6GME

Structure of H. sapiens SPT6 tandem SH2 domain

Summary for 6GME

Entry DOI	10.2210/pdb6gme/pdb
Descriptor	SPT6 tandem SH2 domain,Transcription elongation factor SPT6 (2 entities in total)
Functional Keywords	sh2 domain, pol ii interaction, kinase target, transcription factor, transcription
Biological source	Homo sapiens More
Total number of polymer chains	2
Total formula weight	45792.53
Authors	Vos, S.M.,Farnung, L.,Cramer, P. (deposition date: 2018-05-25, release date: 2018-08-22, Last modification date: 2024-01-17)
Primary citation	Vos, S.M.,Farnung, L.,Boehning, M.,Wigge, C.,Linden, A.,Urlaub, H.,Cramer, P. Structure of activated transcription complex Pol II-DSIF-PAF-SPT6. Nature, 560:607-612, 2018 Cited by PubMed: 30135578 DOI: 10.1038/s41586-018-0440-4 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.802 Å)

Structure validation