8GET
R. hominis 2 beta-glucuronidase bound to norquetiapine-glucuronide
Summary for 8GET
Entry DOI | 10.2210/pdb8get/pdb |
Descriptor | beta-galactosidase, GLYCEROL, beta-D-glucopyranuronic acid, ... (5 entities in total) |
Functional Keywords | beta-glucuronidase, inhibitor, glucuronide, hydrolase |
Biological source | Roseburia hominis |
Total number of polymer chains | 4 |
Total formula weight | 347276.17 |
Authors | Simpson, J.B.,Redinbo, M.R. (deposition date: 2023-03-07, release date: 2024-03-20, Last modification date: 2024-06-26) |
Primary citation | Simpson, J.B.,Walker, M.E.,Sekela, J.J.,Ivey, S.M.,Jariwala, P.B.,Storch, C.M.,Kowalewski, M.E.,Graboski, A.L.,Lietzan, A.D.,Walton, W.G.,Davis, K.A.,Cloer, E.W.,Borlandelli, V.,Hsiao, Y.C.,Roberts, L.R.,Perlman, D.H.,Liang, X.,Overkleeft, H.S.,Bhatt, A.P.,Lu, K.,Redinbo, M.R. Gut microbial beta-glucuronidases influence endobiotic homeostasis and are modulated by diverse therapeutics. Cell Host Microbe, 32:925-944.e10, 2024 Cited by PubMed: 38754417DOI: 10.1016/j.chom.2024.04.018 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.9 Å) |
Structure validation
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