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PDB: 151 件

8QYJ
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BU of 8qyj by Molmil
Human 20S proteasome assembly structure 1
分子名称: Proteasome assembly chaperone 1, Proteasome assembly chaperone 2, Proteasome assembly chaperone 3, ...
著者Schulman, B.A, Hanna, J.W, Harper, J.W, Adolf, F, Du, J, Rawson, S.D, Walsh Jr, R.M, Goodall, E.A.
登録日2023-10-26
公開日2024-02-21
最終更新日2024-04-17
実験手法ELECTRON MICROSCOPY (2.73 Å)
主引用文献Visualizing chaperone-mediated multistep assembly of the human 20S proteasome.
Nat.Struct.Mol.Biol., 2024
8QYO
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BU of 8qyo by Molmil
Human proteasome 20S core particle
分子名称: Proteasome subunit alpha type-1, Proteasome subunit alpha type-2, Proteasome subunit alpha type-3, ...
著者Schulman, B.A, Hanna, J.W, Harper, J.W, Adolf, F, Du, J, Rawson, S.D, Walsh Jr, R.M, Goodall, E.A.
登録日2023-10-26
公開日2024-02-21
最終更新日2024-04-17
実験手法ELECTRON MICROSCOPY (2.84 Å)
主引用文献Visualizing chaperone-mediated multistep assembly of the human 20S proteasome.
Nat.Struct.Mol.Biol., 2024
8QYM
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BU of 8qym by Molmil
Human 20S proteasome assembly intermediate structure 3
分子名称: Proteasome assembly chaperone 1, Proteasome assembly chaperone 2, Proteasome maturation protein, ...
著者Schulman, B.A, Hanna, J.W, Harper, J.W, Adolf, F, Du, J, Rawson, S.D, Walsh Jr, R.M, Goodall, E.A.
登録日2023-10-26
公開日2024-02-21
最終更新日2024-04-17
実験手法ELECTRON MICROSCOPY (2.73 Å)
主引用文献Visualizing chaperone-mediated multistep assembly of the human 20S proteasome.
Nat.Struct.Mol.Biol., 2024
8QZ9
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BU of 8qz9 by Molmil
Human 20S proteasome assembly intermediate structure 4
分子名称: Proteasome assembly chaperone 1, Proteasome assembly chaperone 2, Proteasome maturation protein, ...
著者Schulman, B.A, Hanna, J.W, Harper, J.W, Adolf, F, Du, J, Rawson, S.D, Walsh Jr, R.M, Goodall, E.A.
登録日2023-10-26
公開日2024-02-21
最終更新日2024-04-17
実験手法ELECTRON MICROSCOPY (2.95 Å)
主引用文献Visualizing chaperone-mediated multistep assembly of the human 20S proteasome.
Nat.Struct.Mol.Biol., 2024
8QYS
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BU of 8qys by Molmil
Human preholo proteasome 20S core particle
分子名称: Proteasome assembly chaperone 1, Proteasome assembly chaperone 2, Proteasome maturation protein, ...
著者Schulman, B.A, Hanna, J.W, Harper, J.W, Adolf, F, Du, J, Rawson, S.D, Walsh Jr, R.M, Goodall, E.A.
登録日2023-10-26
公開日2024-02-21
最終更新日2024-04-17
実験手法ELECTRON MICROSCOPY (3.89 Å)
主引用文献Visualizing chaperone-mediated multistep assembly of the human 20S proteasome.
Nat.Struct.Mol.Biol., 2024
8QYL
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BU of 8qyl by Molmil
Human 20S proteasome assembly intermediate structure 2
分子名称: Proteasome assembly chaperone 1, Proteasome assembly chaperone 2, Proteasome maturation protein, ...
著者Schulman, B.A, Hanna, J.W, Harper, J.W, Adolf, F, Du, J, Rawson, S.D, Walsh Jr, R.M, Goodall, E.A.
登録日2023-10-26
公開日2024-02-21
最終更新日2024-04-17
実験手法ELECTRON MICROSCOPY (2.67 Å)
主引用文献Visualizing chaperone-mediated multistep assembly of the human 20S proteasome.
Nat.Struct.Mol.Biol., 2024
8QYN
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BU of 8qyn by Molmil
Human 20S proteasome assembly intermediate structure 5
分子名称: Proteasome assembly chaperone 1, Proteasome assembly chaperone 2, Proteasome maturation protein, ...
著者Schulman, B.A, Hanna, J.W, Harper, J.W, Adolf, F, Du, J, Rawson, S.D, Walsh Jr, R.M, Goodall, E.A.
登録日2023-10-26
公開日2024-02-21
最終更新日2024-04-17
実験手法ELECTRON MICROSCOPY (2.88 Å)
主引用文献Visualizing chaperone-mediated multistep assembly of the human 20S proteasome.
Nat.Struct.Mol.Biol., 2024
1FQV
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BU of 1fqv by Molmil
Insights into scf ubiquitin ligases from the structure of the skp1-skp2 complex
分子名称: SKP1, SKP2
著者Schulman, B.A, Carrano, A.C, Jeffrey, P.D, Bowen, Z, Kinnucan, E.R, Finnin, M.S, Elledge, S.J, Harper, J.W, Pagano, M, Pavletich, N.P.
