6ZVF
Crystal structure of the recombinant Fab fragment derived from the hybridoma M3/38 in complex with a human Galectin-3 peptide
Summary for 6ZVF
Entry DOI | 10.2210/pdb6zvf/pdb |
Descriptor | Chimeric Fab M3/38 (L,H), Galectin-3, ... (4 entities in total) |
Functional Keywords | antibody, fab fragment, peptide epitope, protein engineering, immune system |
Biological source | Rattus norvegicus More |
Total number of polymer chains | 3 |
Total formula weight | 49203.38 |
Authors | Skerra, A.,Eichinger, A. (deposition date: 2020-07-24, release date: 2021-04-14, Last modification date: 2024-01-31) |
Primary citation | Peplau, E.,De Rose, F.,Eichinger, A.,Reder, S.,Mittelhauser, M.,Scafetta, G.,Schwaiger, M.,Weber, W.A.,Bartolazzi, A.,D'Alessandria, C.,Skerra, A. Effective rational humanization of a PASylated anti-galectin-3 Fab for the sensitive PET imaging of thyroid cancer in vivo. Sci Rep, 11:7358-7358, 2021 Cited by PubMed: 33795750DOI: 10.1038/s41598-021-86641-0 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.9 Å) |
Structure validation
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