1NU2

Crystal structure of the murine Disabled-1 (Dab1) PTB domain-ApoER2 peptide-PI-4,5P2 ternary complex

Summary for 1NU2

• Entry DOI: 10.2210/pdb1nu2/pdb
• Related: 1NTV
• Descriptor: Disabled homolog 1, peptide derived from murine Apolipoprotein E Receptor-2, D-MYO-INOSITOL-1,4,5-TRIPHOSPHATE, ... (4 entities in total)
• Functional Keywords: beta-sandwich, signaling protein
• Biological source: Mus musculus (house mouse); More
• Total number of polymer chains: 2
• Total formula weight: 18760.24

Authors

Stolt, P.C.,Jeon, H.,Song, H.K.,Herz, J.,Eck, M.J.,Blacklow, S.C. (deposition date: 2003-01-30, release date: 2003-04-15, Last modification date: 2024-03-13)

• Primary citation: Stolt, P.C.,Jeon, H.,Song, H.K.,Herz, J.,Eck, M.J.,Blacklow, S.C.; Origins of Peptide Selectivity and Phosphoinositide Binding Revealed by Structures of Disabled-1 PTB Domain Complexes; Structure, 11:569-579, 2003; PubMed: 12737822; DOI: 10.1016/S0969-2126(03)00068-6

Experimental method

X-RAY DIFFRACTION (1.9 Å)