7RY6

Solution NMR structural bundle of the first cyclization domain from yersiniabactin synthetase (Cy1) impacted by dynamics

Summary for 7RY6

• Entry DOI: 10.2210/pdb7ry6/pdb
• NMR Information: BMRB: 30943
• Descriptor: HMWP2 nonribosomal peptide synthetase (1 entity in total)
• Functional Keywords: heterocyclization, nonribosomal peptide synthetase, peptide bond formation, ligase
• Biological source: Yersinia pestis
• Total number of polymer chains: 1
• Total formula weight: 51914.56

Authors

Kancherla, A.K.,Mishra, S.H.,Marincin, K.A.,Nerli, S.,Sgourakis, N.G.,Dowling, D.P.,Bouvignies, G.,Frueh, D.P. (deposition date: 2021-08-24, release date: 2022-07-13, Last modification date: 2024-05-15)

• Primary citation: Mishra, S.H.,Kancherla, A.K.,Marincin, K.A.,Bouvignies, G.,Nerli, S.,Sgourakis, N.,Dowling, D.P.,Frueh, D.P.; Global protein dynamics as communication sensors in peptide synthetase domains.; Sci Adv, 8:eabn6549-eabn6549, 2022; PubMed: 35857508; DOI: 10.1126/sciadv.abn6549

Experimental method

SOLUTION NMR