8SBL

Structure of HLA-A*24:02 in complex with peptide, LYLPVRVLI

Summary for 8SBL

• Entry DOI: 10.2210/pdb8sbl/pdb
• Descriptor: MHC class I antigen, Beta-2-microglobulin, LEU-TYR-LEU-PRO-VAL-ARG-VAL-LEU-ILE (3 entities in total)
• Functional Keywords: major histocompatibility complex (mhc), immune system
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 12
• Total formula weight: 181730.46

Authors

Mallik, L.,Young, M.C.,Sgourakis, N.G. (deposition date: 2023-04-03, release date: 2023-12-06, Last modification date: 2023-12-13)

• Primary citation: Sun, Y.,Florio, T.J.,Gupta, S.,Young, M.C.,Marshall, Q.F.,Garfinkle, S.E.,Papadaki, G.F.,Truong, H.V.,Mycek, E.,Li, P.,Farrel, A.,Church, N.L.,Jabar, S.,Beasley, M.D.,Kiefel, B.R.,Yarmarkovich, M.,Mallik, L.,Maris, J.M.,Sgourakis, N.G.; Structural principles of peptide-centric chimeric antigen receptor recognition guide therapeutic expansion.; Sci Immunol, 8:eadj5792-eadj5792, 2023; PubMed: 38039376; DOI: 10.1126/sciimmunol.adj5792

Experimental method

X-RAY DIFFRACTION (3 Å)