6Z2C

Engineered lipocalin C3A5 in complex with a transition state analog

Summary for 6Z2C

• Entry DOI: 10.2210/pdb6z2c/pdb
• Descriptor: Neutrophil gelatinase-associated lipocalin, 1,7,8,9,10,10-hexachloro-4-carboxypentyl-4-aza-tricyclo[5.2.1.0(2,6)]dec-8-ene-3,5-dione (3 entities in total)
• Functional Keywords: anticalin, beta-barrel, catalysis, diels-alder reaction, lcn2, lipocalin, ngal, protein engineering, transition state analog, protein binding
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 3
• Total formula weight: 66911.48

Authors

Skerra, A.,Eichinger, A. (deposition date: 2020-05-15, release date: 2021-05-26, Last modification date: 2024-01-24)

• Primary citation: Eichinger, A.,Skerra, A.; Structure of an engineered lipocalin that catalyzes a Diels-Alder reaction; To be published,

Experimental method

X-RAY DIFFRACTION (1.8 Å)