7UQ2

Vs.4 from T4 phage in complex with cGAMP

Summary for 7UQ2

Entry DOI	10.2210/pdb7uq2/pdb
Descriptor	Vs.4, 2-amino-9-[(2R,3R,3aS,5R,7aR,9R,10R,10aS,12R,14aR)-9-(6-amino-9H-purin-9-yl)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecin-2-yl]-1,9-dihydro-6H-purin-6-one, CALCIUM ION, ... (4 entities in total)
Functional Keywords	binds 3', 3'-cgamp, viral protein
Biological source	Tequatrovirus
Total number of polymer chains	6
Total formula weight	64047.58
Authors	Jenson, J.M.,Chen, Z.J. (deposition date: 2022-04-18, release date: 2023-02-08, Last modification date: 2024-04-03)
Primary citation	Jenson, J.M.,Li, T.,Du, F.,Ea, C.K.,Chen, Z.J. Ubiquitin-like conjugation by bacterial cGAS enhances anti-phage defence. Nature, 616:326-331, 2023 Cited by PubMed: 36848932 DOI: 10.1038/s41586-023-05862-7 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2 Å)

Structure validation