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PDB: 204 results

6ZP0
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Structure of SARS-CoV-2 Spike Protein Trimer (single Arg S1/S2 cleavage site) in Closed State
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein
Authors:Xiong, X, Qu, K, Scheres, S.H.W, Briggs, J.A.G.
Deposit date:2020-07-08
Release date:2020-07-22
Last modified:2021-06-02
Method:ELECTRON MICROSCOPY (3 Å)
Cite:A thermostable, closed SARS-CoV-2 spike protein trimer.
Nat.Struct.Mol.Biol., 27, 2020
6ZP1
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Structure of SARS-CoV-2 Spike Protein Trimer (K986P, V987P, single Arg S1/S2 cleavage site) in Closed State
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein
Authors:Xiong, X, Qu, K, Scheres, S.H.W, Briggs, J.A.G.
Deposit date:2020-07-08
Release date:2020-07-22
Last modified:2021-06-02
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:A thermostable, closed SARS-CoV-2 spike protein trimer.
Nat.Struct.Mol.Biol., 27, 2020
6ZOZ
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BU of 6zoz by Molmil
Structure of Disulphide-stabilized SARS-CoV-2 Spike Protein Trimer (x1 disulphide-bond mutant, S383C, D985C, K986P, V987P, single Arg S1/S2 cleavage site) in Locked State
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, BILIVERDINE IX ALPHA, ...
Authors:Xiong, X, Qu, K, Scheres, S.H.W, Briggs, J.A.G.
Deposit date:2020-07-08
Release date:2020-07-22
Last modified:2024-10-16
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:A thermostable, closed SARS-CoV-2 spike protein trimer.
Nat.Struct.Mol.Biol., 27, 2020
7A5V
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CryoEM structure of a human gamma-aminobutyric acid receptor, the GABA(A)R-beta3 homopentamer, in complex with histamine and megabody Mb25 in lipid nanodisc
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, ...
Authors:Nakane, T, Kotecha, A, Sente, A, Yamashita, K, McMullan, G, Masiulis, S, Brown, P.M.G.E, Grigoras, I.T, Malinauskaite, L, Malinauskas, T, Miehling, J, Yu, L, Karia, D, Pechnikova, E.V, de Jong, E, Keizer, J, Bischoff, M, McCormack, J, Tiemeijer, P, Hardwick, S.W, Chirgadze, D.Y, Murshudov, G, Aricescu, A.R, Scheres, S.H.W.
Deposit date:2020-08-22
Release date:2020-11-18
Last modified:2020-11-25
Method:ELECTRON MICROSCOPY (1.7 Å)
Cite:Single-particle cryo-EM at atomic resolution.
Nature, 587, 2020
7ARE
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BU of 7are by Molmil
DNA origami pointer object v2
Descriptor: SCAFFOLD STRAND, STAPLE STRAND
Authors:Thomas, M, Feigl, E, Kohler, F, Kube, M, Nagel-Yuksel, B, Willner, E.M, Funke, J.J, Gerling, T, Stommer, P, Honemann, M.N, Martin, T.G, Scheres, S.H.W, Dietz, H.
Deposit date:2020-10-24
Release date:2020-11-18
Last modified:2024-05-01
Method:ELECTRON MICROSCOPY (7.4 Å)
Cite:Revealing the structures of megadalton-scale DNA complexes with nucleotide resolution.
Nat Commun, 11, 2020
7AS5
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126 helix bundle DNA nanostructure
Descriptor: SCAFFOLD STRAND, STAPLE STRAND
Authors:Kube, M, Kohler, F, Feigl, E, Nagel-Yuksel, B, Willner, E.M, Funke, J.J, Gerling, T, Stommer, P, Honemann, M.N, Martin, T.G, Scheres, S.H.W, Dietz, H.
Deposit date:2020-10-27
Release date:2020-11-18
Last modified:2024-05-15
Method:ELECTRON MICROSCOPY (9.8 Å)
Cite:Revealing the structures of megadalton-scale DNA complexes with nucleotide resolution.
Nat Commun, 11, 2020
7ART
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BU of 7art by Molmil
48 helix bundle DNA origami brick
Descriptor: SCAFFOLD STRAND, STAPLE STRAND
Authors:Feigl, E, Kube, M, Kohler, F, Nagel-Yuksel, B, Willner, E.M, Funke, J.J, Gerling, T, Stommer, P, Honemann, M.N, Martin, T.G, Scheres, S.H.W, Dietz, H.
Deposit date:2020-10-26
Release date:2020-11-11
Last modified:2024-05-15
Method:ELECTRON MICROSCOPY (10 Å)
Cite:Revealing the structures of megadalton-scale DNA complexes with nucleotide resolution.
Nat Commun, 11, 2020
5O3T
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Straight filament in Alzheimer's disease brain
Descriptor: Microtubule-associated protein tau
Authors:Fitzpatrick, A.W.P, Falcon, B, He, S, Murzin, A.G, Murshudov, G, Garringer, H.G, Crowther, R.A, Ghetti, B, Goedert, M, Scheres, S.H.W.
