6LXJ

Crystal structure of human Z2B3 Fab in complex with influenza virus neuraminidase from A/Anhui/1/2013 (H7N9)

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D (A, B, C, D)	Neuraminidase	polymer	388	43553.5	4	UniProt (A0A024E1X5) Pfam (PF00064)	Influenza A virus (A/Anhui/1-BALF_RG44/2013(H7N9))
2	E, G, I, K (H, E, J, M)	Heavy chain of Z2B3 Fab	polymer	237	25133.1	4		Homo sapiens
3	F, H, J, L (L, F, K, N)	Light chain of Z2B3 Fab	polymer	216	22796.0	4		Homo sapiens
4	M (G)	alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		910.8	1	In PDB GlyTouCan (G22768VO)
5	N, P, R, T (I, P, R, T)	alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		1559.4	4	In PDB GlyTouCan (G68668TB)
6	O, Q, S (O, Q, S)	alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		748.7	3	In PDB GlyTouCan (G22573RC)
7	AA, U, W, Y (D, A, B, C)	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	4	Chemie (NAG)
8	BA, V, X, Z (D, A, B, C)	CALCIUM ION	non-polymer		40.1	4	Chemie (CA)

Contents of the asymmetric unit

Polymers	Number of chains	12
	Total formula weight	365930.6
Branched	Number of molecules	8
	Total formula weight	9394.4
Non-Polymers*	Number of molecules	8
	Total formula weight	1045.1
All*	Total formula weight	376370.2

*Water molecules are not included.