7UY5
| Tetrahymena telomerase with CST | Descriptor: | Telomerase La-related protein p65, Telomerase RNA, Telomerase associated protein p50, ... | Authors: | He, Y, Song, H, Chan, H, Wang, Y, Liu, B, Susac, L, Zhou, Z.H, Feigon, J. | Deposit date: | 2022-05-06 | Release date: | 2022-07-13 | Last modified: | 2024-02-14 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Structure of Tetrahymena telomerase-bound CST with polymerase alpha-primase. Nature, 608, 2022
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1OIL
| STRUCTURE OF LIPASE | Descriptor: | CALCIUM ION, LIPASE | Authors: | Kim, K.K, Song, H.K, Shin, D.H, Suh, S.W. | Deposit date: | 1996-12-06 | Release date: | 1997-05-15 | Last modified: | 2018-04-18 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | The crystal structure of a triacylglycerol lipase from Pseudomonas cepacia reveals a highly open conformation in the absence of a bound inhibitor. Structure, 5, 1997
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5N0O
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7TRF
| Human telomerase catalytic core RNP with H2A/H2B | Descriptor: | Histone H2A, Histone H2B type 1-C/E/F/G/I, Telomerase RNA, ... | Authors: | Liu, B, He, Y, Wang, Y, Song, H, Zhou, Z.H, Feigon, J. | Deposit date: | 2022-01-28 | Release date: | 2022-04-20 | Last modified: | 2024-02-21 | Method: | ELECTRON MICROSCOPY (3.7 Å) | Cite: | Structure of active human telomerase with telomere shelterin protein TPP1. Nature, 604, 2022
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5N0P
| Crystal structure of OphA-DeltaC18 in complex with SAH | Descriptor: | 1,2-ETHANEDIOL, S-ADENOSYL-L-HOMOCYSTEINE, peptide N-methyltranferase | Authors: | Naismith, J.H, Song, H. | Deposit date: | 2017-02-03 | Release date: | 2018-02-14 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.16 Å) | Cite: | A molecular mechanism for the enzymatic methylation of nitrogen atoms within peptide bonds. Sci Adv, 4, 2018
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7UY7
| Tetrahymena CST with Polymerase alpha-Primase | Descriptor: | DNA polymerase, Telomerase associated protein p50, Telomerase-associated protein of 19 kDa, ... | Authors: | He, Y, Song, H, Chan, H, Wang, Y, Liu, B, Susac, L, Zhou, Z.H, Feigon, J. | Deposit date: | 2022-05-06 | Release date: | 2022-07-13 | Last modified: | 2024-02-14 | Method: | ELECTRON MICROSCOPY (4.2 Å) | Cite: | Structure of Tetrahymena telomerase-bound CST with polymerase alpha-primase. Nature, 608, 2022
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7UY8
| Tetrahymena Polymerase alpha-Primase | Descriptor: | DNA polymerase, DNA polymerase alpha subunit B, DNA primase, ... | Authors: | He, Y, Song, H, Chan, H, Wang, Y, Liu, B, Susac, L, Zhou, Z.H, Feigon, J. | Deposit date: | 2022-05-06 | Release date: | 2022-07-13 | Last modified: | 2024-02-14 | Method: | ELECTRON MICROSCOPY (4.5 Å) | Cite: | Structure of Tetrahymena telomerase-bound CST with polymerase alpha-primase. Nature, 608, 2022
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1QZY
| Human Methionine Aminopeptidase in complex with bengamide inhibitor LAF153 and cobalt | Descriptor: | (E)-(2R,3R,4S,5R)-3,4,5-TRIHYDROXY-2-METHOXY-8,8-DIMETHYL-NON-6-ENOIC ACID ((3S,6R)-6-HYDROXY-2-OXO-AZEPAN-3-YL)-AMIDE, COBALT (II) ION, Methionine aminopeptidase 2, ... | Authors: | Eck, M.J, Song, H.K, Morollo, A. | Deposit date: | 2003-09-18 | Release date: | 2003-11-25 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Proteomics-based target identification: bengamides as a new class of methionine aminopeptidase inhibitors. J.Biol.Chem., 278, 2003
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6LG2
| VanR bound to Vanillate | Descriptor: | 4-HYDROXY-3-METHOXYBENZOATE, Predicted transcriptional regulators | Authors: | He, Y, Bharath, S.R, Song, H. | Deposit date: | 2019-12-04 | Release date: | 2020-02-12 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Developing a highly efficient hydroxytyrosol whole-cell catalyst by de-bottlenecking rate-limiting steps. Nat Commun, 11, 2020