登録日2000-09-06
公開日2000-11-29
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Insights into SCF ubiquitin ligases from the structure of the Skp1-Skp2 complex.
Nature, 408, 2000
1FS2
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BU of 1fs2 by Molmil
INSIGHTS INTO SCF UBIQUITIN LIGASES FROM THE STRUCTURE OF THE SKP1-SKP2 COMPLEX
分子名称: SKP1, SKP2
著者Schulman, B.A, Carrano, A.C, Jeffrey, P.D, Bowen, Z, Kinnucan, E.R.E, Finnin, M.S, Elledge, S.J, Harper, J.W, Pagano, M, Pavletich, N.P.
登録日2000-09-08
公開日2000-11-29
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Insights into SCF ubiquitin ligases from the structure of the Skp1-Skp2 complex.
Nature, 408, 2000
1FS1
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BU of 1fs1 by Molmil
INSIGHTS INTO SCF UBIQUITIN LIGASES FROM THE STRUCTURE OF THE SKP1-SKP2 COMPLEX
分子名称: CYCLIN A/CDK2-ASSOCIATED P19, CYCLIN A/CDK2-ASSOCIATED P45
著者Schulman, B.A, Carrano, A.C, Jeffrey, P.D, Bowen, Z, Kinnucan, E.R.E, Finnin, M.S, Elledge, S.J, Harper, J.W, Pagano, M, Pavletich, N.P.
登録日2000-09-08
公開日2000-11-29
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Insights into SCF ubiquitin ligases from the structure of the Skp1-Skp2 complex.
Nature, 408, 2000
3IVQ
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BU of 3ivq by Molmil
Structures of SPOP-Substrate Complexes: Insights into Molecular Architectures of BTB-Cul3 Ubiquitin Ligases: SPOPMATH-CiSBC2
分子名称: CiSBC2, Speckle-type POZ protein
著者Schulman, B.A, Miller, D.J, Calabrese, M.F, Seyedin, S.
登録日2009-09-01
公開日2009-10-20
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structures of SPOP-Substrate Complexes: Insights into Molecular Architectures of BTB-Cul3 Ubiquitin Ligases.
Mol.Cell, 36, 2009
3IVV
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BU of 3ivv by Molmil
Structures of SPOP-Substrate Complexes: Insights into Molecular Architectures of BTB-Cul3 Ubiquitin Ligases: SPOPMATH-PucSBC1_pep1
分子名称: PucSBC1, Speckle-type POZ protein
著者Schulman, B.A, Miller, D.J, Calabrese, M.F, Seyedin, S.
登録日2009-09-01
公開日2009-10-20
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.25 Å)
主引用文献Structures of SPOP-Substrate Complexes: Insights into Molecular Architectures of BTB-Cul3 Ubiquitin Ligases.
Mol.Cell, 36, 2009
3IVB
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BU of 3ivb by Molmil
Structures of SPOP-Substrate Complexes: Insights into Architectures of BTB-Cul3 Ubiquitin Ligases: SPOPMATH-MacroH2ASBCpep1
分子名称: CHLORIDE ION, Core histone macro-H2A.1, Speckle-type POZ protein, ...
著者Schulman, B.A, Miller, D.J, Calabrese, M.F, Seyedin, S.
登録日2009-08-31
公開日2009-10-20
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Structure 9
To be Published
8OIF
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BU of 8oif by Molmil
Structure of the UBE1L activating enzyme bound to ISG15 and UBE2L6
分子名称: ADENOSINE MONOPHOSPHATE, Ubiquitin-like modifier-activating enzyme 7, Ubiquitin-like protein ISG15, ...
著者Wallace, I, Kheewoong, B, Prabu, J.R, Vollrath, R, von Gronau, S, Schulman, B.A, Swatek, K.N.
登録日2023-03-22
公開日2023-12-13
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Insights into the ISG15 transfer cascade by the UBE1L activating enzyme.
Nat Commun, 14, 2023
7WUG
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BU of 7wug by Molmil
GID subcomplex: Gid12 bound Substrate Receptor Scaffolding module
分子名称: Glucose-induced degradation protein 8, HLJ1_G0042170.mRNA.1.CDS.1, Vacuolar import and degradation protein 24, ...
著者Qiao, S, Cheng, J.D, Schulman, B.A.
登録日2022-02-08
公開日2022-06-08
最終更新日2022-06-15
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Cryo-EM structures of Gid12-bound GID E3 reveal steric blockade as a mechanism inhibiting substrate ubiquitylation.
Nat Commun, 13, 2022
6TTU
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BU of 6ttu by Molmil
Ubiquitin Ligation to substrate by a cullin-RING E3 ligase at 3.7A resolution: NEDD8-CUL1-RBX1 N98R-SKP1-monomeric b-TRCP1dD-IkBa-UB~UBE2D2
分子名称: CYS-LYS-LYS-ALA-ARG-HIS-ASP-SEP-GLY, Cullin-1, E3 ubiquitin-protein ligase RBX1, ...
