7TRD

Human telomerase catalytic core structure at 3.3 Angstrom

Summary for 7TRD

Entry DOI	10.2210/pdb7trd/pdb
EMDB information	26086
Descriptor	Telomerase RNA, partial sequence, Telomerase reverse transcriptase, Telomeric repeat substrate (3 entities in total)
Functional Keywords	dna, rna, replication
Biological source	Homo sapiens (human) More
Total number of polymer chains	3
Total formula weight	281703.86
Authors	Liu, B.,He, Y.,Wang, Y.,Song, H.,Zhou, Z.H.,Feigon, J. (deposition date: 2022-01-28, release date: 2022-04-20, Last modification date: 2024-02-21)
Primary citation	Liu, B.,He, Y.,Wang, Y.,Song, H.,Zhou, Z.H.,Feigon, J. Structure of active human telomerase with telomere shelterin protein TPP1. Nature, 604:578-583, 2022 Cited by PubMed: 35418675 DOI: 10.1038/s41586-022-04582-8 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.3 Å)

Structure validation