8EBN

Structure of KLHDC2-EloB/C tetrameric assembly

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Kelch domain-containing protein 2	polymer	406	46154.7	2	UniProt (Q9Y2U9) Pfam (PF24681)	Homo sapiens (human)	Hepatocellular carcinoma-associated antigen 33,Host cell factor homolog LCP,Host cell factor-like protein 1,HCLP-1
2	C, E (C, E)	Elongin-B	polymer	104	11748.4	2	UniProt (Q15370) Pfam (PF00240)	Homo sapiens (human)	EloB,Elongin 18 kDa subunit,RNA polymerase II transcription factor SIII subunit B,SIII p18,Transcription elongation factor B polypeptide 2
3	D, F (D, F)	Elongin-C	polymer	121	13945.7	2	UniProt (Q15369) Pfam (PF03931)	Homo sapiens (human)	EloC,Elongin 15 kDa subunit,RNA polymerase II transcription factor SIII subunit C,SIII p15,Transcription elongation factor B polypeptide 1
4	G, H, I, J, K... (A, B, C, D, E...)	water	water		18.0	67	Chemie (HOH)

Sequence modifications

D, F: 16 - 112 (UniProt: Q15369)

PDB	External Database	Details
Met -8	-	expression tag
Ser -7	-	expression tag
Tyr -6	-	expression tag
Tyr -5	-	expression tag
His -4	-	expression tag
His -3	-	expression tag
His -2	-	expression tag
His -1	-	expression tag
His 0	-	expression tag
His 1	-	expression tag
Asp 2	-	expression tag
Tyr 3	-	expression tag
Asp 4	-	expression tag
Ile 5	-	expression tag
Pro 6	-	expression tag
Thr 7	-	expression tag
Thr 8	-	expression tag
Glu 9	-	expression tag
Asn 10	-	expression tag
Leu 11	-	expression tag
Tyr 12	-	expression tag
Phe 13	-	expression tag
Gln 14	-	expression tag
Gly 15	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	143697.6
All*	Total formula weight	143697.6

*Water molecules are not included.