8A40

Structure of mammalian Pol II-TFIIS elongation complex

Summary for 8A40

• Entry DOI: 10.2210/pdb8a40/pdb
• EMDB information: 15129
• Descriptor: DNA-directed RNA polymerase subunit, DNA-directed RNA polymerases I, II, and III subunit RPABC5, DNA-directed RNA polymerase II subunit RPB11-a, ... (18 entities in total)
• Functional Keywords: chromatin, rna polymerase ii, nucleosome, tfiis, transcription, elongation
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 16
• Total formula weight: 594086.32

Authors

Farnung, L.,Ochmann, M.,Garg, G.,Vos, S.M.,Cramer, P. (deposition date: 2022-06-09, release date: 2023-08-23)

• Primary citation: Farnung, L.,Ochmann, M.,Garg, G.,Vos, S.M.,Cramer, P.; Structure of a backtracked hexasomal intermediate of nucleosome transcription.; Mol.Cell, 82:3126-3134.e7, 2022; PubMed: 35858621; DOI: 10.1016/j.molcel.2022.06.027

Experimental method

ELECTRON MICROSCOPY (3 Å)