8D3C
 
 | | VWF tubule derived from monomeric D1-A1 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, von Willebrand factor | | 著者 | Anderson, J.R, Li, J, Springer, T.A, Brown, A. | | 登録日 | 2022-06-01 | | 公開日 | 2022-07-06 | | 最終更新日 | 2022-10-05 | | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | | 主引用文献 | Structures of VWF tubules before and after concatemerization reveal a mechanism of disulfide bond exchange.
Blood, 140, 2022
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8D3D
 | | VWF tubule derived from dimeric D1-A1 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, von Willebrand factor | | 著者 | Anderson, J.R, Li, J, Springer, T.A, Brown, A. | | 登録日 | 2022-06-01 | | 公開日 | 2022-07-06 | | 最終更新日 | 2022-10-05 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | Structures of VWF tubules before and after concatemerization reveal a mechanism of disulfide bond exchange.
Blood, 140, 2022
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7UQ2
 | | Vs.4 from T4 phage in complex with cGAMP | | 分子名称: | 2-amino-9-[(2R,3R,3aS,5R,7aR,9R,10R,10aS,12R,14aR)-9-(6-amino-9H-purin-9-yl)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecin-2-yl]-1,9-dihydro-6H-purin-6-one, CALCIUM ION, Vs.4 | | 著者 | Jenson, J.M, Chen, Z.J. | | 登録日 | 2022-04-18 | | 公開日 | 2023-02-08 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Ubiquitin-like conjugation by bacterial cGAS enhances anti-phage defence.
Nature, 616, 2023
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5EXH
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6W4W
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6W9G
 | | Crystal Structure of the Fab fragment of humanized 5c8 antibody containing the fluorescent non-canonical amino acid L-(7-hydroxycoumarin-4-yl)ethylglycine in complex with CD40L at pH 6.8 | | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 2-{2-[2-2-(METHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, 5c8* Fab (heavy chain), ... | | 著者 | Henderson, J.N, Simmons, C.R, Mills, J.H. | | 登録日 | 2020-03-23 | | 公開日 | 2020-12-23 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (1.82 Å) | | 主引用文献 | Structural Insights into How Protein Environments Tune the Spectroscopic Properties of a Noncanonical Amino Acid Fluorophore.
Biochemistry, 59, 2020
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6W5A
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7URX
 | | SJ25C1 Fab in complex with soluble CD19 | | 分子名称: | B-lymphocyte antigen CD19, SJ25C1 Fab heavy chain, SJ25C1 Fab light chain | | 著者 | Meyerson, J, He, C. | | 登録日 | 2022-04-22 | | 公開日 | 2023-02-15 | | 最終更新日 | 2023-03-15 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | CD19 CAR antigen engagement mechanisms and affinity tuning.
Sci Immunol, 8, 2023
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7URV
 | | FMC63 scFv in complex with soluble CD19 | | 分子名称: | B-lymphocyte antigen CD19, FMC63 single-chain variable fragment | | 著者 | Meyerson, J, He, C. | | 登録日 | 2022-04-22 | | 公開日 | 2023-02-15 | | 最終更新日 | 2023-03-15 | | 実験手法 | ELECTRON MICROSCOPY (3.05 Å) | | 主引用文献 | CD19 CAR antigen engagement mechanisms and affinity tuning.
Sci Immunol, 8, 2023
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3LOB
 | | Crystal Structure of Flock House Virus calcium mutant | | 分子名称: | Coat protein beta, Coat protein gamma, RNA (5'-R(*UP*UP*U*AP*UP*CP*UP*(P))-3'), ... | | 著者 | Johnson, J.E, Banerjee, M, Speir, J.A, Huang, R. | | 登録日 | 2010-02-03 | | 公開日 | 2010-04-21 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (3.6 Å) | | 主引用文献 | Structure and function of a genetically engineered mimic of a nonenveloped virus entry intermediate.
J.Virol., 84, 2010
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6TZK
 | | Bacterial cellulose synthase outermembrane channel BcsC with terminal TPR repeat | | 分子名称: | (HYDROXYETHYLOXY)TRI(ETHYLOXY)OCTANE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, 3,6,9,12,15,18,21,24-OCTAOXAHEXACOSAN-1-OL, ... | | 著者 | Acheson, J.F, Derewenda, Z, Zimmer, J. | | 登録日 | 2019-08-12 | | 公開日 | 2019-10-23 | | 最終更新日 | 2023-02-15 | | 実験手法 | X-RAY DIFFRACTION (1.852 Å) | | 主引用文献 | Architecture of the Cellulose Synthase Outer Membrane Channel and Its Association with the Periplasmic TPR Domain.
Structure, 27, 2019
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8T5X
 | | Probing the dissociation pathway of a kinetically labile transthyretin mutant (A25T) | | 分子名称: | Transthyretin | | 著者 | Ferguson, J.A, Sun, X, Leach, B.I, Stanfield, R.L, Dyson, H.J, Wright, P.E. | | 登録日 | 2023-06-14 | | 公開日 | 2023-08-02 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (1.63 Å) | | 主引用文献 | Probing the Dissociation Pathway of a Kinetically Labile Transthyretin Mutant.
