8EBN
Structure of KLHDC2-EloB/C tetrameric assembly
Summary for 8EBN
Entry DOI | 10.2210/pdb8ebn/pdb |
Descriptor | Kelch domain-containing protein 2, Elongin-B, Elongin-C, ... (4 entities in total) |
Functional Keywords | e3 ligase, ligase |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 6 |
Total formula weight | 143697.62 |
Authors | Scott, D.C.,Schulman, B.A. (deposition date: 2022-08-31, release date: 2023-02-22, Last modification date: 2023-10-25) |
Primary citation | Scott, D.C.,King, M.T.,Baek, K.,Gee, C.T.,Kalathur, R.,Li, J.,Purser, N.,Nourse, A.,Chai, S.C.,Vaithiyalingam, S.,Chen, T.,Lee, R.E.,Elledge, S.J.,Kleiger, G.,Schulman, B.A. E3 ligase autoinhibition by C-degron mimicry maintains C-degron substrate fidelity. Mol.Cell, 83:770-786.e9, 2023 Cited by PubMed: 36805027DOI: 10.1016/j.molcel.2023.01.019 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.6 Å) |
Structure validation
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