6ZVF
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5MHH
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6GR0
| Petrobactin-binding engineered lipocalin in complex with gallium-petrobactin | Descriptor: | 4-[4-[3-[[3,4-bis(oxidanyl)phenyl]carbonylamino]propylamino]butylamino]-2-[2-[4-[3-[[3,4-bis(oxidanyl)phenyl]carbonylamino]propylamino]butylamino]-2-oxidanylidene-ethyl]-2-oxidanyl-4-oxidanylidene-butanoic acid, GALLIUM (III) ION, Neutrophil gelatinase-associated lipocalin | Authors: | Skerra, A, Eichinger, A. | Deposit date: | 2018-06-08 | Release date: | 2018-08-15 | Last modified: | 2024-11-06 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Reprogramming Human Siderocalin To Neutralize Petrobactin, the Essential Iron Scavenger of Anthrax Bacillus. Angew. Chem. Int. Ed. Engl., 57, 2018
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6GQZ
| Petrobactin-binding engineered lipocalin without ligand | Descriptor: | Neutrophil gelatinase-associated lipocalin | Authors: | Skerra, A, Eichinger, A. | Deposit date: | 2018-06-08 | Release date: | 2018-08-15 | Last modified: | 2024-11-13 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Reprogramming Human Siderocalin To Neutralize Petrobactin, the Essential Iron Scavenger of Anthrax Bacillus. Angew. Chem. Int. Ed. Engl., 57, 2018
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6QBB
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6QSY
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6QMU
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6QW4
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6Z2C
| Engineered lipocalin C3A5 in complex with a transition state analog | Descriptor: | 1,7,8,9,10,10-hexachloro-4-carboxypentyl-4-aza-tricyclo[5.2.1.0(2,6)]dec-8-ene-3,5-dione, Neutrophil gelatinase-associated lipocalin | Authors: | Skerra, A, Eichinger, A. | Deposit date: | 2020-05-15 | Release date: | 2021-05-26 | Last modified: | 2024-11-20 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structure of an engineered lipocalin that catalyzes a Diels-Alder reaction To be published
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6Z6Z
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3P7F
| Structure of the human Langerin carbohydrate recognition domain | Descriptor: | C-type lectin domain family 4 member K, CALCIUM ION | Authors: | Skerra, A, Schiefner, A. | Deposit date: | 2010-10-12 | Release date: | 2010-11-03 | Last modified: | 2024-10-09 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | The carbohydrate recognition domain of Langerin reveals high structural similarity with the one of DC-SIGN but an additional, calcium-independent sugar-binding site. Mol.Immunol., 45, 2008
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3P7G
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6SOK
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6TIP
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6SOS
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5NBW
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5NKN
| Crystal structure of an Anticalin-colchicine complex | Descriptor: | N-[(7S)-1,2,3,10-tetramethoxy-9-oxo-6,7-dihydro-5H-benzo[d]heptalen-7-yl]ethanamide, Neutrophil gelatinase-associated lipocalin | Authors: | Skerra, A, Eichinger, A, Barkovskiy, M. | Deposit date: | 2017-03-31 | Release date: | 2018-04-04 | Last modified: | 2024-10-23 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | An engineered lipocalin that tightly complexes the plant poison colchicine for use as antidote and in bioanalytical applications. Biol. Chem., 400, 2019
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3P7H
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8B50
| Crystal structure of a Fab fragment in complex with L-hydroxycoumarylalanine | Descriptor: | (2~{S})-2-azanyl-3-(7-oxidanyl-2-oxidanylidene-chromen-4-yl)propanoic acid, Fab fragment K12F9-22 - heavy chain, Fab fragment K12F9-22 - light chain, ... | Authors: | Meining, W, Eichinger, A, Skerra, A. | Deposit date: | 2022-09-21 | Release date: | 2023-10-04 | Last modified: | 2024-11-13 | Method: | X-RAY DIFFRACTION (1.67 Å) | Cite: | Preparation and characterization of monoclonal antibodies against a non natural amino acid carrying the 7-hydroxycoumarin side chain To be published
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3BX7
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4MVK
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1GPO
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7P85
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6I9Q
| Structure of the mouse CD98 heavy chain ectodomain | Descriptor: | 1,2-ETHANEDIOL, 4F2 cell-surface antigen heavy chain, CHLORIDE ION | Authors: | Schiefner, A, Deuschle, F.-C, Skerra, A. | Deposit date: | 2018-11-24 | Release date: | 2019-04-17 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structural differences between the ectodomains of murine and human CD98hc. Proteins, 87, 2019
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2VO9
| CRYSTAL STRUCTURE OF THE ENZYMATICALLY ACTIVE DOMAIN OF THE LISTERIA MONOCYTOGENES BACTERIOPHAGE 500 ENDOLYSIN PLY500 | Descriptor: | L-ALANYL-D-GLUTAMATE PEPTIDASE, SULFATE ION, ZINC ION | Authors: | Korndoerfer, I.P, Kanitz, A, Skerra, A. | Deposit date: | 2008-02-09 | Release date: | 2008-02-19 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structural Analysis of the L-Alanoyl-D-Glutamate Endopeptidase Domain of Listeria Bacteriophage Endolysin Ply500 Reveals a New Member of the Las Peptidase Family. Acta Crystallogr.,Sect.D, 64, 2008
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