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6KY8
| Crystal structure of ASFV dUTPase | Descriptor: | E165R | Authors: | Li, C, Chai, Y, Song, H, Qi, J, Sun, Y, Gao, G.F. | Deposit date: | 2019-09-17 | Release date: | 2019-11-13 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.301 Å) | Cite: | Crystal Structure of African Swine Fever Virus dUTPase Reveals a Potential Drug Target. Mbio, 10, 2019
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5N0Q
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7TRD
| Human telomerase catalytic core structure at 3.3 Angstrom | Descriptor: | Telomerase RNA, partial sequence, Telomerase reverse transcriptase, ... | Authors: | Liu, B, He, Y, Wang, Y, Song, H, Zhou, Z.H, Feigon, J. | Deposit date: | 2022-01-28 | Release date: | 2022-04-20 | Last modified: | 2024-02-21 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Structure of active human telomerase with telomere shelterin protein TPP1. Nature, 604, 2022
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7TRE
| Human telomerase catalytic core with shelterin protein TPP1 | Descriptor: | Adrenocortical dysplasia protein homolog, Telomerase RNA, partial sequence, ... | Authors: | Liu, B, He, Y, Wang, Y, Song, H, Zhou, Z.H, Feigon, J. | Deposit date: | 2022-01-28 | Release date: | 2022-04-20 | Last modified: | 2024-02-21 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Structure of active human telomerase with telomere shelterin protein TPP1. Nature, 604, 2022
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6SJ4
| Amidohydrolase, AHS with substrate analog | Descriptor: | 1,2-ETHANEDIOL, 3-(3-hydroxyphenyl)carbonyloxybenzoic acid, Amidohydrolase, ... | Authors: | Naismith, J.H, Song, H. | Deposit date: | 2019-08-12 | Release date: | 2020-01-15 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.81 Å) | Cite: | The Biosynthesis of the Benzoxazole in Nataxazole Proceeds via an Unstable Ester and has Synthetic Utility. Angew.Chem.Int.Ed.Engl., 59, 2020
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1NTV
| Crystal Structure of the Disabled-1 (Dab1) PTB domain-ApoER2 peptide complex | Descriptor: | Apolipoprotein E Receptor-2 peptide, Disabled homolog 1, PHOSPHATE ION | Authors: | Stolt, P.C, Jeon, H, Song, H.K, Herz, J, Eck, M.J, Blacklow, S.C. | Deposit date: | 2003-01-30 | Release date: | 2003-04-15 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Origins of Peptide Selectivity and Phosphoinositide Binding Revealed by Structures of Disabled-1 PTB Domain Complexes Structure, 11, 2003
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1NU2
| Crystal structure of the murine Disabled-1 (Dab1) PTB domain-ApoER2 peptide-PI-4,5P2 ternary complex | Descriptor: | D-MYO-INOSITOL-1,4,5-TRIPHOSPHATE, Disabled homolog 1, peptide derived from murine Apolipoprotein E Receptor-2 | Authors: | Stolt, P.C, Jeon, H, Song, H.K, Herz, J, Eck, M.J, Blacklow, S.C. | Deposit date: | 2003-01-30 | Release date: | 2003-04-15 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Origins of Peptide Selectivity and Phosphoinositide Binding Revealed by Structures of Disabled-1 PTB Domain Complexes Structure, 11, 2003
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1C78
| STAPHYLOKINASE (SAK) DIMER | Descriptor: | STAPHYLOKINASE | Authors: | Rao, Z, Jiang, F, Liu, Y, Zhang, X, Chen, Y, Bartlam, M, Song, H, Ding, Y. | Deposit date: | 2000-02-01 | Release date: | 2000-08-01 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Crystal structure of a staphylokinase: variant a model for reduced antigenicity. Eur.J.Biochem., 269, 2002
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1C77
| STAPHYLOKINASE (SAK) DIMER | Descriptor: | STAPHYLOKINASE | Authors: | Rao, Z, Jiang, F, Liu, Y, Zhang, X, Chen, Y, Bartlam, M, Song, H, Ding, Y. | Deposit date: | 2000-02-01 | Release date: | 2000-08-01 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Crystal structure of a staphylokinase: variant a model for reduced antigenicity. Eur.J.Biochem., 269, 2002