J.Am.Chem.Soc., 146, 2024
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6WGX
 | | Cocrystal of BRD4(D1) with a selective inhibitor | | 分子名称: | 1,2-ETHANEDIOL, 4-(1-{1-[2-(dimethylamino)ethyl]piperidin-4-yl}-4-[4-(trifluoromethyl)phenyl]-1H-imidazol-5-yl)-N-(3,5-dimethylphenyl)pyrimidin-2-amine, Bromodomain-containing protein 4 | | 著者 | Johnson, J.A, Cui, H, Shi, K, Aihara, H, Pomerantz, W.C.K. | | 登録日 | 2020-04-06 | | 公開日 | 2020-10-07 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (1.53 Å) | | 主引用文献 | Selective N-Terminal BET Bromodomain Inhibitors by Targeting Non-Conserved Residues and Structured Water Displacement*.
Angew.Chem.Int.Ed.Engl., 60, 2021
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8AF2
 | | Human Sterol Carrier Protein with unnatural amino acid 2,2'-bipyridine alanine incorporated at position 111 | | 分子名称: | COPPER (II) ION, Enoyl-CoA hydratase 2, FRAGMENT OF TRITON X-100, ... | | 著者 | Richardson, J.M, Klemencic, E, Jarvis, A.G. | | 登録日 | 2022-07-15 | | 公開日 | 2023-08-16 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.51 Å) | | 主引用文献 | Using BpyAla to generate copper artificial metalloenzymes: a catalytic and structural study.
Catalysis Science And Technology, 14, 2024
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5HDA
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5FRG
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6MBD
 | | Human Mcl-1 in complex with the designed peptide dM1 | | 分子名称: | Induced myeloid leukemia cell differentiation protein Mcl-1, ZINC ION, dM1 | | 著者 | Jenson, J.M, Keating, A.E. | | 登録日 | 2018-08-29 | | 公開日 | 2019-03-06 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | Tertiary Structural Motif Sequence Statistics Enable Facile Prediction and Design of Peptides that Bind Anti-apoptotic Bfl-1 and Mcl-1.
Structure, 27, 2019
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8GET
 | | R. hominis 2 beta-glucuronidase bound to norquetiapine-glucuronide | | 分子名称: | 11-(4-beta-D-glucopyranuronosylpiperazin-1-yl)dibenzo[b,f][1,4]thiazepine, FLAVIN MONONUCLEOTIDE, GLYCEROL, ... | | 著者 | Simpson, J.B, Redinbo, M.R. | | 登録日 | 2023-03-07 | | 公開日 | 2024-03-20 | | 最終更新日 | 2024-06-26 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Gut microbial beta-glucuronidases influence endobiotic homeostasis and are modulated by diverse therapeutics.
Cell Host Microbe, 32, 2024
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6MBE
 | | Human Mcl-1 in complex with the designed peptide dM7 | | 分子名称: | CHLORIDE ION, Induced myeloid leukemia cell differentiation protein Mcl-1, dM7 | | 著者 | Jenson, J.M, Keating, A.E. | | 登録日 | 2018-08-29 | | 公開日 | 2019-03-06 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | | 主引用文献 | Tertiary Structural Motif Sequence Statistics Enable Facile Prediction and Design of Peptides that Bind Anti-apoptotic Bfl-1 and Mcl-1.
Structure, 27, 2019
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6MBC
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8GEO
 | | E. eligens beta-glucuronidase bound to 3-OH-desloratidine-glucuronide | | 分子名称: | 8-chloro-11-(1-beta-D-glucopyranuronosylpiperidin-4-ylidene)-3-hydroxy-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridine, Beta-glucuronidase, GLYCEROL | | 著者 | Simpson, J.B, Redinbo, M.R. | | 登録日 | 2023-03-07 | | 公開日 | 2024-03-20 | | 最終更新日 | 2024-06-26 | | 実験手法 | X-RAY DIFFRACTION (2.89 Å) | | 主引用文献 | Gut microbial beta-glucuronidases influence endobiotic homeostasis and are modulated by diverse therapeutics.
Cell Host Microbe, 32, 2024
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8GER
 | | E. eligens beta-glucuronidase bound to norquetiapine-glucuronide | | 分子名称: | 11-(4-beta-D-glucopyranuronosylpiperazin-1-yl)dibenzo[b,f][1,4]thiazepine, Beta-glucuronidase | | 著者 | Simpson, J.B, Lietzan, A.D, Redinbo, M.R. | | 登録日 | 2023-03-07 | | 公開日 | 2024-03-20 | | 最終更新日 | 2024-06-26 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Gut microbial beta-glucuronidases influence endobiotic homeostasis and are modulated by diverse therapeutics.
Cell Host Microbe, 32, 2024
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6MBB
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4BIQ
 | | Homology model of coxsackievirus A7 (CAV7) empty capsid proteins. | | 分子名称: | VP1, VP2, VP3 | | 著者 | Seitsonen, J.J.T, Shakeel, S, Susi, P, Pandurangan, A.P, Sinkovits, R.S, Hyvonen, H, Laurinmaki, P, Yla-Pelto, J, Topf, M, Hyypia, T, Butcher, S.J. | | 登録日 | 2013-04-12 | | 公開日 | 2013-10-02 | | 最終更新日 | 2024-05-08 | | 実験手法 | ELECTRON MICROSCOPY (6.09 Å) | | 主引用文献 | Combined Approaches to Flexible Fitting and Assessment in Virus Capsids Undergoing Conformational Change.
J.Struct.Biol., 185, 2014
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3C99
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