Deposit date:2017-05-24
Release date:2017-07-26
Last modified:2024-05-15
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Cryo-EM structures of tau filaments from Alzheimer's disease.
Nature, 547, 2017
5O3O
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Pronase-treated paired helical filament in Alzheimer's disease brain
Descriptor: Microtubule-associated protein tau
Authors:Fitzpatrick, A.W.P, Falcon, B, He, S, Murzin, A.G, Murshudov, G, Garringer, H.G, Crowther, R.A, Ghetti, B, Goedert, M, Scheres, S.H.W.
Deposit date:2017-05-24
Release date:2017-07-26
Last modified:2024-05-15
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Cryo-EM structures of tau filaments from Alzheimer's disease.
Nature, 547, 2017
5O3L
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Paired helical filament in Alzheimer's disease brain
Descriptor: Microtubule-associated protein tau
Authors:Fitzpatrick, A.W.P, Falcon, B, He, S, Murzin, A.G, Murshudov, G, Garringer, H.G, Crowther, R.A, Ghetti, B, Goedert, M, Scheres, S.H.W.
Deposit date:2017-05-24
Release date:2017-07-26
Last modified:2024-05-15
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Cryo-EM structures of tau filaments from Alzheimer's disease.
Nature, 547, 2017
8ORF
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BU of 8orf by Molmil
Cryo-EM structure of SH-SY5Y seeded with filaments from corticobasal degeneration extracts
Descriptor: Microtubule-associated protein tau
Authors:Lovestam, S, Scheres, S.H.W, Goedert, M.
Deposit date:2023-04-13
Release date:2023-04-26
Last modified:2024-07-24
Method:ELECTRON MICROSCOPY (2.5 Å)
Cite:Cryo-EM structures of tau filaments from SH-SY5Y cells seeded with brain extracts from cases of Alzheimer's disease and corticobasal degeneration.
Febs Open Bio, 13, 2023
8ORG
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BU of 8org by Molmil
Cryo-EM structure of SH-SY5Y seeded with filaments from corticobasal degeneration extracts (Type II)
Descriptor: Microtubule-associated protein tau
Authors:Lovestam, S, Scheres, S.H.W, Goedert, M.
Deposit date:2023-04-13
Release date:2023-04-26
Last modified:2024-07-24
Method:ELECTRON MICROSCOPY (2.3 Å)
Cite:Cryo-EM structures of tau filaments from SH-SY5Y cells seeded with brain extracts from cases of Alzheimer's disease and corticobasal degeneration.
Febs Open Bio, 13, 2023
8ORE
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BU of 8ore by Molmil
Cryo-EM structure of SH-SY5Y seeded with filaments from Alzheimer's Disease
Descriptor: Microtubule-associated protein tau
Authors:Lovestam, S, Scheres, S.H.W, Goedert, M.
Deposit date:2023-04-13
Release date:2023-04-26
Last modified:2024-07-24
Method:ELECTRON MICROSCOPY (2.5 Å)
Cite:Cryo-EM structures of tau filaments from SH-SY5Y cells seeded with brain extracts from cases of Alzheimer's disease and corticobasal degeneration.
Febs Open Bio, 13, 2023
8P34
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Tau filaments extracted from human brain with the DeltaK281 mutation in MAPT
Descriptor: Microtubule-associated protein tau
Authors:Schweighauser, M, Garringer, H.J, Klingstedt, T, Masuda-Suzukake, M, Murrell, J.R, Vidal, R, Scheres, S.H.W, Goedert, M, Ghetti, B, Newell, K.L.
Deposit date:2023-05-17
Release date:2023-07-05
Last modified:2024-07-24
Method:ELECTRON MICROSCOPY (2.61 Å)
Cite:Mutation ∆K281 in MAPT causes Pick's disease.
Acta Neuropathol, 146, 2023
7QJW
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BU of 7qjw by Molmil
In vitro assembled tau filaments with structures like chronic traumatic encephalopathy type II (8a)
Descriptor: Microtubule-associated protein tau
Authors:Lovestam, S, Scheres, S.H.W.
Deposit date:2021-12-17
Release date:2022-01-19
Last modified:2024-07-17
Method:ELECTRON MICROSCOPY (2.81 Å)
Cite:Assembly of recombinant tau into filaments identical to those of Alzheimer's disease and chronic traumatic encephalopathy.
Elife, 11, 2022
7QKF
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BU of 7qkf by Molmil
In vitro assembled 266/297 - 391 tau filaments with CuCl2 (12a)
Descriptor: Microtubule-associated protein tau
Authors:Lovestam, S, Scheres, S.H.W.
Deposit date:2021-12-17
Release date:2022-02-16
Last modified:2024-10-09
Method:ELECTRON MICROSCOPY (2.83 Å)
Cite:Assembly of recombinant tau into filaments identical to those of Alzheimer's disease and chronic traumatic encephalopathy.
