8UHG
Structure of paused transcription complex Pol II-DSIF-NELF - poised post-translocated
Summary for 8UHG
Entry DOI | 10.2210/pdb8uhg/pdb |
EMDB information | 42280 |
Descriptor | Negative elongation factor E, DNA-directed RNA polymerase subunit, DNA-directed RNA polymerases I, II, and III subunit RPABC3, ... (22 entities in total) |
Functional Keywords | nucleic acids, transcription, rna polymerase ii, nelf, dsif, pausing, transcription-dna-rna complex, transcription/dna/rna |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 20 |
Total formula weight | 900735.31 |
Authors | |
Primary citation | Su, B.G.,Vos, S.M. Distinct negative elongation factor conformations regulate RNA polymerase II promoter-proximal pausing. Mol.Cell, 84:1243-, 2024 Cited by PubMed: 38401543DOI: 10.1016/j.molcel.2024.01.023 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (2.7 Å) |
Structure validation
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