8GET

R. hominis 2 beta-glucuronidase bound to norquetiapine-glucuronide

Summary for 8GET

Entry DOI	10.2210/pdb8get/pdb
Descriptor	beta-galactosidase, GLYCEROL, beta-D-glucopyranuronic acid, ... (5 entities in total)
Functional Keywords	beta-glucuronidase, inhibitor, glucuronide, hydrolase
Biological source	Roseburia hominis
Total number of polymer chains	4
Total formula weight	347276.17
Authors	Simpson, J.B.,Redinbo, M.R. (deposition date: 2023-03-07, release date: 2024-03-20, Last modification date: 2024-06-26)
Primary citation	Simpson, J.B.,Walker, M.E.,Sekela, J.J.,Ivey, S.M.,Jariwala, P.B.,Storch, C.M.,Kowalewski, M.E.,Graboski, A.L.,Lietzan, A.D.,Walton, W.G.,Davis, K.A.,Cloer, E.W.,Borlandelli, V.,Hsiao, Y.C.,Roberts, L.R.,Perlman, D.H.,Liang, X.,Overkleeft, H.S.,Bhatt, A.P.,Lu, K.,Redinbo, M.R. Gut microbial beta-glucuronidases influence endobiotic homeostasis and are modulated by diverse therapeutics. Cell Host Microbe, 32:925-944.e10, 2024 Cited by PubMed: 38754417 DOI: 10.1016/j.chom.2024.04.018 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.9 Å)

Structure validation