Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help
PDB: 98 results

6ZVF
DownloadVisualize
BU of 6zvf by Molmil
Crystal structure of the recombinant Fab fragment derived from the hybridoma M3/38 in complex with a human Galectin-3 peptide
Descriptor: Chimeric Fab M3/38 (L,H), Galectin-3
Authors:Skerra, A, Eichinger, A.
Deposit date:2020-07-24
Release date:2021-04-14
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Effective rational humanization of a PASylated anti-galectin-3 Fab for the sensitive PET imaging of thyroid cancer in vivo.
Sci Rep, 11, 2021
6GR0
DownloadVisualize
BU of 6gr0 by Molmil
Petrobactin-binding engineered lipocalin in complex with gallium-petrobactin
Descriptor: 4-[4-[3-[[3,4-bis(oxidanyl)phenyl]carbonylamino]propylamino]butylamino]-2-[2-[4-[3-[[3,4-bis(oxidanyl)phenyl]carbonylamino]propylamino]butylamino]-2-oxidanylidene-ethyl]-2-oxidanyl-4-oxidanylidene-butanoic acid, GALLIUM (III) ION, Neutrophil gelatinase-associated lipocalin
Authors:Skerra, A, Eichinger, A.
Deposit date:2018-06-08
Release date:2018-08-15
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Reprogramming Human Siderocalin To Neutralize Petrobactin, the Essential Iron Scavenger of Anthrax Bacillus.
Angew. Chem. Int. Ed. Engl., 57, 2018
6GQZ
DownloadVisualize
BU of 6gqz by Molmil
Petrobactin-binding engineered lipocalin without ligand
Descriptor: Neutrophil gelatinase-associated lipocalin
Authors:Skerra, A, Eichinger, A.
Deposit date:2018-06-08
Release date:2018-08-15
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Reprogramming Human Siderocalin To Neutralize Petrobactin, the Essential Iron Scavenger of Anthrax Bacillus.
Angew. Chem. Int. Ed. Engl., 57, 2018
6Z2C
DownloadVisualize
BU of 6z2c by Molmil
Engineered lipocalin C3A5 in complex with a transition state analog
Descriptor: 1,7,8,9,10,10-hexachloro-4-carboxypentyl-4-aza-tricyclo[5.2.1.0(2,6)]dec-8-ene-3,5-dione, Neutrophil gelatinase-associated lipocalin
Authors:Skerra, A, Eichinger, A.
Deposit date:2020-05-15
Release date:2021-05-26
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structure of an engineered lipocalin that catalyzes a Diels-Alder reaction
To be published
6QMU
DownloadVisualize
BU of 6qmu by Molmil
A tetrahedral boronic acid diester formed by a non-natural amino acid in the ligand pocket of an engineered lipocalin
Descriptor: 3-nitrophenol, Neutrophil gelatinase-associated lipocalin
Authors:Skerra, A, Eichinger, A.
Deposit date:2019-02-08
Release date:2019-08-28
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.98 Å)
Cite:A Tetrahedral Boronic Acid Diester Formed by an Unnatural Amino Acid in the Ligand Pocket of an Engineered Lipocalin.
Chembiochem, 21, 2020
6Z6Z
DownloadVisualize
BU of 6z6z by Molmil
Crystal structure of an Anticalin directed towards colchicine without ligand
Descriptor: CALCIUM ION, Neutrophil gelatinase-associated lipocalin
Authors:Skerra, A, Eichinger, A.
Deposit date:2020-05-29
Release date:2021-06-09
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.78 Å)
Cite:Structural rearrangement in the ligand pocket of Colchicalin upon Colchicine binding
To be published
6QSY
DownloadVisualize
BU of 6qsy by Molmil
Engineered streptavidin variant (H--WY) in complex with the Strep-tag II peptide
Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Strep-tag II peptide, Streptavidin, ...
Authors:Skerra, A, Eichinger, A.
Deposit date:2019-02-22
Release date:2020-03-18
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:The Role of Changing Loop Conformations in Streptavidin Versions Engineered for High-affinity Binding of the Strep-tag II Peptide.
J.Mol.Biol., 433, 2021
6QBB
DownloadVisualize
BU of 6qbb by Molmil
Engineered streptavidin variant (ENAGY) in complex with the Strep-tag II peptide
Descriptor: Strep-tag II peptide, Streptavidin
Authors:Skerra, A, Eichinger, A.
Deposit date:2018-12-20
Release date:2020-01-29
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.52 Å)
Cite:The Role of Changing Loop Conformations in Streptavidin Versions Engineered for High-affinity Binding of the Strep-tag II Peptide.
J.Mol.Biol., 433, 2021
6QW4
DownloadVisualize
BU of 6qw4 by Molmil
Engineered streptavidin variant (ACGR) in complex with the Strep-tag II peptide
