7URV
FMC63 scFv in complex with soluble CD19
Summary for 7URV
Entry DOI | 10.2210/pdb7urv/pdb |
EMDB information | 26719 |
Descriptor | B-lymphocyte antigen CD19, FMC63 single-chain variable fragment (2 entities in total) |
Functional Keywords | complex, car-t, protein binding |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 2 |
Total formula weight | 54101.84 |
Authors | Meyerson, J.,He, C. (deposition date: 2022-04-22, release date: 2023-02-15, Last modification date: 2023-03-15) |
Primary citation | He, C.,Mansilla-Soto, J.,Khanra, N.,Hamieh, M.,Bustos, V.,Paquette, A.J.,Garcia Angus, A.,Shore, D.M.,Rice, W.J.,Khelashvili, G.,Sadelain, M.,Meyerson, J.R. CD19 CAR antigen engagement mechanisms and affinity tuning. Sci Immunol, 8:eadf1426-eadf1426, 2023 Cited by PubMed: 36867678DOI: 10.1126/sciimmunol.adf1426 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.05 Å) |
Structure validation
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