6GR0

Petrobactin-binding engineered lipocalin in complex with gallium-petrobactin

Summary for 6GR0

Entry DOI	10.2210/pdb6gr0/pdb
Descriptor	Neutrophil gelatinase-associated lipocalin, 4-[4-[3-[[3,4-bis(oxidanyl)phenyl]carbonylamino]propylamino]butylamino]-2-[2-[4-[3-[[3,4-bis(oxidanyl)phenyl]carbonylamino]propylamino]butylamino]-2-oxidanylidene-ethyl]-2-oxidanyl-4-oxidanylidene-butanoic acid, GALLIUM (III) ION, ... (4 entities in total)
Functional Keywords	anticalin, beta-barrel, petrobactin, lcn2, lipocalin, ngal, protein engineering, transport protein
Biological source	Homo sapiens (Human)
Total number of polymer chains	3
Total formula weight	65202.57
Authors	Skerra, A.,Eichinger, A. (deposition date: 2018-06-08, release date: 2018-08-15, Last modification date: 2024-01-17)
Primary citation	Dauner, M.,Eichinger, A.,Lucking, G.,Scherer, S.,Skerra, A. Reprogramming Human Siderocalin To Neutralize Petrobactin, the Essential Iron Scavenger of Anthrax Bacillus. Angew. Chem. Int. Ed. Engl., 57:14619-14623, 2018 Cited by PubMed: 30063283 DOI: 10.1002/anie.201807442 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.5 Å)

Structure validation