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PDB: 117 件

6KDF
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BU of 6kdf by Molmil
Crystal structure of the alpha beta heterodimer of human IDH3 in APO form.
分子名称: Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial, Isocitrate dehydrogenase [NAD] subunit beta
著者Sun, P, Ding, J.
登録日2019-07-02
公開日2019-09-25
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (3.05 Å)
主引用文献Molecular basis for the function of the alpha beta heterodimer of human NAD-dependent isocitrate dehydrogenase.
J.Biol.Chem., 294, 2019
6KE3
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BU of 6ke3 by Molmil
Crystal structure of the alpha bata heterodimer of human IDH3 in complex with NADH
分子名称: 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial, ...
著者Sun, P, Ding, J.
登録日2019-07-03
公開日2019-09-25
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (3.307 Å)
主引用文献Molecular basis for the function of the alpha beta heterodimer of human NAD-dependent isocitrate dehydrogenase.
J.Biol.Chem., 294, 2019
6L57
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Crystal structure of the alpha gamma heterodimer of human IDH3 in complex with CIT , Mg and ATP binding at allosteric site.
分子名称: ADENOSINE-5'-TRIPHOSPHATE, CITRIC ACID, Isocitrate dehydrogenase [NAD] subunit alpha, ...
著者Sun, P, Ding, J.
登録日2019-10-22
公開日2020-04-29
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.302 Å)
主引用文献Molecular mechanism of the dual regulatory roles of ATP on the alpha gamma heterodimer of human NAD-dependent isocitrate dehydrogenase.
Sci Rep, 10, 2020
1AA6
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BU of 1aa6 by Molmil
REDUCED FORM OF FORMATE DEHYDROGENASE H FROM E. COLI
分子名称: 2-AMINO-5,6-DIMERCAPTO-7-METHYL-3,7,8A,9-TETRAHYDRO-8-OXA-1,3,9,10-TETRAAZA-ANTHRACEN-4-ONE GUANOSINE DINUCLEOTIDE, FORMATE DEHYDROGENASE H, IRON/SULFUR CLUSTER, ...
著者Sun, P.D, Boyington, J.C.
登録日1997-01-23
公開日1997-08-20
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal structure of formate dehydrogenase H: catalysis involving Mo, molybdopterin, selenocysteine, and an Fe4S4 cluster.
Science, 275, 1997
6KDE
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BU of 6kde by Molmil
Crystal structure of the alpha beta heterodimer of human IDH3 in complex with Ca(2+)
分子名称: CALCIUM ION, Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial, ...
著者Sun, P, Ding, J.
登録日2019-07-02
公開日2019-09-25
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.999 Å)
主引用文献Molecular basis for the function of the alpha beta heterodimer of human NAD-dependent isocitrate dehydrogenase.
J.Biol.Chem., 294, 2019
8DT3
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BU of 8dt3 by Molmil
Cryo-EM structure of spike binding to Fab of neutralizing antibody (locally refined)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain Fab of SW186, Light chain Fab of SW186, ...
著者Sun, P.C, Fang, Y, Bai, X.C, Chen, Z.J.
登録日2022-07-25
公開日2022-08-03
最終更新日2022-11-09
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献An antibody that neutralizes SARS-CoV-1 and SARS-CoV-2 by binding to a conserved spike epitope outside the receptor binding motif.
Sci Immunol, 7, 2022
7CE3
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BU of 7ce3 by Molmil
Crystal structure of human IDH3 holoenzyme in APO form.
分子名称: Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial, Isocitrate dehydrogenase [NAD] subunit beta, ...
著者Sun, P.K, Ding, J.P.
登録日2020-06-21
公開日2021-01-06
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (3.472 Å)
主引用文献Structure and allosteric regulation of human NAD-dependent isocitrate dehydrogenase.
Cell Discov, 6, 2020
1FDI
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BU of 1fdi by Molmil
OXIDIZED FORM OF FORMATE DEHYDROGENASE H FROM E. COLI COMPLEXED WITH THE INHIBITOR NITRITE
分子名称: 2-AMINO-5,6-DIMERCAPTO-7-METHYL-3,7,8A,9-TETRAHYDRO-8-OXA-1,3,9,10-TETRAAZA-ANTHRACEN-4-ONE GUANOSINE DINUCLEOTIDE, FORMATE DEHYDROGENASE H, IRON/SULFUR CLUSTER, ...
著者Sun, P.D, Boyington, J.C.
登録日1997-01-28
公開日1997-08-20
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Crystal structure of formate dehydrogenase H: catalysis involving Mo, molybdopterin, selenocysteine, and an Fe4S4 cluster.
Science, 275, 1997
1FDO
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BU of 1fdo by Molmil
OXIDIZED FORM OF FORMATE DEHYDROGENASE H FROM E. COLI
分子名称: 2-AMINO-5,6-DIMERCAPTO-7-METHYL-3,7,8A,9-TETRAHYDRO-8-OXA-1,3,9,10-TETRAAZA-ANTHRACEN-4-ONE GUANOSINE DINUCLEOTIDE, FORMATE DEHYDROGENASE H, IRON/SULFUR CLUSTER, ...
