7URV

FMC63 scFv in complex with soluble CD19

Summary for 7URV

• Entry DOI: 10.2210/pdb7urv/pdb
• EMDB information: 26719
• Descriptor: B-lymphocyte antigen CD19, FMC63 single-chain variable fragment (2 entities in total)
• Functional Keywords: complex, car-t, protein binding
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 2
• Total formula weight: 54101.84

Authors

Meyerson, J.,He, C. (deposition date: 2022-04-22, release date: 2023-02-15, Last modification date: 2023-03-15)

• Primary citation: He, C.,Mansilla-Soto, J.,Khanra, N.,Hamieh, M.,Bustos, V.,Paquette, A.J.,Garcia Angus, A.,Shore, D.M.,Rice, W.J.,Khelashvili, G.,Sadelain, M.,Meyerson, J.R.; CD19 CAR antigen engagement mechanisms and affinity tuning.; Sci Immunol, 8:eadf1426-eadf1426, 2023; PubMed: 36867678; DOI: 10.1126/sciimmunol.adf1426

Experimental method

ELECTRON MICROSCOPY (3.05 Å)