3J1W
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3j1w by Molmil](/molmil-images/mine/3j1w) | |
3J1V
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3j1v by Molmil](/molmil-images/mine/3j1v) | |
3J1X
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3j1x by Molmil](/molmil-images/mine/3j1x) | A refined model of the prototypical Salmonella typhimurium T3SS basal body reveals the molecular basis for its assembly | 分子名称: | Protein PrgH | 著者 | Sgourakis, N.G, Bergeron, J.R.C, Worrall, L.J, Strynadka, N.C.J, Baker, D. | 登録日 | 2012-07-10 | 公開日 | 2013-05-22 | 最終更新日 | 2024-02-21 | 実験手法 | ELECTRON MICROSCOPY (11.7 Å) | 主引用文献 | A Refined Model of the Prototypical Salmonella SPI-1 T3SS Basal Body Reveals the Molecular Basis for Its Assembly. Plos Pathog., 9, 2013
|
|
2KDI
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2kdi by Molmil](/molmil-images/mine/2kdi) | Solution structure of a Ubiquitin/UIM fusion protein | 分子名称: | Ubiquitin, Vacuolar protein sorting-associated protein 27 fusion protein | 著者 | Sgourakis, N.G, Patel, M.M, Garcia, A.E, Makhatadze, G.I, McCallum, S.A. | 登録日 | 2009-01-09 | 公開日 | 2010-02-09 | 最終更新日 | 2024-05-08 | 実験手法 | SOLUTION NMR | 主引用文献 | Conformational Dynamics and Structural Plasticity Play Critical Roles in the Ubiquitin Recognition of a UIM Domain. J.Mol.Biol., 396, 2010
|
|
2MPZ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2mpz by Molmil](/molmil-images/mine/2mpz) | |
2MIZ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2miz by Molmil](/molmil-images/mine/2miz) | |
6E5C
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6e5c by Molmil](/molmil-images/mine/6e5c) | Solution NMR structure of a de novo designed double-stranded beta-helix | 分子名称: | De novo beta protein | 著者 | Marcos, E, Chidyausiku, T.M, McShan, A, Evangelidis, T, Nerli, S, Sgourakis, N, Tripsianes, K, Baker, D. | 登録日 | 2018-07-19 | 公開日 | 2018-11-07 | 最終更新日 | 2024-05-01 | 実験手法 | SOLUTION NMR | 主引用文献 | De novo design of a non-local beta-sheet protein with high stability and accuracy. Nat. Struct. Mol. Biol., 25, 2018
|
|
6DMP
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6dmp by Molmil](/molmil-images/mine/6dmp) | De Novo Design of a Protein Heterodimer with Specificity Mediated by Hydrogen Bond Networks | 分子名称: | Designed orthogonal protein DHD13_XAAA_A, Designed orthogonal protein DHD13_XAAA_B | 著者 | Chen, Z, Flores-Solis, D, Sgourakis, N.G, Baker, D. | 登録日 | 2018-06-05 | 公開日 | 2018-12-19 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | Programmable design of orthogonal protein heterodimers. Nature, 565, 2019
|
|
5VZ5
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5vz5 by Molmil](/molmil-images/mine/5vz5) | Crystal structure of an anaplastic lymphoma kinase-derived neuroblastoma tumor antigen bound to the Human Major Histocompatibility Complex Class I molecule HLA-B*1501 | 分子名称: | Beta-2-microglobulin, GLYCEROL, HLA class I histocompatibility antigen, ... | 著者 | Toor, J, Rao, A.A, Salama, S, Tripathi, S, Haussler, D, Sgourakis, N.G. | 登録日 | 2017-05-26 | 公開日 | 2018-03-21 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.5901 Å) | 主引用文献 | A Recurrent Mutation in Anaplastic Lymphoma Kinase with Distinct Neoepitope Conformations. Front Immunol, 9, 2018
|
|
5WOX
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5wox by Molmil](/molmil-images/mine/5wox) | |
5WOZ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5woz by Molmil](/molmil-images/mine/5woz) | |
7RNO
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7rno by Molmil](/molmil-images/mine/7rno) | Model of the Ac-6-FP/hpMR1/bB2m/TAPBPR complex from integrated docking, NMR and restrained MD | 分子名称: | Beta-2-microglobulin, Major histocompatibility complex class I-related gene protein, N-(6-formyl-4-oxo-3,4-dihydropteridin-2-yl)acetamide, ... | 著者 | McShan, A.C, Sgourakis, N.G. | 登録日 | 2021-07-29 | 公開日 | 2022-05-11 | 最終更新日 | 2022-08-10 | 実験手法 | SOLUTION NMR | 主引用文献 | TAPBPR employs a ligand-independent docking mechanism to chaperone MR1 molecules. Nat.Chem.Biol., 18, 2022
|
|
6OSW
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6osw by Molmil](/molmil-images/mine/6osw) | An order-to-disorder structural switch activates the FoxM1 transcription factor | 分子名称: | Forkhead box M1 | 著者 | Marceau, A.H, Rubin, S.M, Nerli, S, McShane, A.C, Sgourakis, N.G. | 登録日 | 2019-05-02 | 公開日 | 2019-05-29 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | An order-to-disorder structural switch activates the FoxM1 transcription factor. Elife, 8, 2019
|
|
8SBK
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8sbk by Molmil](/molmil-images/mine/8sbk) | Structure of HLA-A*24:02 in complex with peptide, LYLPVRVLI (ATG2A). | 分子名称: | 1,2-ETHANEDIOL, Beta-2-microglobulin, LEU-TYR-LEU-PRO-VAL-ARG-VAL-LEU-ILE, ... | 著者 | Mallik, L, Young, M.C, Sgourakis, N.G. | 登録日 | 2023-04-03 | 公開日 | 2023-12-06 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Structural principles of peptide-centric chimeric antigen receptor recognition guide therapeutic expansion. Sci Immunol, 8, 2023
