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7RNO

Model of the Ac-6-FP/hpMR1/bB2m/TAPBPR complex from integrated docking, NMR and restrained MD

Summary for 7RNO
Entry DOI10.2210/pdb7rno/pdb
NMR InformationBMRB: 51044
DescriptorMajor histocompatibility complex class I-related gene protein, Beta-2-microglobulin, TAP binding protein-like variant, ... (4 entities in total)
Functional Keywordstapbpr, mr1, mhc-i, chaperones, adaptive immune system, antigen processing and presentation, immune system
Biological sourceHomo sapiens (Human)
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Total number of polymer chains3
Total formula weight86350.23
Authors
McShan, A.C.,Sgourakis, N.G. (deposition date: 2021-07-29, release date: 2022-05-11, Last modification date: 2022-08-10)
Primary citationMcShan, A.C.,Devlin, C.A.,Papadaki, G.F.,Sun, Y.,Green, A.I.,Morozov, G.I.,Burslem, G.M.,Procko, E.,Sgourakis, N.G.
TAPBPR employs a ligand-independent docking mechanism to chaperone MR1 molecules.
Nat.Chem.Biol., 18:859-868, 2022
Cited by
PubMed: 35725941
DOI: 10.1038/s41589-022-01049-9
PDB entries with the same primary citation
Experimental method
SOLUTION NMR
Structure validation

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