8UHA

Structure of paused transcription complex Pol II-DSIF-NELF - tilted

Summary for 8UHA

• Entry DOI: 10.2210/pdb8uha/pdb
• EMDB information: 42267
• Descriptor: Negative elongation factor E, RNA polymerase Rpb4/RPC9 core domain-containing protein, DNA-directed RNA polymerase II subunit E, ... (23 entities in total)
• Functional Keywords: nucleic acids, transcription, rna polymerase ii, nelf, dsif, pausing, transcription-dna-rna complex, transcription/dna/rna
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 21
• Total formula weight: 920837.69

Authors

Vos, S.M.,Su, B.G. (deposition date: 2023-10-08, release date: 2024-03-20)

• Primary citation: Su, B.G.,Vos, S.M.; Distinct negative elongation factor conformations regulate RNA polymerase II promoter-proximal pausing.; Mol.Cell, 2024; PubMed: 38401543; DOI: 10.1016/j.molcel.2024.01.023

Experimental method

ELECTRON MICROSCOPY (3.5 Å)