8UHA
 
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8UI0
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8UHG
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4TMA
 | | Crystal structure of gyrase bound to its inhibitor YacG | | 分子名称: | DNA gyrase inhibitor YacG, DNA gyrase subunit A, DNA gyrase subunit B, ... | | 著者 | Vos, S.M, Lyubimov, A.Y, Hershey, D.M, Schoeffler, A.J, Berger, J.M. | | 登録日 | 2014-05-31 | | 公開日 | 2014-07-23 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | | 主引用文献 | Direct control of type IIA topoisomerase activity by a chromosomally encoded regulatory protein.
Genes Dev., 28, 2014
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4MN4
 | | Structural Basis for the MukB-topoisomerase IV Interaction | | 分子名称: | Chromosome partition protein MukB, DNA topoisomerase 4 subunit A | | 著者 | Vos, S.M, Stewart, N.K, Oakley, M.G, Berger, J.M. | | 登録日 | 2013-09-09 | | 公開日 | 2013-10-23 | | 最終更新日 | 2023-12-06 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Structural basis for the MukB-topoisomerase IV interaction and its functional implications in vivo.
Embo J., 32, 2013
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6TED
 | | Structure of complete, activated transcription complex Pol II-DSIF-PAF-SPT6 uncovers allosteric elongation activation by RTF1 | | 分子名称: | DNA (37-MER), DNA-directed RNA polymerase II subunit RPB9, DNA-directed RNA polymerase subunit, ... | | 著者 | Vos, S.M, Farnung, L, Cramer, P. | | 登録日 | 2019-11-11 | | 公開日 | 2020-07-22 | | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | | 主引用文献 | Structure of complete Pol II-DSIF-PAF-SPT6 transcription complex reveals RTF1 allosteric activation.
Nat.Struct.Mol.Biol., 27, 2020
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6GME
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6GMH
 | | Structure of activated transcription complex Pol II-DSIF-PAF-SPT6 | | 分子名称: | CDC73, CTR9,RNA polymerase-associated protein CTR9 homolog,RNA polymerase-associated protein CTR9 homolog, DNA-directed RNA polymerase II subunit RPB9, ... | | 著者 | Vos, S.M, Farnung, L, Boehing, M, Linden, A, Wigge, C, Urlaub, H, Cramer, P. | | 登録日 | 2018-05-26 | | 公開日 | 2018-08-22 | | 最終更新日 | 2019-12-18 | | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | | 主引用文献 | Structure of activated transcription complex Pol II-DSIF-PAF-SPT6.
Nature, 560, 2018
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6GML
 | | Structure of paused transcription complex Pol II-DSIF-NELF | | 分子名称: | DNA-directed RNA polymerase II subunit RPB9, DNA-directed RNA polymerase subunit, DNA-directed RNA polymerase subunit beta, ... | | 著者 | Vos, S.M, Farnung, L, Urlaub, H, Cramer, P. | | 登録日 | 2018-05-27 | | 公開日 | 2018-09-05 | | 最終更新日 | 2024-05-15 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | Structure of paused transcription complex Pol II-DSIF-NELF.
Nature, 560, 2018
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8UIS
 | | Structure of transcription complex Pol II-DSIF-NELF-TFIIS | | 分子名称: | DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit RPB3, DNA-directed RNA polymerase II subunit RPB7, ... | | 著者 | Su, B.G, Vos, S.M. | | 登録日 | 2023-10-10 | | 公開日 | 2024-03-20 | | 最終更新日 | 2024-04-17 | | 実験手法 | ELECTRON MICROSCOPY (3.23 Å) | | 主引用文献 | Distinct negative elongation factor conformations regulate RNA polymerase II promoter-proximal pausing.
Mol.Cell, 84, 2024
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8UHD
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5O9G
 | | Structure of nucleosome-Chd1 complex | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, Chromo domain-containing protein 1, ... | | 著者 | Farnung, L, Vos, S.M, Wigge, C, Cramer, P. | | 登録日 | 2017-06-19 | | 公開日 | 2017-10-11 | | 最終更新日 | 2024-05-15 | | 実験手法 | ELECTRON MICROSCOPY (4.8 Å) | | 主引用文献 | Nucleosome-Chd1 structure and implications for chromatin remodelling.
Nature, 550, 2017
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5L3X
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7UND
 | | Pol II-DSIF-SPT6-PAF1c-TFIIS-nucleosome complex (stalled at +38) | | 分子名称: | DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit RPB3, DNA-directed RNA polymerase II subunit RPB7, ... | | 著者 | Filipovski, M, Vos, S.M, Farnung, L. | | 登録日 | 2022-04-10 | | 公開日 | 2022-10-19 | | 実験手法 | ELECTRON MICROSCOPY (3 Å) | | 主引用文献 | Structural basis of nucleosome retention during transcription elongation.
