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3P7F

Structure of the human Langerin carbohydrate recognition domain

Replaces:  3BBS
Summary for 3P7F
Entry DOI10.2210/pdb3p7f/pdb
Related3P7G 3P7H
DescriptorC-type lectin domain family 4 member K, CALCIUM ION (3 entities in total)
Functional Keywordsc-type lectin, membrane protein, glycoprotein, langerin, dc-sign, carbohydrate binding protein, calcium binding, sugar binding, immune system, langerhans cells, cd207
Biological sourceHomo sapiens (human)
Cellular locationMembrane; Single-pass type II membrane protein: Q9UJ71
Total number of polymer chains4
Total formula weight67383.26
Authors
Skerra, A.,Schiefner, A. (deposition date: 2010-10-12, release date: 2010-11-03, Last modification date: 2023-09-06)
Primary citationChatwell, L.,Holla, A.,Kaufer, B.B.,Skerra, A.
The carbohydrate recognition domain of Langerin reveals high structural similarity with the one of DC-SIGN but an additional, calcium-independent sugar-binding site.
Mol.Immunol., 45:1981-1994, 2008
Cited by
PubMed: 18061677
DOI: 10.1016/j.molimm.2007.10.030
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.5 Å)
Structure validation

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