7TRE
Human telomerase catalytic core with shelterin protein TPP1
Summary for 7TRE
Entry DOI | 10.2210/pdb7tre/pdb |
EMDB information | 26087 |
Descriptor | Telomerase RNA, partial sequence, Telomerase reverse transcriptase, Telomeric repeat substrate, ... (4 entities in total) |
Functional Keywords | dna, rna, replication |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 4 |
Total formula weight | 299376.49 |
Authors | Liu, B.,He, Y.,Wang, Y.,Song, H.,Zhou, Z.H.,Feigon, J. (deposition date: 2022-01-28, release date: 2022-04-20, Last modification date: 2024-02-21) |
Primary citation | Liu, B.,He, Y.,Wang, Y.,Song, H.,Zhou, Z.H.,Feigon, J. Structure of active human telomerase with telomere shelterin protein TPP1. Nature, 604:578-583, 2022 Cited by PubMed: 35418675DOI: 10.1038/s41586-022-04582-8 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.5 Å) |
Structure validation
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