8UIS

Structure of transcription complex Pol II-DSIF-NELF-TFIIS

Summary for 8UIS

• Entry DOI: 10.2210/pdb8uis/pdb
• EMDB information: 42303
• Descriptor: Non-template DNA, DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerases I, II, and III subunit RPABC2, ... (21 entities in total)
• Functional Keywords: nucleic acids, transcription, rna polymerase ii, nelf, dsif, pausing, transcription-rna-dna complex, transcription/rna/dna
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 19
• Total formula weight: 834090.61

Authors

Su, B.G.,Vos, S.M. (deposition date: 2023-10-10, release date: 2024-03-20, Last modification date: 2024-04-17)

• Primary citation: Su, B.G.,Vos, S.M.; Distinct negative elongation factor conformations regulate RNA polymerase II promoter-proximal pausing.; Mol.Cell, 84:1243-, 2024; PubMed: 38401543; DOI: 10.1016/j.molcel.2024.01.023

Experimental method

ELECTRON MICROSCOPY (3.23 Å)