6Z6Z

Crystal structure of an Anticalin directed towards colchicine without ligand

Summary for 6Z6Z

Entry DOI	10.2210/pdb6z6z/pdb
Related	5NKN
Descriptor	Neutrophil gelatinase-associated lipocalin, CALCIUM ION (3 entities in total)
Functional Keywords	anticalin, beta-barrel, colchicine, conformation change, induced fit, lcn2, lipocalin, ngal, protein engineering, transport protein
Biological source	Homo sapiens (Human)
Total number of polymer chains	1
Total formula weight	21535.48
Authors	Skerra, A.,Eichinger, A. (deposition date: 2020-05-29, release date: 2021-06-09, Last modification date: 2024-10-16)
Primary citation	Ilyukhina, E.,Eichinger, A.,Skerra, A. Structural rearrangement in the ligand pocket of Colchicalin upon Colchicine binding To be published,
Experimental method	X-RAY DIFFRACTION (1.78 Å)

Structure validation