6DMP
De Novo Design of a Protein Heterodimer with Specificity Mediated by Hydrogen Bond Networks
Summary for 6DMP
Entry DOI | 10.2210/pdb6dmp/pdb |
NMR Information | BMRB: 30474 |
Descriptor | Designed orthogonal protein DHD13_XAAA_A, Designed orthogonal protein DHD13_XAAA_B (2 entities in total) |
Functional Keywords | de novo protein, computational design, coiled coil |
Biological source | synthetic construct More |
Total number of polymer chains | 2 |
Total formula weight | 19143.06 |
Authors | Chen, Z.,Flores-Solis, D.,Sgourakis, N.G.,Baker, D. (deposition date: 2018-06-05, release date: 2018-12-19, Last modification date: 2023-06-14) |
Primary citation | Chen, Z.,Boyken, S.E.,Jia, M.,Busch, F.,Flores-Solis, D.,Bick, M.J.,Lu, P.,VanAernum, Z.L.,Sahasrabuddhe, A.,Langan, R.A.,Bermeo, S.,Brunette, T.J.,Mulligan, V.K.,Carter, L.P.,DiMaio, F.,Sgourakis, N.G.,Wysocki, V.H.,Baker, D. Programmable design of orthogonal protein heterodimers. Nature, 565:106-111, 2019 Cited by PubMed: 30568301DOI: 10.1038/s41586-018-0802-y PDB entries with the same primary citation |
Experimental method | SOLUTION NMR |
Structure validation
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