6LXJ

Crystal structure of human Z2B3 Fab in complex with influenza virus neuraminidase from A/Anhui/1/2013 (H7N9)

Summary for 6LXJ

• Entry DOI: 10.2210/pdb6lxj/pdb
• Descriptor: Neuraminidase, Heavy chain of Z2B3 Fab, Light chain of Z2B3 Fab, ... (8 entities in total)
• Functional Keywords: antibody, antigen, complex, immune system, hydrolase-immune system complex, hydrolase/immune system
• Biological source: Influenza A virus (A/Anhui/1-BALF_RG44/2013(H7N9)); More
• Total number of polymer chains: 12
• Total formula weight: 376370.17

Authors

Jiang, H.,Peng, W.,Qi, J.,Chai, Y.,Song, H.,Shi, Y.,Gao, G.F.,Wu, Y. (deposition date: 2020-02-11, release date: 2020-12-02, Last modification date: 2023-11-29)

• Primary citation: Jiang, H.,Peng, W.,Qi, J.,Chai, Y.,Song, H.,Bi, Y.,Rijal, P.,Wang, H.,Oladejo, B.O.,Liu, J.,Shi, Y.,Gao, G.F.,Townsend, A.R.,Wu, Y.; Structure-Based Modification of an Anti-neuraminidase Human Antibody Restores Protection Efficacy against the Drifted Influenza Virus.; Mbio, 11:-, 2020; PubMed: 33024040; DOI: 10.1128/mBio.02315-20

Experimental method

X-RAY DIFFRACTION (2.903 Å)