'-R(*AP*CP*AP*UP*CP*G)-3', 5'-R(P*CP*G)-3' portion of uncleaved RNA 5'-R(*AP*CP*AP*UP*CP*G)-3', ... (10 entities in total) |
Functional Keywords | protein-rna-dna complex, rna hydrolysis, in crystallo catalysis, metal dependent catalysis, hydrolase-dna-rna complex, hydrolase/dna/rna |
Biological source | Bacillus halodurans (strain ATCC BAA-125 / DSM 18197 / FERM 7344 / JCM 9153 / C-125) More |
Total number of polymer chains | 4 |
Total formula weight | 20368.94 |
Authors | Samara, N.L.,Yang, W. (deposition date: 2018-06-09, release date: 2018-08-15, Last modification date: 2023-10-11) |
Primary citation | Samara, N.L.,Yang, W. Cation trafficking propels RNA hydrolysis. Nat. Struct. Mol. Biol., 25:715-721, 2018 Cited by PubMed: 30076410DOI: 10.1038/s41594-018-0099-4 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.451 Å) |
Structure validation
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