7WUG
GID subcomplex: Gid12 bound Substrate Receptor Scaffolding module
Summary for 7WUG
| Entry DOI | 10.2210/pdb7wug/pdb |
| EMDB information | 32830 |
| Descriptor | Vacuolar import and degradation protein 28, Glucose-induced degradation protein 8, Vacuolar import and degradation protein 30, ... (5 entities in total) |
| Functional Keywords | e3 ubiquitin ligase, beta-propellor, ligase |
| Biological source | Saccharomyces cerevisiae YJM1133 More |
| Total number of polymer chains | 5 |
| Total formula weight | 388591.55 |
| Authors | Qiao, S.,Cheng, J.D.,Schulman, B.A. (deposition date: 2022-02-08, release date: 2022-06-08, Last modification date: 2022-06-15) |
| Primary citation | Qiao, S.,Lee, C.W.,Sherpa, D.,Chrustowicz, J.,Cheng, J.,Duennebacke, M.,Steigenberger, B.,Karayel, O.,Vu, D.T.,von Gronau, S.,Mann, M.,Wilfling, F.,Schulman, B.A. Cryo-EM structures of Gid12-bound GID E3 reveal steric blockade as a mechanism inhibiting substrate ubiquitylation. Nat Commun, 13:3041-3041, 2022 Cited by PubMed: 35650207DOI: 10.1038/s41467-022-30803-9 PDB entries with the same primary citation |
| Experimental method | ELECTRON MICROSCOPY (3.3 Å) |
Structure validation
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