7MJ9
HLA-A*02:01 bound to Neuroblastoma Derived mutant IGFBPL1 peptide
Summary for 7MJ9
Entry DOI | 10.2210/pdb7mj9/pdb |
Descriptor | MHC class I antigen, Beta-2-microglobulin, Insulin-like growth factor-binding protein-like 1 altered peptide, ... (4 entities in total) |
Functional Keywords | lymphoma kinase-derived neuroblastoma tumor antigen, human major histocompatibility complex class i, mhc-i, complex, immune system |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 3 |
Total formula weight | 44994.21 |
Authors | Toor, J.S.,Tripathi, S.M.,Truong, H.V.,Yarmarkovich, M.,Maris, J.M.,Sgourakis, N.G. (deposition date: 2021-04-19, release date: 2021-08-18, Last modification date: 2023-10-18) |
Primary citation | Yarmarkovich, M.,Marshall, Q.F.,Warrington, J.M.,Premaratne, R.,Farrel, A.,Groff, D.,Li, W.,di Marco, M.,Runbeck, E.,Truong, H.,Toor, J.S.,Tripathi, S.,Nguyen, S.,Shen, H.,Noel, T.,Church, N.L.,Weiner, A.,Kendsersky, N.,Martinez, D.,Weisberg, R.,Christie, M.,Eisenlohr, L.,Bosse, K.R.,Dimitrov, D.S.,Stevanovic, S.,Sgourakis, N.G.,Kiefel, B.R.,Maris, J.M. Cross-HLA targeting of intracellular oncoproteins with peptide-centric CARs. Nature, 599:477-484, 2021 Cited by PubMed: 34732890DOI: 10.1038/s41586-021-04061-6 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.75 Å) |
Structure validation
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