Descriptor: Strep-tag II peptide, Streptavidin
Authors:Skerra, A, Eichinger, A.
Deposit date:2019-03-05
Release date:2020-03-25
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:The Role of Changing Loop Conformations in Streptavidin Versions Engineered for High-affinity Binding of the Strep-tag II Peptide.
J.Mol.Biol., 433, 2021
3P7G
DownloadVisualize
BU of 3p7g by Molmil
Structure of the human Langerin carbohydrate recognition domain in complex with mannose
Descriptor: C-type lectin domain family 4 member K, CALCIUM ION, alpha-D-mannopyranose
Authors:Skerra, A, Schiefner, A.
Deposit date:2010-10-12
Release date:2010-11-03
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:The carbohydrate recognition domain of Langerin reveals high structural similarity with the one of DC-SIGN but an additional, calcium-independent sugar-binding site.
Mol.Immunol., 45, 2008
6SOK
DownloadVisualize
BU of 6sok by Molmil
Engineered streptavidin variant (VTAR) in complex with the Twin-Strep-tag peptide
Descriptor: AMINO GROUP, Streptavidin, Twin-Strep-tag peptide
Authors:Skerra, A, Eichinger, A.
Deposit date:2019-08-29
Release date:2020-09-09
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.96 Å)
Cite:The Role of Changing Loop Conformations in Streptavidin Versions Engineered for High-affinity Binding of the Strep-tag II Peptide.
J.Mol.Biol., 433, 2021
3P7F
DownloadVisualize
BU of 3p7f by Molmil
Structure of the human Langerin carbohydrate recognition domain
Descriptor: C-type lectin domain family 4 member K, CALCIUM ION
Authors:Skerra, A, Schiefner, A.
Deposit date:2010-10-12
Release date:2010-11-03
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:The carbohydrate recognition domain of Langerin reveals high structural similarity with the one of DC-SIGN but an additional, calcium-independent sugar-binding site.
Mol.Immunol., 45, 2008
6TIP
DownloadVisualize
BU of 6tip by Molmil
Engineered streptavidin variant (YNAFM) in complex with the Strep-tag II peptide
Descriptor: AMINO GROUP, Strep-tag II peptide, Streptavidin
Authors:Skerra, A, Eichinger, A.
Deposit date:2019-11-22
Release date:2020-12-02
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:The Role of Changing Loop Conformations in Streptavidin Versions Engineered for High-affinity Binding of the Strep-tag II Peptide.
J.Mol.Biol., 433, 2021
6SOS
DownloadVisualize
BU of 6sos by Molmil
Engineered streptavidin variant (ENAGY) in complex with the Twin-Strep-tag peptide
Descriptor: Streptavidin, Twin-Strep-tag peptide
Authors:Skerra, A, Eichinger, A.
Deposit date:2019-08-29
Release date:2020-09-09
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:The Role of Changing Loop Conformations in Streptavidin Versions Engineered for High-affinity Binding of the Strep-tag II Peptide.
J.Mol.Biol., 433, 2021
3P7H
DownloadVisualize
BU of 3p7h by Molmil
Structure of the human Langerin carbohydrate recognition domain in complex with maltose
Descriptor: C-type lectin domain family 4 member K, CALCIUM ION, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose
Authors:Skerra, A, Schiefner, A.
Deposit date:2010-10-12
Release date:2010-11-03
Last modified:2023-12-06
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:The carbohydrate recognition domain of Langerin reveals high structural similarity with the one of DC-SIGN but an additional, calcium-independent sugar-binding site.
Mol.Immunol., 45, 2008
5MHH
DownloadVisualize
BU of 5mhh by Molmil
Crystal structure of engineered human lipocalin 2 carrying p-boronophenylalanine at position 36
Descriptor: Neutrophil gelatinase-associated lipocalin, SULFATE ION
Authors:Skerra, A, Eichinger, A.
Deposit date:2016-11-24
Release date:2017-10-11
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2 Å)
Cite:Rational Design of an Anticalin-Type Sugar-Binding Protein Using a Genetically Encoded Boronate Side Chain.
ACS Synth Biol, 6, 2017
5NBW
DownloadVisualize
BU of 5nbw by Molmil
Crystal structure of the Fab fragment 22F12 in complex with 3-hydroxybenzo[a]pyrene
Descriptor: Fab 22F12 (A,B), Fab 22F12 (L,H), benzo[a]pyren-3-ol
Authors:Skerra, A, Eichinger, A.
Deposit date:2017-03-02
Release date:2017-06-28
