8DT3

Cryo-EM structure of spike binding to Fab of neutralizing antibody (locally refined)

Summary for 8DT3

Entry DOI	10.2210/pdb8dt3/pdb
EMDB information	27690
Descriptor	Spike glycoprotein, Heavy chain Fab of SW186, Light chain Fab of SW186, ... (4 entities in total)
Functional Keywords	sars-cov2, antibody, neutralizing, viral protein-immune system complex, viral protein/immune system
Biological source	Severe acute respiratory syndrome coronavirus 2 More
Total number of polymer chains	3
Total formula weight	192781.59
Authors	Sun, P.C.,Fang, Y.,Bai, X.C.,Chen, Z.J. (deposition date: 2022-07-25, release date: 2022-08-03, Last modification date: 2022-11-09)
Primary citation	Fang, Y.,Sun, P.,Xie, X.,Du, M.,Du, F.,Ye, J.,Kalveram, B.K.,Plante, J.A.,Plante, K.S.,Li, B.,Bai, X.C.,Shi, P.Y.,Chen, Z.J. An antibody that neutralizes SARS-CoV-1 and SARS-CoV-2 by binding to a conserved spike epitope outside the receptor binding motif. Sci Immunol, 7:eabp9962-eabp9962, 2022 Cited by PubMed: 35926067 DOI: 10.1126/sciimmunol.abp9962 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.3 Å)

Structure validation