|
|
8SBL
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8sbl by Molmil](/molmil-images/mine/8sbl) | Structure of HLA-A*24:02 in complex with peptide, LYLPVRVLI | 分子名称: | Beta-2-microglobulin, LEU-TYR-LEU-PRO-VAL-ARG-VAL-LEU-ILE, MHC class I antigen | 著者 | Mallik, L, Young, M.C, Sgourakis, N.G. | 登録日 | 2023-04-03 | 公開日 | 2023-12-06 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Structural principles of peptide-centric chimeric antigen receptor recognition guide therapeutic expansion. Sci Immunol, 8, 2023
|
|
5TXS
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5txs by Molmil](/molmil-images/mine/5txs) | Crystal structure of an anaplastic lymphoma kinase-derived neuroblastoma tumor antigen bound to the Human Major Histocompatibility Complex Class I molecule HLA-B*1501 | 分子名称: | Beta-2-microglobulin, HLA class I histocompatibility antigen, B-15 alpha chain, ... | 著者 | Toor, J, Rao, A.A, Salama, S, Tripathi, S, Haussler, D, Sgourakis, N.G. | 登録日 | 2016-11-17 | 公開日 | 2017-11-29 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (1.697 Å) | 主引用文献 | A Recurrent Mutation in Anaplastic Lymphoma Kinase with Distinct Neoepitope Conformations. Front Immunol, 9, 2018
|
|
8EK5
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8ek5 by Molmil](/molmil-images/mine/8ek5) | Engineered scFv 10LH bound to PHOX2B/HLA-A24:02 | 分子名称: | 10LH single chain fragment variable (scFv), Beta-2-microglobulin, GLYCEROL, ... | 著者 | Garfinkle, S.E, Florio, T.J, Sgourakis, N.G. | 登録日 | 2022-09-20 | 公開日 | 2023-12-06 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.11 Å) | 主引用文献 | Structural principles of peptide-centric chimeric antigen receptor recognition guide therapeutic expansion. Sci Immunol, 8, 2023
|
|
8ERX
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8erx by Molmil](/molmil-images/mine/8erx) | Structure of chimeric HLA-A*11:01-A*02:01 bound to HIV-1 RT peptide | 分子名称: | Beta-2-microglobulin, HIV-1 RT, HLA-A*02:01 | 著者 | Florio, T.J, Ani, O, Young, M.C, Mallik, L, Sgourakis, N.G. | 登録日 | 2022-10-13 | 公開日 | 2023-01-25 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.07 Å) | 主引用文献 | Decoupling peptide binding from T cell receptor recognition with engineered chimeric MHC-I molecules. Front Immunol, 14, 2023
|
|
8ESH
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8esh by Molmil](/molmil-images/mine/8esh) | Structure of chimeric HLA-A*02:01 bound to CMV peptide | 分子名称: | Beta-2-microglobulin, CMV peptide, HLA-A*02:01 | 著者 | Florio, T.J, Ani, O, Young, M.C, Mallik, L, Sgourakis, N.G. | 登録日 | 2022-10-14 | 公開日 | 2023-01-25 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.72 Å) | 主引用文献 | Decoupling peptide binding from T cell receptor recognition with engineered chimeric MHC-I molecules. Front Immunol, 14, 2023
|
|
5WOT
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5wot by Molmil](/molmil-images/mine/5wot) | |
5WOY
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5woy by Molmil](/molmil-images/mine/5woy) | |
7RY6
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7ry6 by Molmil](/molmil-images/mine/7ry6) | Solution NMR structural bundle of the first cyclization domain from yersiniabactin synthetase (Cy1) impacted by dynamics | 分子名称: | HMWP2 nonribosomal peptide synthetase | 著者 | Kancherla, A.K, Mishra, S.H, Marincin, K.A, Nerli, S, Sgourakis, N.G, Dowling, D.P, Bouvignies, G, Frueh, D.P. | 登録日 | 2021-08-24 | 公開日 | 2022-07-13 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | Global protein dynamics as communication sensors in peptide synthetase domains. Sci Adv, 8, 2022
|
|
6B9K
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6b9k by Molmil](/molmil-images/mine/6b9k) | |
7MJ9
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7mj9 by Molmil](/molmil-images/mine/7mj9) | HLA-A*02:01 bound to Neuroblastoma Derived mutant IGFBPL1 peptide | 分子名称: | Beta-2-microglobulin, Insulin-like growth factor-binding protein-like 1 altered peptide, MHC class I antigen | 著者 | Toor, J.S, Tripathi, S.M, Truong, H.V, Yarmarkovich, M, Maris, J.M, Sgourakis, N.G. | 登録日 | 2021-04-19 | 公開日 | 2021-08-18 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | Cross-HLA targeting of intracellular oncoproteins with peptide-centric CARs. Nature, 599, 2021
|
|
7MJ6
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7mj6 by Molmil](/molmil-images/mine/7mj6) | HLA-A*02:01 bound to Neuroblastoma Derived IGFBPL1 peptide | 分子名称: | Beta-2-microglobulin, GLYCEROL, Insulin-like growth factor-binding protein-like 1 peptide, ... | 著者 | Toor, J.S, Tripathi, S.M, Truong, H.V, Yarmarkovich, M, Maris, J.M, Sgourakis, N.G. | 登録日 | 2021-04-19 | 公開日 | 2021-08-18 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Cross-HLA targeting of intracellular oncoproteins with peptide-centric CARs. Nature, 599, 2021
|
|