Science, 376, 2022
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7UNC
 | | Pol II-DSIF-SPT6-PAF1c-TFIIS complex with rewrapped nucleosome | | 分子名称: | DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit RPB3, DNA-directed RNA polymerase II subunit RPB7, ... | | 著者 | Filipovski, M, Vos, S.M, Farnung, L. | | 登録日 | 2022-04-10 | | 公開日 | 2022-10-19 | | 実験手法 | ELECTRON MICROSCOPY (3 Å) | | 主引用文献 | Structural basis of nucleosome retention during transcription elongation.
Science, 376, 2022
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7B0Y
 | | Structure of a transcribing RNA polymerase II-U1 snRNP complex | | 分子名称: | 145-nt RNA, DNA-directed RNA polymerase II subunit D, DNA-directed RNA polymerase II subunit E, ... | | 著者 | Zhang, S, Aibara, S, Vos, S.M, Agafonov, D.E, Luehrmann, R, Cramer, P. | | 登録日 | 2020-11-23 | | 公開日 | 2021-01-13 | | 最終更新日 | 2024-05-01 | | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | | 主引用文献 | Structure of a transcribing RNA polymerase II-U1 snRNP complex.
Science, 371, 2021
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7OKX
 | | Structure of active transcription elongation complex Pol II-DSIF (SPT5-KOW5)-ELL2-EAF1 (composite structure) | | 分子名称: | DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit F, DNA-directed RNA polymerase II subunit RPB1, ... | | 著者 | Chen, Y, Vos, S.M, Dienemann, C, Ninov, M, Urlaub, H, Cramer, P. | | 登録日 | 2021-05-18 | | 公開日 | 2021-07-14 | | 最終更新日 | 2021-09-01 | | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | | 主引用文献 | Allosteric transcription stimulation by RNA polymerase II super elongation complex.
Mol.Cell, 81, 2021
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7OL0
 | | Structure of active transcription elongation complex Pol II-DSIF (SPT5-KOW5) | | 分子名称: | DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit F, DNA-directed RNA polymerase II subunit RPB1, ... | | 著者 | Chen, Y, Vos, S.M, Dienemann, C, Ninov, M, Urlaub, H, Cramer, P. | | 登録日 | 2021-05-18 | | 公開日 | 2021-07-14 | | 最終更新日 | 2021-09-01 | | 実験手法 | ELECTRON MICROSCOPY (3 Å) | | 主引用文献 | Allosteric transcription stimulation by RNA polymerase II super elongation complex.
Mol.Cell, 81, 2021
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7OKY
 | | Structure of active transcription elongation complex Pol II-DSIF-ELL2-EAF1(composite structure) | | 分子名称: | DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit F, DNA-directed RNA polymerase II subunit RPB1, ... | | 著者 | Chen, Y, Vos, S.M, Dienemann, C, Ninov, M, Urlaub, H, Cramer, P. | | 登録日 | 2021-05-18 | | 公開日 | 2021-07-14 | | 最終更新日 | 2021-09-01 | | 実験手法 | ELECTRON MICROSCOPY (4.14 Å) | | 主引用文献 | Allosteric transcription stimulation by RNA polymerase II super elongation complex.
Mol.Cell, 81, 2021
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8A40
 | | Structure of mammalian Pol II-TFIIS elongation complex | | 分子名称: | DNA-directed RNA polymerase II subunit RPB11-a, DNA-directed RNA polymerase II subunit RPB3, DNA-directed RNA polymerase II subunit RPB7, ... | | 著者 | Farnung, L, Ochmann, M, Garg, G, Vos, S.M, Cramer, P. | | 登録日 | 2022-06-09 | | 公開日 | 2023-08-23 | | 実験手法 | ELECTRON MICROSCOPY (3 Å) | | 主引用文献 | Structure of a backtracked hexasomal intermediate of nucleosome transcription.
Mol.Cell, 82, 2022
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6I84
 | | Structure of transcribing RNA polymerase II-nucleosome complex | | 分子名称: | DNA (158-MER), DNA (170-MER), DNA-directed RNA polymerase II subunit RPB1, ... | | 著者 | Farnung, L, Vos, S.M, Cramer, P. | | 登録日 | 2018-11-19 | | 公開日 | 2019-01-02 | | 最終更新日 | 2024-05-15 | | 実験手法 | ELECTRON MICROSCOPY (4.4 Å) | | 主引用文献 | Structure of transcribing RNA polymerase II-nucleosome complex.
Nat Commun, 9, 2018
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8TOF
 | | Rpd3S bound to an H3K36Cme3 modified nucleosome | | 分子名称: | Chromatin modification-related protein EAF3, DNA (176-MER), Histone H2A, ... | | 著者 | Markert, J.W, Vos, S.M, Farnung, L. | | 登録日 | 2023-08-03 | | 公開日 | 2024-01-17 | | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | | 主引用文献 | Structure of the complete Saccharomyces cerevisiae Rpd3S-nucleosome complex.
Nat Commun, 14, 2023
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