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1C79
| STAPHYLOKINASE (SAK) DIMER | Descriptor: | STAPHYLOKINASE | Authors: | Rao, Z, Jiang, F, Liu, Y, Zhang, X, Chen, Y, Bartlam, M, Song, H, Ding, Y. | Deposit date: | 2000-02-01 | Release date: | 2000-08-01 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Crystal structure of a staphylokinase: variant a model for reduced antigenicity. Eur.J.Biochem., 269, 2002
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6LXI
| Crystal structure of Z2B3 Fab in complex with influenza virus neuraminidase from A/Brevig Mission/1/1918 (H1N1) | Descriptor: | CALCIUM ION, Heavy chain of Z2B3 Fab, Light chain of Z2B3 Fab, ... | Authors: | Jiang, H, Peng, W, Qi, J, Chai, Y, Song, H, Shi, Y, Gao, G.F, Wu, Y. | Deposit date: | 2020-02-11 | Release date: | 2020-12-02 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structure-Based Modification of an Anti-neuraminidase Human Antibody Restores Protection Efficacy against the Drifted Influenza Virus. Mbio, 11, 2020
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6LXJ
| Crystal structure of human Z2B3 Fab in complex with influenza virus neuraminidase from A/Anhui/1/2013 (H7N9) | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Heavy chain of Z2B3 Fab, ... | Authors: | Jiang, H, Peng, W, Qi, J, Chai, Y, Song, H, Shi, Y, Gao, G.F, Wu, Y. | Deposit date: | 2020-02-11 | Release date: | 2020-12-02 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.903 Å) | Cite: | Structure-Based Modification of an Anti-neuraminidase Human Antibody Restores Protection Efficacy against the Drifted Influenza Virus. Mbio, 11, 2020
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4XTB
| Crystal structure of the N-terminal domain of the human mitochondrial calcium uniporter | Descriptor: | Calcium uniporter protein, mitochondrial, TETRAETHYLENE GLYCOL | Authors: | Lee, Y, Min, C.K, Kim, T.G, Song, H.K, Lim, Y, Kim, D, Shin, K, Kang, M, Kang, J.Y, Youn, H.-S, Lee, J.-G, An, J.Y, Park, K.R, Lim, J.J, Kim, J.H, Kim, J.H, Park, Z.Y, Kim, Y.-S, Wang, J, Kim, D.H, Eom, S.H. | Deposit date: | 2015-01-23 | Release date: | 2015-09-16 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Structure and function of the N-terminal domain of the human mitochondrial calcium uniporter. Embo Rep., 16, 2015
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5JXE
| Human PD-1 ectodomain complexed with Pembrolizumab Fab | Descriptor: | Pembrolizumab Fab heavy chain, Pembrolizumab Fab light chain, Programmed cell death protein 1 | Authors: | Na, Z, Bharath, S.R, Song, H. | Deposit date: | 2016-05-13 | Release date: | 2016-08-10 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Structural basis for blocking PD-1-mediated immune suppression by therapeutic antibody pembrolizumab. Cell Res., 27, 2017
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2AFF
| The solution structure of the Ki67FHA/hNIFK(226-269)3P complex | Descriptor: | Antigen KI-67, MKI67 FHA domain interacting nucleolar phosphoprotein | Authors: | Byeon, I.-J.L, Li, H, Song, H, Gronenborn, A.M, Tsai, M.D. | Deposit date: | 2005-07-25 | Release date: | 2005-10-25 | Last modified: | 2022-03-09 | Method: | SOLUTION NMR | Cite: | Sequential phosphorylation and multisite interactions characterize specific target recognition by the FHA domain of Ki67. Nat.Struct.Mol.Biol., 12, 2005
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1JXV
| Crystal Structure of Human Nucleoside Diphosphate Kinase A | Descriptor: | Nucleoside Diphosphate Kinase A | Authors: | Min, K, Song, H.K, Chang, C, Kim, S.Y, Lee, K.J, Suh, S.W. | Deposit date: | 2001-09-10 | Release date: | 2002-04-10 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Crystal structure of human nucleoside diphosphate kinase A, a metastasis suppressor. Proteins, 46, 2002
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