著者Sun, P.D, Boyington, J.C.
登録日1997-01-27
公開日1997-08-20
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Crystal structure of formate dehydrogenase H: catalysis involving Mo, molybdopterin, selenocysteine, and an Fe4S4 cluster.
Science, 275, 1997
2QWU
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BU of 2qwu by Molmil
Crystal structure of F. tularensis pathogenicity island protein C
分子名称: Intracellular growth locus, subunit C
著者Sun, P, Austin, B.P, Schubot, F.D, Waugh, D.S.
登録日2007-08-10
公開日2007-10-16
最終更新日2021-10-20
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Crystal structure of Francisella tularensis pathogenicity island protein IglC
To be Published
1ZDE
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BU of 1zde by Molmil
1.95 Angstrom Crystal Structure of a dnaE Intein Precursor from Synechocystis Sp. Pcc 6803
分子名称: CALCIUM ION, DNA polymerase III alpha subunit, ZINC ION
著者Sun, P, Ye, S, Ferrandon, S, Evans, T.C, Xu, M.Q, Rao, Z.
登録日2005-04-14
公開日2006-01-24
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Crystal structures of an intein from the split dnaE gene of Synechocystis sp. PCC6803 reveal the catalytic model without the penultimate histidine and the mechanism of zinc ion inhibition of protein splicing
J.Mol.Biol., 353, 2005
1ZD7
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BU of 1zd7 by Molmil
1.7 Angstrom Crystal Structure Of Post-Splicing Form of a dnaE Intein from Synechocystis Sp. Pcc 6803
分子名称: DNA polymerase III alpha subunit, SULFATE ION
著者Sun, P, Ye, S, Ferrandon, S, Evans, T.C, Xu, M.Q, Rao, Z.
登録日2005-04-14
公開日2006-01-24
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Crystal structures of an intein from the split dnaE gene of Synechocystis sp. PCC6803 reveal the catalytic model without the penultimate histidine and the mechanism of zinc ion inhibition of protein splicing
J.Mol.Biol., 353, 2005
6ULN
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BU of 6uln by Molmil
Molecular basis for tumor infiltrating TCR recognition of hotspot KRAS-G12D mutation
分子名称: Beta-2-microglobulin, GLY-ALA-ASP-GLY-VAL-GLY-LYS-SER-ALA, GLYCEROL, ...
著者Sun, P.D, Sim, M.J.W.
登録日2019-10-08
公開日2020-05-27
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.01 Å)
主引用文献High-affinity oligoclonal TCRs define effective adoptive T cell therapy targeting mutant KRAS-G12D.
Proc.Natl.Acad.Sci.USA, 117, 2020
8GS5
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BU of 8gs5 by Molmil
Crystal structure of a constitutively active mutant of human IDH3 holoenzyme in apo form
分子名称: Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial, Isocitrate dehydrogenase [NAD] subunit gamma, ...
著者Sun, P, Chen, X, Ding, J.
登録日2022-09-04
公開日2022-11-30
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (4.486 Å)
主引用文献Structures of a constitutively active mutant of human IDH3 reveal new insights into the mechanisms of allosteric activation and the catalytic reaction.
J.Biol.Chem., 298, 2022
8GRB
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BU of 8grb by Molmil
Crystal structure of a constitutively active mutant of the alpha beta heterodimer of human IDH3
分子名称: Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial, Isoform A of Isocitrate dehydrogenase [NAD] subunit beta
著者Sun, P, Chen, X, Ding, J.
登録日2022-09-01
公開日2022-12-07
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (2.848 Å)
主引用文献Structures of a constitutively active mutant of human IDH3 reveal new insights into the mechanisms of allosteric activation and the catalytic reaction.
J.Biol.Chem., 298, 2022
5ZUG
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BU of 5zug by Molmil
Structure of the bacterial acetate channel SatP
分子名称: Succinate-acetate/proton symporter SatP, nonyl beta-D-glucopyranoside
著者Sun, P.C, Li, J.L, Xiao, Q.J, Guan, Z.Y, Deng, D.
登録日2018-05-07
公開日2018-11-21
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (2.802 Å)
主引用文献Crystal structure of the bacterial acetate transporter SatP reveals that it forms a hexameric channel.
J. Biol. Chem., 293, 2018
6ULR
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BU of 6ulr by Molmil
Molecular basis for tumor infiltrating TCR recognition of hotspot KRAS-G12D mutation
分子名称: Beta-2-microglobulin, GLY-ALA-ASP-GLY-VAL-GLY-LYS-SER-ALA, HLA class I antigen, ...
著者Sun, P.D, Sim, M.J.W.