Elife, 11, 2022
7QL3
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BU of 7ql3 by Molmil
in vitro assembled 266/297 - 391 tau filaments with NaCl (8b)
Descriptor: Microtubule-associated protein tau
Authors:Lovestam, S, Scheres, S.H.W.
Deposit date:2021-12-19
Release date:2022-02-16
Last modified:2024-07-17
Method:ELECTRON MICROSCOPY (3.32 Å)
Cite:Assembly of recombinant tau into filaments identical to those of Alzheimer's disease and chronic traumatic encephalopathy.
Elife, 11, 2022
7QJV
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BU of 7qjv by Molmil
In vitro assembled tau filaments into Quadruple Helical Filaments type 1 (2c)
Descriptor: Microtubule-associated protein tau
Authors:Lovestam, S, Scheres, S.H.W.
Deposit date:2021-12-17
Release date:2022-02-16
Last modified:2024-07-17
Method:ELECTRON MICROSCOPY (3.29 Å)
Cite:Assembly of recombinant tau into filaments identical to those of Alzheimer's disease and chronic traumatic encephalopathy.
Elife, 11, 2022
7QKL
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BU of 7qkl by Molmil
In vitro assembled 266/297 - 391 tau filaments with ZnCl2 (11a)
Descriptor: Microtubule-associated protein tau
Authors:Lovestam, S, Scheres, S.H.W.
Deposit date:2021-12-17
Release date:2022-02-16
Last modified:2024-07-17
Method:ELECTRON MICROSCOPY (2.07 Å)
Cite:Assembly of recombinant tau into filaments identical to those of Alzheimer's disease and chronic traumatic encephalopathy.
Elife, 11, 2022
7QK1
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BU of 7qk1 by Molmil
In vitro assembled 297-394 tau filaments in PBS (35d)
Descriptor: Microtubule-associated protein tau
Authors:Lovestam, S, Scheres, S.H.W.
Deposit date:2021-12-17
Release date:2022-02-16
Last modified:2024-07-17
Method:ELECTRON MICROSCOPY (3.03 Å)
Cite:Assembly of recombinant tau into filaments identical to those of Alzheimer's disease and chronic traumatic encephalopathy.
Elife, 11, 2022
7QL0
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BU of 7ql0 by Molmil
In vitro assembled 266/297 - 391 tau filaments with MgSO4 and NaCl (15c)
Descriptor: Microtubule-associated protein tau
Authors:Lovestam, S, Scheres, S.H.W.
Deposit date:2021-12-19
Release date:2022-02-16
Last modified:2024-07-17
Method:ELECTRON MICROSCOPY (3.13 Å)
Cite:Assembly of recombinant tau into filaments identical to those of Alzheimer's disease and chronic traumatic encephalopathy.
Elife, 11, 2022
7QKM
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BU of 7qkm by Molmil
In vitro assembled 266-391 S356D tau filaments with NaCl (45a)
Descriptor: Microtubule-associated protein tau
Authors:Lovestam, S, Scheres, S.H.W.
Deposit date:2021-12-17
Release date:2022-02-16
Last modified:2024-07-17
Method:ELECTRON MICROSCOPY (2.66 Å)
Cite:Assembly of recombinant tau into filaments identical to those of Alzheimer's disease and chronic traumatic encephalopathy.
Elife, 11, 2022
7QKK
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BU of 7qkk by Molmil
In vitro assembled 258-391 tau filaments with phosphoglycerate, 700 rpm (39a)
Descriptor: Microtubule-associated protein tau
Authors:Lovestam, S, Scheres, S.H.W.
Deposit date:2021-12-17
Release date:2022-02-16
Last modified:2024-07-17
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:Assembly of recombinant tau into filaments identical to those of Alzheimer's disease and chronic traumatic encephalopathy.
Elife, 11, 2022
7QL1
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BU of 7ql1 by Molmil
In vitro assembled 266-391 tau filaments in PBS (23a)
Descriptor: Microtubule-associated protein tau
Authors:Lovestam, S, Scheres, S.H.W.
Deposit date:2021-12-19
Release date:2022-02-16
Last modified:2024-07-17
Method:ELECTRON MICROSCOPY (3.34 Å)
Cite:Assembly of recombinant tau into filaments identical to those of Alzheimer's disease and chronic traumatic encephalopathy.
Elife, 11, 2022
7QKI
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In vitro assembled 297-408 S396D S400D T403D S404D tau filaments (42a)
Descriptor: Microtubule-associated protein tau
Authors:Lovestam, S, Scheres, S.H.W.
Deposit date:2021-12-17
Release date:2022-02-16
Last modified:2024-07-17
Method:ELECTRON MICROSCOPY (3.13 Å)
Cite:Assembly of recombinant tau into filaments identical to those of Alzheimer's disease and chronic traumatic encephalopathy.
Elife, 11, 2022

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