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Tight Molecular Recognition of Benzo[a]pyrene by a High-Affinity Antibody.
Angew. Chem. Int. Ed. Engl., 56, 2017
5NKN
DownloadVisualize
BU of 5nkn by Molmil
Crystal structure of an Anticalin-colchicine complex
Descriptor: N-[(7S)-1,2,3,10-tetramethoxy-9-oxo-6,7-dihydro-5H-benzo[d]heptalen-7-yl]ethanamide, Neutrophil gelatinase-associated lipocalin
Authors:Skerra, A, Eichinger, A, Barkovskiy, M.
Deposit date:2017-03-31
Release date:2018-04-04
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:An engineered lipocalin that tightly complexes the plant poison colchicine for use as antidote and in bioanalytical applications.
Biol. Chem., 400, 2019
1N0S
DownloadVisualize
BU of 1n0s by Molmil
ENGINEERED LIPOCALIN FLUA IN COMPLEX WITH FLUORESCEIN
Descriptor: 2-(6-HYDROXY-3-OXO-3H-XANTHEN-9-YL)-BENZOIC ACID, Bilin-binding protein, SULFATE ION
Authors:Korndoerfer, I.P, Skerra, A.
Deposit date:2002-10-15
Release date:2003-08-05
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystallographic analysis of an "anticalin" with tailored specificity for fluorescein reveals high structural plasticity of the lipocalin loop region.
Proteins, 53, 2003
3DDY
DownloadVisualize
BU of 3ddy by Molmil
Structure of lumazine protein, an optical transponder of luminescent bacteria
Descriptor: Lumazine protein, RIBOFLAVIN
Authors:Chatwell, L, Illarionova, V, Illarionov, B, Skerra, A, Bacher, A, Fischer, M.
Deposit date:2008-06-07
Release date:2008-07-01
Last modified:2024-05-29
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structure of lumazine protein, an optical transponder of luminescent bacteria.
J.Mol.Biol., 382, 2008
4GH7
DownloadVisualize
BU of 4gh7 by Molmil
Crystal structure of Anticalin N7A in complex with oncofetal fibronectin fragment Fn7B8
Descriptor: Fibronectin, Neutrophil gelatinase-associated lipocalin
Authors:Schiefner, A, Gebauer, M, Skerra, A.
Deposit date:2012-08-07
Release date:2012-12-26
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Combinatorial design of an Anticalin directed against the extra-domain b for the specific targeting of oncofetal fibronectin
J.Mol.Biol., 425, 2013
1GPO
DownloadVisualize
BU of 1gpo by Molmil
CRYSTAL STRUCTURE OF THE RATIONALLY DESIGNED ANTIBODY M41 AS A FAB FRAGMENT
Descriptor: ANTIBODY M41, SULFATE ION
Authors:Schiweck, W, Skerra, A.
Deposit date:1997-03-27
Release date:1998-04-01
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:The rational construction of an antibody against cystatin: lessons from the crystal structure of an artificial Fab fragment.
J.Mol.Biol., 268, 1997
8B50
DownloadVisualize
BU of 8b50 by Molmil
Crystal structure of a Fab fragment in complex with L-hydroxycoumarylalanine
Descriptor: (2~{S})-2-azanyl-3-(7-oxidanyl-2-oxidanylidene-chromen-4-yl)propanoic acid, Fab fragment K12F9-22 - heavy chain, Fab fragment K12F9-22 - light chain, ...
Authors:Meining, W, Eichinger, A, Skerra, A.
Deposit date:2022-09-21
Release date:2023-10-04
Method:X-RAY DIFFRACTION (1.67 Å)
Cite:Preparation and characterization of monoclonal antibodies against a non natural amino acid carrying the 7-hydroxycoumarin side chain
To be published
3LYA
DownloadVisualize
BU of 3lya by Molmil
Crystal structure of the periplasmic domain of CadC in the presence of K2ReCl6
Descriptor: Transcriptional activator cadC, rhenium (IV) hexachloride
Authors:Eichinger, A, Skerra, A.
Deposit date:2010-02-26
Release date:2011-02-09
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structure of the sensory domain of Escherichia coli CadC, a member of the ToxR-like protein family.
Protein Sci., 20, 2011
3LRH
DownloadVisualize
BU of 3lrh by Molmil
Structure of anti-huntingtin VL domain in complex with huntingtin peptide
Descriptor: Huntingtin, anti-huntingtin VL domain
Authors:Schiefner, A, Chatwell, L, Skerra, A.
Deposit date:2010-02-11
Release date:2011-02-23
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:A Disulfide-Free Single-Domain V(L) Intrabody with Blocking Activity towards Huntingtin Reveals a Novel Mode of Epitope Recognition.
J.Mol.Biol., 414, 2011

 

1234>

222624

PDB entries from 2024-07-17

PDB statisticsPDBj update infoContact PDBjnumon