登録日2019-10-08
公開日2020-05-27
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献High-affinity oligoclonal TCRs define effective adoptive T cell therapy targeting mutant KRAS-G12D.
Proc.Natl.Acad.Sci.USA, 117, 2020
6UON
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BU of 6uon by Molmil
Molecular basis for tumor infiltrating TCR recognition of hotspot KRAS-G12D mutation
分子名称: Beta-2-microglobulin, GLY-ALA-ASP-GLY-VAL-GLY-LYS-SER-ALA-LEU, HLA class I antigen, ...
著者Sun, P.D, Sim, M.J.W.
登録日2019-10-15
公開日2020-05-27
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献High-affinity oligoclonal TCRs define effective adoptive T cell therapy targeting mutant KRAS-G12D.
Proc.Natl.Acad.Sci.USA, 117, 2020
8GRH
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BU of 8grh by Molmil
Crystal structure of a constitutively active mutant of the alpha gamma heterodimer of human IDH3 in complex with CIT
分子名称: CITRIC ACID, Human IDH3 alpha subunit, Isocitrate dehydrogenase [NAD] subunit gamma, ...
著者Sun, P, Chen, X, Ding, J.
登録日2022-09-01
公開日2022-11-30
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.506 Å)
主引用文献Structures of a constitutively active mutant of human IDH3 reveal new insights into the mechanisms of allosteric activation and the catalytic reaction.
J.Biol.Chem., 298, 2022
6ULI
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BU of 6uli by Molmil
Molecular basis for tumor infiltrating TCR recognition of hotspot KRAS-G12D mutation
分子名称: Beta-2-microglobulin, GLY-ALA-ASP-GLY-VAL-GLY-LYS-SER-ALA, HLA class I antigen
著者Sun, P.D, Sim, M.J.W.
登録日2019-10-08
公開日2020-05-27
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.88 Å)
主引用文献High-affinity oligoclonal TCRs define effective adoptive T cell therapy targeting mutant KRAS-G12D.
Proc.Natl.Acad.Sci.USA, 117, 2020
6ULK
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BU of 6ulk by Molmil
Molecular basis for tumor infiltrating TCR recognition of hotspot KRAS-G12D mutation
分子名称: Beta-2-microglobulin, GLY-ALA-ASP-GLY-VAL-GLY-LYS-SER-ALA-LEU, HLA class I antigen
著者Sun, P.D, Sim, M.J.W.
登録日2019-10-08
公開日2020-05-27
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献High-affinity oligoclonal TCRs define effective adoptive T cell therapy targeting mutant KRAS-G12D.
Proc.Natl.Acad.Sci.USA, 117, 2020
8GRG
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BU of 8grg by Molmil
Crystal structure of a constitutively active mutant of the alpha gamma heterodimer of human IDH3
分子名称: Human IDH3 alpha subunit, Isocitrate dehydrogenase [NAD] subunit gamma, mitochondrial
著者Sun, P, Chen, X, Ding, J.
登録日2022-09-01
公開日2022-11-30
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.699 Å)
主引用文献Structures of a constitutively active mutant of human IDH3 reveal new insights into the mechanisms of allosteric activation and the catalytic reaction.
J.Biol.Chem., 298, 2022
8GRU
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BU of 8gru by Molmil
Crystal structure of a constitutively active mutant of the alpha beta heterodimer of human IDH3 in complex with ICT, NAD and Ca
分子名称: CALCIUM ION, Human IDH3 alpha subunit, ISOCITRIC ACID, ...
著者Sun, P, Chen, X, Ding, J.
登録日2022-09-02
公開日2022-11-30
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.847 Å)
主引用文献Structures of a constitutively active mutant of human IDH3 reveal new insights into the mechanisms of allosteric activation and the catalytic reaction.
J.Biol.Chem., 298, 2022
6KDY
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BU of 6kdy by Molmil
Crystal structure of the alpha bata heterodimer of human IDH3 in complex with NAD.
分子名称: 1-DEOXY-1-THIO-HEPTAETHYLENE GLYCOL, HEXAETHYLENE GLYCOL, Isocitrate dehydrogenase [NAD] subunit alpha, ...
著者Sun, P, Ding, J.
登録日2019-07-03
公開日2019-09-25
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (3.02 Å)
主引用文献Molecular basis for the function of the alpha beta heterodimer of human NAD-dependent isocitrate dehydrogenase.
J.Biol.Chem., 294, 2019
2DL2
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KILLER IMMUNOGLOBULIN RECEPTOR 2DL2
分子名称: PROTEIN (MHC CLASS I NK CELL RECEPTOR PRECURSOR (P58 NATURAL KILLER CELL RECEPTOR CLONE CL-43))
著者Sun, P, Snyder, G.
登録日1999-03-08
公開日1999-03-30
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Crystal structure of the HLA-Cw3 allotype-specific killer cell inhibitory receptor KIR2DL2
Proc.Natl.Acad.Sci.USA, 96, 1999

224004

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