著者Baek, K, Prabu, J.R, Schulman, B.A.
登録日2019-12-30
公開日2020-02-12
最終更新日2020-03-04
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献NEDD8 nucleates a multivalent cullin-RING-UBE2D ubiquitin ligation assembly.
Nature, 578, 2020
4RG9
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BU of 4rg9 by Molmil
Crystal structure of APC3-APC16 complex (Selenomethionine Derivative)
分子名称: Anaphase-promoting complex subunit 16, Cell division cycle protein 27 homolog
著者Yamaguchi, M, Yu, S, Miller, D.J, Schulman, B.A.
登録日2014-09-29
公開日2014-12-24
最終更新日2017-08-02
実験手法X-RAY DIFFRACTION (3.25 Å)
主引用文献Structure of an APC3-APC16 Complex: Insights into Assembly of the Anaphase-Promoting Complex/Cyclosome.
J.Mol.Biol., 427, 2015
5D7G
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BU of 5d7g by Molmil
Structure of human ATG5 E122D-ATG16L1 complex at 3.0 Angstroms
分子名称: Autophagy protein 5, Autophagy-related protein 16-1
著者Qiu, Y, Schulman, B.A.
登録日2015-08-13
公開日2016-02-03
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Mutation in ATG5 reduces autophagy and leads to ataxia with developmental delay.
Elife, 5, 2016
6WY6
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BU of 6wy6 by Molmil
Crystal structure of S. cerevisiae Atg8 in complex with Ede1 (1220-1247)
分子名称: Autophagy-related protein 8, EH domain-containing and endocytosis protein 1
著者Zheng, Y, Wilfling, F, Baumeister, W, Schulman, B.A.
登録日2020-05-12
公開日2020-12-02
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.773 Å)
主引用文献A Selective Autophagy Pathway for Phase-Separated Endocytic Protein Deposits.
Mol.Cell, 80, 2020
8EBM
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BU of 8ebm by Molmil
Structure of KLHDC2 substrate binding domain bound to KLHDC2's C-degron mimic
分子名称: ASN-GLN-ARG-PHE-GLY-SER-ASN-ASN-THR-SER-GLY-SER, Kelch domain-containing protein 2
著者Scott, D.C, Schulman, B.A.
登録日2022-08-31
公開日2023-02-22
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.58 Å)
主引用文献E3 ligase autoinhibition by C-degron mimicry maintains C-degron substrate fidelity.
Mol.Cell, 83, 2023
8EBN
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BU of 8ebn by Molmil
Structure of KLHDC2-EloB/C tetrameric assembly
分子名称: Elongin-B, Elongin-C, Kelch domain-containing protein 2
著者Scott, D.C, Schulman, B.A.
登録日2022-08-31
公開日2023-02-22
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献E3 ligase autoinhibition by C-degron mimicry maintains C-degron substrate fidelity.
Mol.Cell, 83, 2023
8EBL
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BU of 8ebl by Molmil
Structure of KLHDC2 substrate binding domain bound to C-degron from EPHB2
分子名称: GLU-ASP-SER-HIS-LYS-GLU-SER-ASN-ASP-CYS-SER-CYS-GLY-GLY, Kelch domain-containing protein 2
著者Scott, D.C, Schulman, B.A.
登録日2022-08-31
公開日2023-02-22
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.37 Å)
主引用文献E3 ligase autoinhibition by C-degron mimicry maintains C-degron substrate fidelity.
Mol.Cell, 83, 2023
7OD1
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BU of 7od1 by Molmil
Crystal structure of RBR ubiquitin ligase ARIH2
分子名称: E3 ubiquitin-protein ligase ARIH2, ZINC ION
著者Kostrhon, S.P, Prabu, J.R, Schulman, B.A.
登録日2021-04-28
公開日2021-09-15
最終更新日2021-10-06
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献CUL5-ARIH2 E3-E3 ubiquitin ligase structure reveals cullin-specific NEDD8 activation.
Nat.Chem.Biol., 17, 2021
7ONI
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BU of 7oni by Molmil
Structure of Neddylated CUL5 C-terminal region-RBX2-ARIH2*
分子名称: Cullin-5, E3 ubiquitin-protein ligase ARIH2, NEDD8, ...
著者Kostrhon, S.P, prabu, J.R, Schulman, B.A.
登録日2021-05-25
公開日2021-09-15
最終更新日2021-10-06
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献CUL5-ARIH2 E3-E3 ubiquitin ligase structure reveals cullin-specific NEDD8 activation.
Nat.Chem.Biol., 17, 2021
7Q51
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BU of 7q51 by Molmil
yeast Gid10 bound to a Phe/N-peptide
分子名称: CHLORIDE ION, FWLPANLW peptide, Uncharacterized protein YGR066C
著者Chrustowicz, J, Sherpa, D, Prabu, J.R, Schulman, B.A.
登録日2021-11-02
公開日2022-03-02
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.22 Å)
主引用文献Multifaceted N-Degron Recognition and Ubiquitylation by GID/CTLH E3 Ligases.
J.Mol.Biol., 434, 2022

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件を2024-05-08に公開中

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